Follow-up of a web-based tailored intervention promoting the Mediterranean diet in Scotland

Objective

To assess the impact of a 3-month follow-up of a 6-month quasi-experimental study conducted to evaluate a web-based, tailored-feedback intervention promoting four key components of the Mediterranean diet.

Methods

Fifty-three (intervention) and nineteen (control) healthy females, 25–55 years, employed at two Universities in Glasgow, Scotland, between 2003 and 2004 participated. Participants received tailored dietary and psychosocial feedback and Internet education, or minimal dietary feedback and general healthy-eating brochures, respectively. Dietary intake using 7d-estimated food diaries and blood lipids were assessed at baseline, 6 (post-test) and 9 months (follow-up).

Results

Intention-to-treat analyses for between-group comparisons over time showed that the intervention group had increased their vegetable intake over 9 months and had more favourable levels of HDL-cholesterol and ratio of total:HDL-cholesterol over the 9-month assessment, compared with the control group. Within-group comparisons showed that, except for fruit consumption, the intervention group sustained their dietary improvement at 9 months, compared with baseline.

Conclusion

This intervention proved successful at sustaining most of the favourable dietary and blood lipid profile changes achieved over the 6-month intervention at the 3-month follow-up.

Practice implications

This intervention can be effective in promoting a Mediterranean-style diet in work settings.     

External quality assessment of SARS-CoV-2 serology in European expert laboratories,April 2021

BackgroundCountries worldwide are focusing to mitigate the ongoing SARS-CoV-2 pandemic by employing public health measures. Laboratories have a key role in the control of SARS-CoV-2 transmission. Serology for SARS-CoV-2 is of critical importance to support diagnosis, define the epidemiological framework and evaluate immune responses to natural infection and vaccine administration.AimThe aim of this study was the assessment of the actual capability among laboratories involved in sero-epidemiological studies on COVID-19 in EU/EEA and EU enlargement countries to detect SARS-CoV-2 antibodies through an external quality assessment (EQA) based on proficiency testing.MethodsThe EQA panels were composed of eight different, pooled human serum samples (all collected in 2020 before the vaccine roll-out), addressing sensitivity and specificity of detection. The panels and two EU human SARS-CoV-2 serological standards were sent to 56 laboratories in 30 countries.ResultsThe overall performance of laboratories within this EQA indicated a robust ability to establish past SARS-CoV-2 infections via detection of anti-SARS-CoV-2 antibodies, with 53 of 55 laboratories using at least one test that characterised all EQA samples correctly. IgM-specific test methods provided most incorrect sample characterisations (24/208), while test methods detecting total immunoglobulin (0/119) and neutralising antibodies (2/230) performed the best. The semiquantitative assays used by the EQA participants also showed a robust performance in relation to the standards.ConclusionOur EQA showed a high capability across European reference laboratories for reliable diagnostics for SARS-CoV-2 antibody responses. Serological tests that provide robust and reliable detection of anti-SARS-CoV-2 antibodies are available.     

Cardiac tamponade complicating ventricular arrhythmia ablation: Real life data on incidence,management, and outcome

Background and Objective

Cardiac tamponade during ablation procedures is a life-threatening complication. While the incidence and management of tamponade in atrial fibrillation ablation have been extensively described, the data on tamponade during ventricular ablations are very limited. The purpose of this study is to shed light on the incidence, typical perforation sites, and optimal management as observed through real-life data in a tertiary referral center for ventricular ablation.

Methods and Results

Consecutive patients with structural heart disease undergoing ventricular tachycardia ablation from 2008–2020 were analyzed. Of the 1078 patients undergoing 1287 ventricular ablation procedures, 20 procedures (1.5%) were complicated by cardiac tamponade. In all but one patient, the tamponade was treated with emergent pericardial drainage, while nine patients eventually underwent surgical repair. The perforation occurred during transseptal or subxiphoid puncture in six patients, during ventricle mapping in two patients, and during ablation in five patients (predominantly basal left ventricle). Steam pop as definite perforation cause could only be established in two patients. Regardless of the management of the complication, all patients survived to discharge.

Conclusion

Cardiac tamponade during ventricular ablation occurred in 1.5% of the procedures. In nine patients cardiac repair was necessary. Perforation was mostly associated with subxiphoid puncture or ablation of the basal left ventricle.