全文获取类型
收费全文 | 46849篇 |
免费 | 2940篇 |
国内免费 | 272篇 |
专业分类
耳鼻咽喉 | 468篇 |
儿科学 | 1316篇 |
妇产科学 | 1212篇 |
基础医学 | 6161篇 |
口腔科学 | 997篇 |
临床医学 | 4611篇 |
内科学 | 10435篇 |
皮肤病学 | 898篇 |
神经病学 | 5105篇 |
特种医学 | 1531篇 |
外科学 | 6161篇 |
综合类 | 181篇 |
一般理论 | 19篇 |
预防医学 | 3462篇 |
眼科学 | 773篇 |
药学 | 2906篇 |
1篇 | |
中国医学 | 90篇 |
肿瘤学 | 3734篇 |
出版年
2024年 | 70篇 |
2023年 | 530篇 |
2022年 | 1023篇 |
2021年 | 1835篇 |
2020年 | 1070篇 |
2019年 | 1515篇 |
2018年 | 1744篇 |
2017年 | 1225篇 |
2016年 | 1362篇 |
2015年 | 1568篇 |
2014年 | 2156篇 |
2013年 | 2721篇 |
2012年 | 4041篇 |
2011年 | 4012篇 |
2010年 | 2040篇 |
2009年 | 1905篇 |
2008年 | 3221篇 |
2007年 | 3100篇 |
2006年 | 2809篇 |
2005年 | 2778篇 |
2004年 | 2320篇 |
2003年 | 2088篇 |
2002年 | 1847篇 |
2001年 | 310篇 |
2000年 | 238篇 |
1999年 | 309篇 |
1998年 | 316篇 |
1997年 | 236篇 |
1996年 | 214篇 |
1995年 | 196篇 |
1994年 | 165篇 |
1993年 | 131篇 |
1992年 | 116篇 |
1991年 | 108篇 |
1990年 | 85篇 |
1989年 | 66篇 |
1988年 | 71篇 |
1987年 | 61篇 |
1986年 | 52篇 |
1985年 | 53篇 |
1984年 | 52篇 |
1983年 | 38篇 |
1982年 | 43篇 |
1981年 | 26篇 |
1980年 | 26篇 |
1979年 | 22篇 |
1978年 | 20篇 |
1977年 | 18篇 |
1975年 | 14篇 |
1974年 | 15篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
Medicine, Health Care and Philosophy - Can transfusions of blood plasma slow down ageing or even rejuvenate people? Recent preclinical studies and experimental tests inspired by the technique known... 相似文献
32.
Elisa Giani Andrea Enzo Scaramuzza Gian Vincenzo Zuccotti 《World journal of diabetes》2015,6(8):999-1004
Technologies for diabetes management, such as continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM) systems, have improved remarkably over the last decades. These developments are impacting the capacity to achieve recommended hemoglobin A1c levels and assisting in preventing the development and progression of micro- and macro vascular complications. While improvements in metabolic control and decreases in risk of severe and moderate hypoglycemia have been described with use of these technologies, large epidemiological international studies show that many patients are still unable to meet their glycemic goals, even when these technologies are used. This editorial will review the impact of technology on glycemic control, hypoglycemia and quality of life in children and youth with type 1 diabetes. Technologies reviewed include CSII, CGM systems and sensor-augmented insulin pumps. In addition, the usefulness of advanced functions such as bolus profiles, bolus calculators and threshold-suspend features will be also discussed. Moreover, the current editorial will explore the challenges of using these technologies. Indeed, despite the evidence currently available of the potential benefits of using advanced technologies in diabetes management, many patients still report barriers to using them. Finally this article will highlight the importance of future studies tailored toward overcome these barriers to optimizing glycemic control and avoiding severe hypoglycemia. 相似文献
33.
Jerome Marley Julia Taylor Jane Brocksom Kath Schubach Andrea Nixon Paula Allchorne Susanne Vahr Lauridsen 《International Journal of Urological Nursing》2020,14(1):5-12
A series of three World Café events centred on the topic of developing an Educational Framework for Urological Nursing [EFUN] were held by the British Association of Urological Nurses [BAUN], the European Association of Urology Nurses [EAUN] and the Australian and New Zealand Urological Nursing Society [ANZUNS] between 2017 and 2019. About 376 urology nurses participated in these “conversations that matter” and generated 1047 individual response items that were grouped into themes to assist the three associations to take the creation of an EFUN to the next level. Areas explored centred on four aspects: what any agreed educational framework for urology nursing should contain; the academic level at which education should be provided; who should be recruited as collaborators on writing an educational framework and, lastly, just how any emergent framework should be used. Analysis of the conversational data indicate that there exists within the urological nursing community a collective wisdom regarding their educational needs and how these needs should be met. 相似文献
34.
35.
36.
37.
38.
Marco Maruzzo Umberto Basso Eugenio Borsatti Laura Evangelista Filippo Alongi Orazio Caffo Francesca Maines Sara Galuppo Rocco De Vivo Fable Zustovich Dario Palleschi Andrea Zivi Teodoro Sava Mariella Sorarù Roberto Iacovelli Maurizio Nicodemo Susanne Baier Lucia Fratino Vittorina Zagonel 《Clinical genitourinary cancer》2019,17(1):e187-e194
Background
Radium 223 was introduced for metastatic castration-resistant prostate cancer based on the results of a randomized controlled trial showing risk reduction for death and skeletal events. Our aim was to evaluate the outcome of patients receiving radium 223 in a real-world setting.Patients and Methods
We conducted a multicenter retrospective analysis in the Triveneto region of Italy.Results
One hundred fifty-eight patients received radium 223 in our region. After a median follow-up of 9.5 months, 75 patients died. The median overall survival (OS) was 14.2 months, and the median progression-free survival (PFS) was 6.2 months. Seventy-one (45%) patients achieved progression as best response. Thirty-seven (23%) patients stopped the treatment early because of progression. Eastern Cooperative Oncology Group performance status was prognostic for OS (18.4 vs. 12.3 vs. 7.5 months; 0 vs. 1, P = .0062; 0 vs. 2, P = .0002), whereas previous prostatectomy or docetaxel exposure were not. A neutrophil to lymphocytes ratio ≥ 3 significantly impacted OS (18.1 vs. 9.7 months; P < .001) and slightly impacted PFS (6.6 vs. 5.6 months; P = .05). Patients with a baseline alkaline phosphatase (ALP) value ≥ 220 U/L had worse OS and PFS (24.1 vs. 10.5 months; 7.2 vs. 5.5 months; P < .001). Patients with changes in ALP value achieved better OS (P = .029) and PFS (P = .002). There was no difference according to the line of therapy (0 vs. ≥ 1; P = .490). The main grade 3/4 toxicities were anemia, asthenia, and thrombocytopenia.Conclusion
This large real-world report confirms comparable OS and PFS data when compared with the pivotal study, as well as the predictive role of ALP and neutrophil to lymphocytes ratio. The definition of the optimal position of radium 223 in the treatment of metastatic castration-resistant prostate cancer has still to be defined. 相似文献39.
Darren R. Feldman MD Yasser Ged MBBS Chung-Han Lee PhD Andrea Knezevic MS Ana M. Molina MD Ying-Bei Chen PhD Joshua Chaim DO Devyn T. Coskey MS Samuel Murray MS Satish K. Tickoo MD Victor E. Reuter MD Sujata Patil PhD Han Xiao MD Jahan Aghalar MD Arlyn J. Apollo MD Maria I. Carlo MD Robert J. Motzer MD Martin H. Voss MD 《Cancer》2020,126(24):5247-5255
40.