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21.
Oswens Siu Hung Lo Wai Lun Law Hok Kwok Choi Yee Man Lee Judy Wai Chu Ho Chi Leung Seto 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2007,392(2):173-178
OBJECTIVES: The study aimed to review the etiologies of patients who underwent surgery for small bowel obstruction (SBO) and to evaluate the risk factors affecting the early postoperative outcomes. MATERIALS AND METHODS: A case series of 430 patients (252 men) with a mean age of 64.5 years, who underwent 437 operations for SBO, were retrospectively reviewed. RESULTS: Peritoneal adhesions and hernia were the most common causes of SBO, contributing 42.3 and 26.8% of all cases, respectively. Strangulation occurred in 27.7% and caused nonviable bowel in 13.0% of obstructing episodes. Old age (age >/= 70 years), female patient, nonadhesive obstruction, and hernia were the independent significant factors associated with bowel strangulation. The 30-day mortality was 6.5%, and the median postoperative hospital stay was 8 days. Old age, the presence of premorbid pulmonary disease, and malignant obstruction were the independent factors associated with operative mortality. The overall complication rate was 35.5%, and old age was the only significant factor associated with postoperative complications. CONCLUSIONS: Surgery for SBO is still associated with significant mortality and morbidity. As old age is significantly associated with an increased incidence of strangulation, operative mortality, and complications, this group of patients should be managed with extra cautions to avoid unfavorable outcome of surgery. 相似文献
22.
V-Y肌腱瓣修补术治疗陈旧性跟腱断裂 总被引:15,自引:2,他引:13
目的 研究V—Y肌腱瓣修补术治疗陈旧性跟腱断裂的手术方法及结果。方法 对9例平均112d的陈旧性跟腱断裂患,采用小腿三头肌V—Y肌腱瓣修补术治疗修补缺损为3.2~6cm,平均4.6cm。结果 平均随访2年8个月,按Arner-Lindholm疗效评定标准评估,优7例(77.8%),良2例(22.2%),优良率为100%。结论 对于陈旧性跟腱断裂,小腿三头肌V—Y肌腱瓣修补术足一种方法简单、疗效满意的手术方法。 相似文献
23.
Man Bok Jeong Kristina Narfström Shin Ae Park Je Min Chae Kang Moon Seo 《Documenta ophthalmologica. Advances in ophthalmology》2009,119(2):79-88
The objective of this study is to compare the effects of three different anesthetic combinations on the electroretinogram
in the same animals under similar laboratory conditions. Thiopental–isoflurane (TI), medetomidine–ketamine (MK), and xylazine–ketamine
(XK) were used on each of 12 healthy miniature schnauzer dogs (MS) with a period of at least 3 weeks in between subsequent
anesthesia protocols, using the Dog Standard Protocol. The scotopic ERGs consisted of scotopic low stimulus strength (S) responses
designated S1, S2, S3, S4, and S5, at 1, 5, 10, 15, and 20 min after dark adaptation, respectively, and scotopic standard
stimulus strength (S-ST) responses. The photopic ERGs consisted of a photopic single flash (P) response and 31 Hz flicker
(P-FL) responses. For S-ST (2.5 cd s/m2), the amplitude of the a-wave using TI was significantly lower than that using MK (adjusted P = 0.05) and XK (adjusted P = 0.03), and the implicit time of the a-wave was significantly shorter than that using MK (adjusted P = 0.04). For P (2.5 cd s/m2), the amplitude of the b-wave using XK was significantly higher than that using MK (adjusted P = 0.01). The implicit times of the b-wave using TI was significantly longer and shorter than that of MK for S1, S2 and P-FL
and for S4 and S-ST, respectively, and than that of XK for S2 and P-FL and for S5 and S-ST, respectively. The results of the
present study showed that TI affected both the amplitude and the implicit time of the a-wave for S-ST and the implicit time
of the b-wave relatively more so than was the case when using XK or MK. Therefore, it appears that either XK or MK could be
advantageous to use rather than TI for clinical studies. 相似文献
24.
Three patients who presented with scrotal swelling within a few days of inguinal herniorrhaphy are reported. Ultrasonography scans performed in these patients all demonstrated features suspicious of recurrence of hernia. One patient underwent surgical exploration, which revealed only a scrotal haematoma without evidence of recurrent hernia. The other two patients were managed conservatively because clinically the swellings were regarded to be more compatible with haematoma. Both patients had subsequent resolution of the scrotal swelling with no clinical evidence of recurrence of hernia on follow‐up. It is concluded that sonographic diagnosis of recurrence of hernia shortly after inguinal herniorrhaphy can occasionally be misleading. 相似文献
25.
Brca2 is coordinately regulated
with Brca1 during proliferation and
differentiation in mammary epithelial cells 下载免费PDF全文
JayantV. Rajan Man Wang SandraT. Marquis LewisA. Chodosh 《Proceedings of the National Academy of Sciences of the United States of America》1996,93(23):13078-13083
We have analyzed the expression of the breast cancer susceptibility gene, Brca2, in mammary epithelial cells as a function of proliferation and differentiation. Our results demonstrate that Brca2 mRNA expression is tightly regulated during mammary epithelial proliferation and differentiation, and that this regulation occurs coordinately with Brca1. Specifically, Brca2 mRNA expression is up-regulated in rapidly proliferating cells; is down-regulated in response to serum deprivation; is expressed in a cell cycle-dependent manner, peaking at the G1/S boundary; and is up-regulated in differentiating mammary epithelial cells in response to glucocorticoids. In each case, an identical pattern of expression was observed for Brca1. These results indicate that proliferative stimuli modulate the mRNA expression of these two breast cancer susceptibility genes. In addition, the coordinate regulation of Brca1 and Brca2 revealed by these experiments suggests that these genes are induced by, and may function in, overlapping regulatory pathways involved in the control of cell proliferation and differentiation. 相似文献
26.
27.
女性膀胱颈部梗阻的诊断与治疗 总被引:17,自引:0,他引:17
为探讨女性膀胱颈部梗阻的病因、诊断及治疗方法。总结1981年5月~1996年6月收治女性膀胱颈部梗阻病例32例。29例经手术治疗,其中2例行膀胱颈YV成形术,27例经尿道膀胱颈部后唇切除术,效果满意。结果认为,女性膀胱颈部梗阻病因为纤维组织增生和慢性炎症所致;尿流率检查是客观评价排尿状况的指标;膀胱镜检查为可靠的诊断手段;经尿道膀胱颈部后唇切除为有效的治疗方法。 相似文献
28.
白藜芦醇甙对内毒素刺激小鼠腹腔巨噬细胞产生TNFα和NAG的影响 总被引:11,自引:0,他引:11
收集小鼠腹腔巨噬细胞,调整细胞浓度为5×10 ̄5/ml,加入24孔培养板每孔1ml,内毒素刺激前后不同时间加入白藜芦醇甙培养,检测上清中肿瘤坏死因子,溶酶体酶(N-乙酰-β-D氨基葡萄糖苷酶NAG)的变化,结果说明:白藜芦醇甙可减少上清中TNF_α和NAG的量,通过此可减少内毒素刺激产生的由TNF_α和NAG介导的组织损伤。 相似文献
29.
30.
目的比较人工关节置换术与AO加压空心螺钉术治疗老年人有移位股骨颈骨折的疗效。方法将1995年5月~2004年11月我院收治的78例年龄在65周岁以上的有移位的新鲜股骨颈骨折患者进行回顾性研究,将病例分为A、B两组,A组为人工关节置换组,B组为AO加压空心螺钉治疗组。AO加压空心螺钉治疗组(内固定组)随访12~91个月,平均41.7个月,随访人工关节置换组12~96个月,平均40.3个月。结果按Harris评分标准,A组术后优良率达到82.9%;B组内固定组优良率57.1%。术后远期并发症的发生率A组为19.5%;B组为42.9%。结论人工关节置换术和A0加压空心螺钉均是治疗老年股骨颈骨折的有效方法,但人工关节置换术可提高老年人的生活质量,减低术后并发症的发生率,所以人工关节置换的效果优于AO加压空心螺钉。 相似文献