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91.
Body length and occipitofrontal circumference may be good indicators of neurodevelopment in very low birthweight infants – secondary publication 下载免费PDF全文
92.
Non-penetrating trabeculectomy (NPT) is effective in preventing numerous postoperative complications encountered with trabeculectomy. Recently, NPT has been modified to further reduce intraocular pressure (IOP) by combining other techniques. However, these modified NPT methods would make the globe even weaker than NPT alone. Here, we report a case of iris prolapse caused by blunt ocular trauma after NPT with sinusotomy and mitomycin C treatment. A 68-year-old man, who underwent NPT with sinusotomy and mitomycin C treatment, suffered from blunt ocular trauma to his left eye 28 days after surgery. The iris prolapsed from the sinusotomy site. Iridectomy, scleral suturing, and pars plana vitrectomy were performed. The bleb was absent post-re-operatively. Iris prolapse occurs uncommonly following simple NPT. However, additional sinusotomy and mitomycin C treatment render the globe weaker, and iris prolapse might occur. Iris prolapse increases risks in developing secondary infections and a loss of the filtration bleb. Thus, precautions are needed postoperatively. 相似文献
93.
Kitamura Kei Shida Dai Sekine Shigeki Ahiko Yuka Nakamura Yuya Moritani Konosuke Tsukamoto Shunsuke Kanemitsu Yukihide 《International journal of clinical oncology / Japan Society of Clinical Oncology》2021,26(9):1671-1678
International Journal of Clinical Oncology - The most widely accepted staging system for colorectal cancer (CRC) is the tumor-node-metastasis (TNM) classification. In Japan, the Japanese... 相似文献
94.
Inoue H Kurosawa H Nonoyama S Imai K Kumazaki H Matsunaga T Sato Y Sugita K Eguchi M 《British journal of haematology》2002,118(4):1163-1165
We report X-linked thrombocytopenia (XLT) in a 6-year-old girl with petechiae and thrombocytopenia from the age of 3 months. Her 2-year-old brother was also diagnosed with XLT. The Wiskott-Aldrich syndrome protein (WASP) gene was detected as a replacement of +5th G to Aon intron 6 using sequence analysis, and the WASP expression levels in this patient were one-third those of a healthy control. The X-inactivation analysis of the patients lymphocytes showed a random pattern of X-chromosome inactivation. To our knowledge, this is the first confirmed report of XLT in a female. 相似文献
95.
Mayu Fukushi Keita Kinoshita Masumi Yamada Yuya Yajima Rie Utoh Minoru Seki 《RSC advances》2019,9(16):9136
Vascular tissue models created in vitro are of great utility in the biomedical research field, but versatile, facile strategies are still under development. In this study, we proposed a new approach to prepare vascular tissue models in PDMS-based composite channel structures embedded with barium salt powders. When a cell-containing hydrogel precursor solution was continuously pumped in the channel, the precursor solution in the vicinity of the channel wall was selectively gelled because of the barium ions as the gelation agent supplied to the flow. Based on this concept, we were able to prepare vascular tissue models, with diameters of 1–2 mm and with tunable morphologies, composed of smooth muscle cells in the hydrogel matrix and endothelial cells on the lumen. Perfusion culture was successfully performed under a pressurized condition of ∼120 mmHg. The presented platform is potentially useful for creating vascular tissue models that reproduce the physical and morphological characteristics similar to those of vascular tissues in vivo.A new approach for the preparation of vascular tissue models in PDMS-based composite channel structures embedded with barium salt powders. 相似文献
96.
This paper reviews the direct bonding technique focusing on the waveguide optical isolator application. A surface activated direct bonding technique is a powerful tool to realize a tight contact between dissimilar materials. This technique has the potential advantage that dissimilar materials are bonded at low temperature, which enables one to avoid the issue associated with the difference in thermal expansion. Using this technique, a magneto-optic garnet is successfully bonded on silicon, III-V compound semiconductors and LiNbO3. As an application of this technique, waveguide optical isolators are investigated including an interferometric waveguide optical isolator and a semileaky waveguide optical isolator. The interferometric waveguide optical isolator that uses nonreciprocal phase shift is applicable to a variety of waveguide platforms. The low refractive index of buried oxide layer in a silicon-on-insulator (SOI) waveguide enhances the magneto-optic phase shift, which contributes to the size reduction of the isolator. A semileaky waveguide optical isolator has the advantage of large fabrication-tolerance as well as a wide operation wavelength range. 相似文献
97.
Shibata R Ouchi N Takahashi R Terakura Y Ohashi K Ikeda N Higuchi A Terasaki H Kihara S Murohara T 《Diabetology & metabolic syndrome》2012,4(1):37-4
Background
Omentin is an adipocytokine that is abundantly expressed in visceral fat tissue. We investigated the association of omentin with the number of metabolic risk factors.Finding
The study population comprised 201 Japanese men who underwent annual health checkups. Plasma omentin levels were determined by enzyme-linked immunosorbent assay. We divided the subjects into 4 groups according to omentin levels. A reduction of plasma omentin levels significantly correlated with an increase in the mean number of metabolic risk factors such as increased waist circumference, dyslipidemia, high blood pressure and glucose intolerance.Conclusions
Circulating omentin levels negatively correlated with the multiplicity of metabolic risk factors, suggesting that omentin acts as a biomarker of metabolic disorders. 相似文献98.
Hirokazu Komatsu Satoshi Imamura Tomoki Shimizu Yuya Tsunoda Tsuyoshi Ito Jin Imai Shuichi Nagakubo Yuichi Morohoshi Yuriko Fujita 《Clinical journal of gastroenterology》2012,5(1):35-41
A 65-year-old man suffered from advanced hepatocellular carcinoma in the right lobe of the liver, for which he received no
treatment. His serum was positive for hepatitis C antibody. In spite of his poor prognosis, he remained in good clinical condition
and at 6-month follow-up the tumor had regressed without specific treatment, as assessed both radiologically and from a decrease
of a previously elevated serum tumor marker level (1st regression). The tumor regrew in size, but at 23-month follow-up could
no longer be visualized radiologically (2nd regression). A follow-up computed tomography (CT) scan did not show any relapse
of hepatocellular carcinoma until March 2005. At that time, a new lesion had developed in the caudate lobe and tumor size
had increased to ≥10 cm in diameter, and in June 2006 had invaded the portal vein and inferior vena cava. Afterwards, the
tumor lesion gradually decreased again. In June 2007, a CT scan showed a further reduction of tumor size (3rd regression).
Here, we report a rare case of spontaneous regression of hepatocellular carcinoma in which spontaneous regression and recurrence
were repeated 3 times. 相似文献
99.
Separate analysis of asialoglycoprotein receptors in the right and left hepatic lobes using Tc-GSA SPECT 总被引:1,自引:0,他引:1
Sugahara K Togashi H Takahashi K Onodera Y Sanjo M Misawa K Suzuki A Adachi T Ito J Okumoto K Hattori E Takeda T Watanabe H Saito K Saito T Sugai Y Kawata S 《Hepatology (Baltimore, Md.)》2003,38(6):1401-1409
The asialoglycoprotein receptor (ASGPR) is abundantly expressed on the sinusoidal surfaces of hepatocytes. We aimed to clarify the clinical significance of the regional distribution of ASGPRs in the human liver, especially in chronic viral hepatitis. Eighteen volunteers, 34 patients with chronic hepatitis, and 33 patients with cirrhosis (11/Child-Pugh A, 11/Child-Pugh B, 11/Child-Pugh C) were studied using a newly developed, conventional technetium-99m-diethylenetriaminepentaacetic acid-galactosyl human serum albumin ((99m)Tc-GSA), single photon emission computed tomography (SPECT) method. Using Cantlie's line as a guide, ASGPR dynamics were analyzed separately in the right and left lobes, as well as in the whole liver, using novel indices (the liver uptake ratio [LUR] and the liver uptake density [LUD], which reflect the amount and density of ASGPRs in the liver, respectively). Mean LUR and LUD values for the whole liver and the right and left lobes decreased with increasing progression of chronic viral hepatitis. The LUR for the whole liver correlated well with parameters measuring the hepatic functional reserve and the platelet count. The right LUR correlated particularly well with conventional liver function tests, and comparison of the right LUD with histologic findings showed that it was a good indicator of periportal and/or bridging necrosis and fibrosis. In conclusion, our (99m)Tc-GSA SPECT method was clinically useful in evaluating regional hepatic function and the progression of chronic viral hepatitis using dynamic changes in ASGPRs. 相似文献
100.
Kurosawa H Tsuboi T Shimaoka H Okuya M Nakajima D Matsunaga T Hagisawa S Sato Y Sugita K Eguchi M 《[Rinshō ketsueki] The Japanese journal of clinical hematology》2005,46(4):274-277
A 4-year-old boy with Down syndrome (DS) was diagnosed as having acute monoblastic leukemia (AML-M5a). Leukemic cells were CD33+, CD56+ and CD4+, with t(9;11) on cytogenetic analysis and MLL gene rearrangement. After 2 courses of induction therapy using an AML 99-Down protocol failed to obtain complete remission, the patient received cord blood transplantation from an HLA-matched donor (CBT) following a conditioning regimen comprising total body irradiation and cyclophosphamide. Only cyclosporin A was used for graft-versus-host disease prophylaxis. Stem cell transplantation may not be indicated for AML patient with DS in first remission, who display a high rate of life-threatening and fatal toxicity on therapy. This patient remained well controlled in complete remission for 4 years, representing a rare case of DS with chemotherapy-resistant AML successfully treated with a CBT. 相似文献