全文获取类型
收费全文 | 269038篇 |
免费 | 16714篇 |
国内免费 | 641篇 |
专业分类
耳鼻咽喉 | 3193篇 |
儿科学 | 8164篇 |
妇产科学 | 5653篇 |
基础医学 | 38447篇 |
口腔科学 | 10335篇 |
临床医学 | 20810篇 |
内科学 | 57487篇 |
皮肤病学 | 5765篇 |
神经病学 | 23963篇 |
特种医学 | 9499篇 |
外国民族医学 | 35篇 |
外科学 | 33572篇 |
综合类 | 1866篇 |
现状与发展 | 1篇 |
一般理论 | 154篇 |
预防医学 | 29494篇 |
眼科学 | 4785篇 |
药学 | 16133篇 |
中国医学 | 886篇 |
肿瘤学 | 16151篇 |
出版年
2023年 | 1278篇 |
2022年 | 2603篇 |
2021年 | 5088篇 |
2020年 | 3470篇 |
2019年 | 4955篇 |
2018年 | 6712篇 |
2017年 | 5229篇 |
2016年 | 5157篇 |
2015年 | 5913篇 |
2014年 | 8139篇 |
2013年 | 10449篇 |
2012年 | 16158篇 |
2011年 | 16803篇 |
2010年 | 8567篇 |
2009年 | 8166篇 |
2008年 | 13696篇 |
2007年 | 14473篇 |
2006年 | 13566篇 |
2005年 | 13631篇 |
2004年 | 12409篇 |
2003年 | 11486篇 |
2002年 | 9175篇 |
2001年 | 8478篇 |
2000年 | 8442篇 |
1999年 | 7485篇 |
1998年 | 2849篇 |
1997年 | 2362篇 |
1996年 | 2416篇 |
1995年 | 2022篇 |
1994年 | 1955篇 |
1993年 | 1777篇 |
1992年 | 4866篇 |
1991年 | 4478篇 |
1990年 | 4211篇 |
1989年 | 4055篇 |
1988年 | 3685篇 |
1987年 | 3376篇 |
1986年 | 3155篇 |
1985年 | 3017篇 |
1984年 | 2168篇 |
1983年 | 1805篇 |
1982年 | 1012篇 |
1981年 | 895篇 |
1980年 | 834篇 |
1979年 | 1653篇 |
1978年 | 1060篇 |
1977年 | 845篇 |
1975年 | 856篇 |
1974年 | 903篇 |
1973年 | 891篇 |
排序方式: 共有10000条查询结果,搜索用时 12 毫秒
91.
Occupational airborne allergic contact dermatitis from tylosin 总被引:2,自引:1,他引:1
92.
Plasma D-dimer (DD) and thrombin--antithrombin III complex (TAT) were measured with ELISAs in 99 patients investigated by 102 ventilation--perfusion lung scintigraphy because of suspected pulmonary embolism. High-probability lung scan was associated with increased DD (more than 500 ng/ml) and TAT (more than 4.1 ng/ml) levels (sensitivity of 100 and 70%, respectively). The corresponding figures of specificity were 81 and 42%. In the 56 patients with low-probability or indeterminate probability scans, 31 (55%) had DD concentrations of less than 500 ng/ml. These preliminary data suggest that a plasma DD concentration of less than 500 ng/ml might rule out the diagnosis of pulmonary embolism in suspected patients with an inconclusive lung scanning. 相似文献
93.
J. de Rotrou L. Battal-Merlet E. Wenisch C. Chausson E. Bizet F. Dray H. Lenoir A.-S. Rigaud O. Hanon 《European journal of neurology》2007,14(2):144-149
Within the context of early diagnosis of Alzheimer's disease (AD), there is a growing interest in neuropsychological screening tests. Amongst these tests, we focused on the largely used Memory Impairment Screen (MIS). The objective of the present work was to show that adding a 10-min delayed recall to the MIS, improves the test psychometric characteristics in order to detect dementia in the earliest stages. A prospective study was carried out on a cohort of 270 consecutive elderly ambulatory subjects attending the Broca Hospital Memory Clinic: normal controls ( n = 67), mild cognitive impairment subjects ( n = 98) and mildly demented patients [ n = 105, Mini Mental State Examination (MMSE) = 23 ± 4]. This study consisted in testing the advantage of the 10-min delayed recall entitled MIS-D compared with the MIS. At a cut-off score of 6, the MIS-D revealed satisfying psychometric characteristics with a sensitivity of 81% and a specificity of 91%, whilst the MIS alone indicated a sensitivity of 60% and a specificity of 88% in detecting dementia. In demented patients with MMSE score ≥26, MIS-D properties still remained satisfying (sensitivity: 75%, specificity: 92%). MIS-D is a more relevant screening test than MIS alone at very early stages of dementia. 相似文献
94.
Pieter M. Groenendijk August A. B. Lycklama Nijeholt Theo J. Ouwerkerk Ubi van den Hombergh 《Neuromodulation》2007,10(4):363-368
Objective. We studied long‐term clinical efficacy of sacral neuromodulation (SNM) therapy in patients with refractory urgency incontinence (UI), urgency/frequency (UF) and voiding difficulty (VD), together with urodynamic data at baseline and six months postimplant. Materials and Methods. Twenty‐two patients were implanted with a neurostimulator after a positive response to a percutaneous nerve evaluation test defined as a greater than 50% improvement in symptoms. Results. At five‐year follow‐up, the number of incontinent episodes and pad usage per day decreased significantly in 10 out of 15 UI patients. Two of five UF patients were successfully treated with SNM; the number of daily voids for all UF patients decreased from 25 to 19 and average voided volume increased from 98 to 212 mL. One of the two VD patients was able to void to completion. Mean first sensation of filling at the six‐month urodynamic investigation for the UI and UF patients increased from 78 to 241 mL and 141 to 232 mL, respectively, and the maximum bladder capacity increased from 292 to 352 mL and 223 to 318 mL, respectively. Five of 22 patients underwent device explant and one patient still has an inactive stimulator implanted. Conclusion. SNM is an effective treatment modality that offers sustained clinical benefit in the majority of patients with refractory UI, UF, and VD that do not respond to other, more conservative therapies. 相似文献
95.
Marcos Ribeiro Luciene Angelini Priscila Games Robles-Ribeiro Rafael Stelmach Ubiratan de Paula Santos Mario Terra-Filho 《The Journal of asthma》2007,44(5):371-375
Background. The European Community Respiratory Health Survey (ECRHS) questionnaire was planned to answer questions about the distribution of asthma. Our objective was to determine the cultural equivalence of the ECRHS into the Brazilian-Portuguese language. Methods. We translated the ECRHS according to international criteria. Results. Small cultural adaptations were necessary. Among the 80 participating patients, the Cronbach indices were higher (0.98-1.00) and the Kappa indices varied from 0.77 to 1.00. Conclusion. The study suggests that the Brazilian version of the ECRHS is conceptually equivalent to the original and similarly reliable and may be used in international studies involving Portuguese-speaking respiratory patients. 相似文献
96.
Chronic intestinal pseudo-obstruction: manifestations, natural history and management 总被引:2,自引:0,他引:2
v. stanghellini r. f. cogliandro r. de giorgio g. barbara b. salvioli & r. corinaldesi 《Neurogastroenterology and motility》2007,19(6):440-452
Chronic intestinal pseudo-obstruction (CIPO) is a rare pathological condition characterized by a marked derangement of gut propulsive motility mimicking mechanical obstruction, in the absence of any lesion occluding the gut lumen. This disease is often associated with a disabling and potentially life-threatening complications and is still too often unrecognized even in referral centres. As a result, patients receive neither appropriate care nor recognition of their severe health condition. Medical and surgical therapies are often unsatisfactory and long-term outcome turns out to be poor in the vast majority of cases. This article focuses on the main clinical features, the management and long-term outcome of patients affected by CIPO, with particular emphasis on those aspects which remain a matter of debate. 相似文献
97.
Mycobacterium ulcerans infection in Ashanti region, Ghana 总被引:1,自引:0,他引:1
T S van der Werf W T van der Graaf D G Groothuis A J Knell 《Transactions of the Royal Society of Tropical Medicine and Hygiene》1989,83(3):410-413
We describe a series of 96 cases of Mycobacterium ulcerans infection (Buruli ulcer) from a new endemic focus in the Afram valley, north of Agogo, in Ghana. 63 cases were children under 13 years old. Active treatment by excision and skin grafting necessitates long stays in hospital and repeated procedures. Scarring and contracture are frequent. Eyes and other vital organs may be destroyed. In its endemic foci Buruli ulcer is a serious health burden on rural populations. Research is urgently needed, especially in prevention and non-surgical management. 相似文献
98.
99.
J J de Souza T Perlmann A A Herman O J Ransome R W Kantor 《Suid-Afrikaanse tydskrif vir geneeskunde》1987,71(11):690-692
The value of maternal C-reactive protein (CRP) levels as predictors of fetal and maternal infective morbidity and fetal mortality was assessed prospectively over a 6-month period in all cases of premature rupture of the fetal membranes or suspected premature labour. Statistical analysis of results showed that CRP at a level of 1.32 mg/dl is a sensitive marker of infective morbidity in mother and neonate. Furthermore, there was a significant association between raised CRP levels and low-birth-weight babies, suggesting that intra-uterine infection is a major cause of prematurity in the study population. 相似文献
100.