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A 23-year-old woman with long-standing insulin dependent diabetes presented with necrobiosis lipoidica. She was particularly troubled by the telangiectatic element of the lesion and therefore underwent test treatment with the pulsed dye laser. At low fluences minimal therapeutic effect was achieved, and at higher fluences skin breakdown occurred. This resolved with conservative management. It would appear that caution is required when attempting to treat necrobiosis lipoidica with laser. 相似文献
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A temporal high-pass filtration technique for digital subtraction angiocardiography was studied, using real-time digital studies performed simultaneously with routine cineangiocardiography (cine) for qualitative image comparison. The digital studies showed increased contrast and suppression of background anatomy and also enhanced detection of wall motion abnormalities when compared with cine. This digital technique is compatible with panning the image intensifier during an injection. The digital images are comparable with, and in some cases better than, cine images. Clinical efficacy of this digital technique is currently being evaluated. Real-time display, as well as potential reductions in radiation and contrast material doses, may make digital angiocardiography an attractive technique. 相似文献
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Wai Lone Lim BEng PhD Yong Tian Chew PhD MEng BE Krishnan B Chandran PhD Hong Tong Low PhD MEng BEng Kok Yong Seng BEng 《Journal of artificial organs》2000,3(2):162-165
Cavitation bubble formation associated with mechanical valve closure has been investigated in vitro, and the region of bubble
formation has been correlated with large negative pressure transients. The region of cavitation bubbles forms in valve designs
where leaflets interact with seat stops. It has been postulated that the fluid is squeezed between the leaflet and the seat
stop and radially propelled at high velocities, resulting in further pressure reduction below the vapor pressure of fluid
and initiating cavitation bubble formation. We conducted in vitro experiments to visualize and detect the presence of squeeze-flow
phenomena associated with valve closure of mechanical heart valves. The closing dynamics were studied by simulating a single
closing event of the leaflet with the valve mounted at the mitral position. Squeeze flow was detected at the instant of valve
closure, when the valve leaflet interacts with the valve seat stop. The use of a high-speed video camera at 1000 frames per
second with strobe light at 16000 pulses per second enabled the visualization of cavitation bubbles and its radial motion
from the valve's seat stop due to the squeeze-flow effect. Vapor cavitation bubbles were observed to collapse within 0.5 ms
after inception. In mechanical valves without seat stops in the major orifice region, bubbles of duration longer than that
of the cavitation bubbles were observed. These microbubbles were present for 4 s before collapsing and are believed to be
air bubbles whose presence in vivo has been detected with ultrasound imaging. 相似文献