结节性甲状腺肿及其非典型结节与甲状腺癌细胞核DNA定量研究

作者对结节性甲状腺肿及其非典型结节与甲状腺癌细胞核直径、面积及 DNA 含量检测,发现核直径与面积的(?)和 S 为甲状腺癌组>非典型结节组>对照组(P<0.01);随着细胞增生异型程度的加重,核直径、面积及离散程度随之增加、DNA 含量也显著增加,显示Ⅲ级 DNA 含量细胞出现频率越高恶性的可能性就越大;同时发现各组细胞核不同 DNA 含量的核直径、面积均明显增加,与对照组相比差异生非常显著(P<0.01)。     

颞下颌关节的三维有限元法研究

本研究利用颞下颌关节ＣＴ扫描资料和计算机图像分析处理技术以及三维有限元方法相结合建立了髁状突的三维有限元模型，结果表明，此方法在技术上是可行的并将有助于颞下颌关节的临床和基础研究。     

不锈钢清创车在外伤伤口清创中的应用

清洗伤口时病人血液常常易溅到医护人员的衣服及地面上，造成环境污染，甚至威胁医护人员的健康。我科于2002年3月设计了不锈钢清创车，经过2年临床使用，效果满意。     

Family physicians' perceptions of academic detailing: a quantitative and qualitative study

Background  

The efficacy of academic detailing in changing physicians' knowledge and practice has been the subject of many primary research publications and systematic reviews. However, there is little written about the features of academic detailing that physicians find valuable or that affect their use of it. The goal of our project was to explore family physicians' (FPs) perceptions of academic detailing and the factors that affect their use of it.     

Testing the effectiveness of the exercise plus program in older women post-hip fracture

Background: Exercise is an important strategy with potential to improve recovery in older adults following a hip fracture.Purpose: The purpose of this study was to test the impact of a self-efficacy based intervention, the Exercise Plus Program, and the different components of the intervention, on self-efficacy, outcome expectations, and exercise behavior among older women post-hip fracture.Methods: Participants were randomized to one of four groups: exercise plus, exercise only, plus only (i.e., motivation), or routine care. Data collection was done at baseline (within 22 days of fracture), 2, 6, and 12 months post-hip fracture.Results: A total of 209 women were recruited with an average age of 81.0 years (SD=6.9). The majority was White (97.1%), was widowed (57.2%), and had a high school education (66.7%). Generalized Estimating Equations were used to perform repeated measures analyses. No differences in trajectories of recovery were observed for self-efficacy or outcome expectations. A statistically significant difference in the overall trajectory of time in exercise was seen (p<.001), with more time spent exercising in all three treatment groups.Conclusions: The study demonstrated that it was possible to engage these women in a home-based exercise program and that the plus only, exercise only, and the exercise plus groups all increased exercise. Support for this project was provided by National Institute on Aging grants R37 AG09901, R01-AG18668, R01 AG17082, and the Claude D. Pepper Older Americans Independence Center P60-AG12583.     

Deltoid flap combined with fascia lata autograft for rotator cuff defects: a histologic study

The purpose of this study was to compare the histological characteristics of an autogenous fascia lata graft alone and a fascia lata graft combined with a deltoid flap in the reconstruction of rotator cuff tears. Ten New Zealand white rabbits were divided into two groups. Infraspinatus tendon defects (1 × 1 cm) were created in each animal. Reconstruction consisted of either a fascia lata graft alone or a fascia lata graft combined with a distally based deltoid flap. At 3 months, tissue harvest and histological analysis was performed. Compared to the fascia lata graft alone, there was significantly increased remodeling activity and neovascularization in the group that included a deltoid flap. Also, there was pronounced interdigitation at the graft/flap interface in the latter group. A mutually beneficial relationship may exist when an autogenous fascial graft is combined with a functional deltoid flap for reconstructing large rotator cuff defects.     

In vivo measurement of the shear modulus of the human vocal fold: interim results from eight patients

The shear modulus of the vocal fold is an essential parameter required to enhance our understanding of how the vocal fold operates, to develop mathematical models of phonatation, and to provide benchmarks to quantify the effectiveness of surgical procedures. The authors announced the successful deployment of an instrument to measure vocal fold elasticity in vivo last year, and now present the data taken from eight patients in vivo. The shear modulus was measured at the mid-membranous point, in a transverse direction with respect to the axis drawn between the anterior commissure and vocal process. The range of mean shear modulus results is 701–2,225 Pa, with a mean value of 1,371 Pa.     

A SLAP lesion associated with calcific tendinitis of the long head of the biceps brachii at its origin

Calcific tendinitis is a common condition with characteristic clinical and radiological findings. Although we do not know which condition initiated the pathologic cascade, we present a rare case of calcific tendinitis of the long head of the biceps brachii at its origin, associated with a SLAP lesion. The calcium deposit was removed and the SLAP lesion was repaired with a suture anchor arthroscopically.     

川芎嗪和参麦注射液对老龄大鼠脑缺血再灌注胃肠损伤的作用

目的 :研究川芎嗪和参麦注射液及其配伍对老龄大鼠脑缺血再灌注胃肠损伤作用。方法 :选SD 2 0～ 2 2月龄大鼠分为对照组、模型组、尼莫通组、川芎嗪组、参麦组、川芎参麦组 ,测各组脑电图幅度的变化 ,胃肠组织、血清、血液和下丘脑中的生化指标及胃肠生理变化。结果 :川芎嗪和参麦注射液对老龄大鼠脑缺血再灌注胃肠组织损伤有明显保护作用。结论 :其保护作用机制与拮抗自由基损伤、调节ATP酶活性和降低肿瘤坏死因子及调节单胺类神经递质的变化有关。川芎嗪和参麦注射液及其配伍的作用机制有所不同