全文获取类型
收费全文 | 9244篇 |
免费 | 603篇 |
国内免费 | 194篇 |
专业分类
耳鼻咽喉 | 206篇 |
儿科学 | 62篇 |
妇产科学 | 59篇 |
基础医学 | 1749篇 |
口腔科学 | 180篇 |
临床医学 | 882篇 |
内科学 | 2196篇 |
皮肤病学 | 347篇 |
神经病学 | 710篇 |
特种医学 | 415篇 |
外科学 | 968篇 |
综合类 | 75篇 |
现状与发展 | 1篇 |
预防医学 | 355篇 |
眼科学 | 116篇 |
药学 | 907篇 |
中国医学 | 174篇 |
肿瘤学 | 639篇 |
出版年
2024年 | 3篇 |
2023年 | 59篇 |
2022年 | 126篇 |
2021年 | 500篇 |
2020年 | 213篇 |
2019年 | 276篇 |
2018年 | 321篇 |
2017年 | 231篇 |
2016年 | 360篇 |
2015年 | 457篇 |
2014年 | 570篇 |
2013年 | 614篇 |
2012年 | 1068篇 |
2011年 | 952篇 |
2010年 | 484篇 |
2009年 | 390篇 |
2008年 | 518篇 |
2007年 | 510篇 |
2006年 | 408篇 |
2005年 | 394篇 |
2004年 | 275篇 |
2003年 | 272篇 |
2002年 | 223篇 |
2001年 | 172篇 |
2000年 | 176篇 |
1999年 | 131篇 |
1998年 | 56篇 |
1997年 | 45篇 |
1996年 | 20篇 |
1995年 | 21篇 |
1994年 | 22篇 |
1993年 | 16篇 |
1992年 | 26篇 |
1991年 | 18篇 |
1990年 | 24篇 |
1989年 | 13篇 |
1988年 | 16篇 |
1987年 | 9篇 |
1986年 | 9篇 |
1985年 | 10篇 |
1984年 | 5篇 |
1983年 | 5篇 |
1982年 | 2篇 |
1981年 | 3篇 |
1979年 | 4篇 |
1976年 | 4篇 |
1973年 | 2篇 |
1958年 | 1篇 |
1940年 | 1篇 |
1939年 | 1篇 |
排序方式: 共有10000条查询结果,搜索用时 453 毫秒
101.
Chang Kyu Park Dong Chan Lee Chan Joo Park Jang Hoe Hwang 《Journal of Korean Neurosurgical Society》2013,54(5):423-425
We present a case report to remind surgeons of this unusual complication that can occur in any surgery, even posterior cervical spine surgery under general anesthesia and discuss its causes, treatment methods, and the follow-up results in the literature. The peripheral Tapia''s syndrome is a rare complication of anesthetic airway management. Main symptoms are hoarseness of voice and difficulty of tongue movement. Tapia''s syndrome after endotracheal general anesthesia is believed to be due to pressure neuropathy of the vagus nerve and the hypoglossal nerve caused by the endotracheal tube. To our knowledge, no report has been published or given an explanation for Tapia''s syndrome after posterior cervical spine surgery. Two patients who underwent posterior cervical surgery complained hoarseness and tongue palsy postoperatively. There is no direct anatomical relation between the operation, the vagus nerves and the hypoglossal nerves, and there is no record of displacement or malposition of the endotracheal tube. After several months, all symptoms are resolved. To avoid this problem in posterior cervical spine surgery, we suggest paying special attention to the position of the endotracheal tube to avoid excessive neck flexion before and during the positioning of the patient. 相似文献
102.
One‐hour postload plasma glucose concentration in people with normal glucose homeostasis predicts future diabetes mellitus: a 12‐year community‐based cohort study
下载免费PDF全文
![点击此处可从《Clinical endocrinology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
103.
Background
Except for the I/D polymorphism in the angiotensin I-converting enzyme (ACE) gene, there were few reports about the relationship between other genetic polymorphisms in this gene and the changes in cardiac structure and function of athletes. Thus, we investigated whether the G2350A polymorphism in the ACE gene is associated with the changes in cardiac structure and function of ball game players. Total 85 healthy ball game players were recruited in this study, and they were composed of 35 controls and 50 ball game players, respectively. Cardiac structure and function were measured by 2-D echocardiography, and the G2350A polymorphism in the ACE gene analyzed by the SNaPshot method. 相似文献104.
Yun Sung Jo Gui Se Ra Lee Narinay Kim Dong Gyu Jang Sa Jin Kim Young Lee 《International journal of medical sciences》2012,9(9):738-742
Background: The purpose of this research is to discover whether measurement of cervical length and cervical volume at term is helpful in predicting the onset of labor in VBAC candidates.Methods: Transvaginal sonographic evaluations of the cervixes of pregnant women who desired to undergo VBAC were performed between 36 - 40 weeks gestation. Clinical information such as labor onset time, gestational age at delivery and delivery mode was gathered from medical records.Results: A total of 514 pregnant women participated in this study. Cervical length was significantly longer in the group that delivered 7 days or more after measurement than in the group that delivered within 7 days of measurement (43±0.77 cm vs. 2.99±0.72 cm, p< 0.001). Cervical volume was significantly larger in the group that delivered at and after 7 days than in the group that delivered within 7 days (29.21±11.62 cm3 vs. 34.07±13.41 cm3, p=0.014). The cervical length ROC curve was significantly more predictive than the cervical volume ROC curve (AUC: 0.711 vs 0.594, p= 0.001). There were no significant differences between the combined cervical length/volume ROC curve and the cervical length ROC curve alone (p= 0.565). The AUC of the cervical length ROC curve to predict postterm pregnancy was 0.729.Conclusion: Measuring cervical length is helpful in predicting the onset of spontaneous labor within 7 days and posterm delivery in VBAC candidates. 相似文献
105.
J.‐H. Jang J.‐W. Kim S.‐H. Jeong H.‐J. Myung H. S. Kim Y. S. Park S. H. Lee J.‐H. Hwang N. Kim D. H. Lee 《Journal of viral hepatitis》2011,18(2):84-90
Summary. Clevudine has been approved for the treatment of chronic hepatitis B (CHB) in South Korea. However, its long‐term antiviral effect and safety awaits more study. The aim of this study was to evaluate antiviral efficacy, predictors of virologic response, and development of myopathy after clevudine therapy for CHB. The study included 102 nucleoside naïve CHB patients who had received clevudine for more than 6 months with good compliance. The median duration of clevudine treatment was 53 weeks (range, 25–90 weeks). A retrospective analysis of data retrieved from medical records was performed. The cumulative rate of virologic response [hepatitis B virus (HBV) DNA level <2000 copies/mL] at 48 weeks of clevudine therapy was 81%, and cumulative rate of clevudine resistance was 11% at 60 weeks of treatment. Independent predictors of virologic response to clevudine therapy were hepatitis B e antigen (HBeAg) negativity and rapid decrease of viral load during the early phase of treatment. The clevudine‐related myopathy developed in 3.9% of patients, and was reversible after discontinuation of clevudine. Clevudine showed a potent antiviral response, and its effect was higher in HBeAg‐negative patients, with rapid viral load reduction after therapy. However, long‐term therapy for more than 1 year resulted in the development of considerable resistance and myopathy. Therefore, we should consider alternative antiviral agents if clevudine resistance or clevudine‐induced myopathy is developed in patients on clevudine for the treatment of CHB. 相似文献
106.
107.
108.
Yoonjeong Jang Ah Young Lee Seung-Hee Chang Sang-Hee Jeong Kyung-Hun Park Min-Kyoung Paik 《Drug and chemical toxicology》2017,40(1):67-73
As the outermost layer of the body, the skin plays an important role in exposure to pesticides, which could have negative impacts on human health. Trifloxystrobin is a widely used fungicide of the strobilurin class, however, there is little information regarding the skin contact-associated toxic mechanism. Therefore, the present study was performed in order to identify the skin toxicity mechanism of trifloxystrobin using HaCaT (keratinocyte of human skin) cells. Following 24 or 48?h treatment, cell viability, and subsequent Annexin V-FITC/propidium iodide assay, TUNEL assay and Western blotting were performed to investigate the cell death mechanism of trifloxystrobin. Exposure to trifloxystrobin resulted in diminished viability of HaCaT cells in both a time- and concentration-dependent manner. The cell death was derived through apoptotic pathways in the HaCaT cells. Furthermore, we explored the effect of trifloxystrobin on TRAIL-mediated extrinsic apoptosis using siRNA transfection. Knockdown of death receptor 5 suppressed trifloxystrobin-provoked apoptosis. These results indicate that trifloxystrobin induces TRAIL-mediated apoptosis and has an inhibitory effect in keratinocytes that can interfere with the barrier function and integrity of the skin. This could be proposed as a mechanism of skin toxicity by trifloxystrobin and considered in the management of pesticide exposure. 相似文献
109.
110.
Jang Yuri Choi Eun Young Yoon Hyunwoo Park Nan Sook Chiriboga David A. Kim Miyong T. 《Journal of immigrant and minority health / Center for Minority Public Health》2021,23(4):689-698
Journal of Immigrant and Minority Health - Guided by the models of health assessment and social determinants of health, we examined predictors of self-rated physical, mental, oral, and cognitive... 相似文献