The relationship between the migration process and speciation distribution of Cr is important for the risk assessment in the underground environment. In this work, soil columns were collected from the chromate production site, with a 40-year operation, in the groundwater depression cone area of North China plain. The relationship between chromium pollution features and the geochemical properties of soil was established, and the migration risk of Cr(VI) was assessed based on the Nemerow composite index and Hydrus-1D model. The maximum total Cr concentration in the chromium slag dumping site reached 907 mg/kg, and that in the chromate production workshop was more than 200 mg/kg across the depth. The migration of Cr might be accelerated in the soil with abundant Mn (236–1461 mg/kg) but scarce organic matters (<?0.45%). The Hydrus simulation indicated that Cr(VI) would reach a cumulative flux of 300–729 mg/cm2 after 50 years.
Bulletin of Environmental Contamination and Toxicology - Heavy metals pollution and salinization of soils are widely distributed in agricultural soils. This study investigated the effects of five... 相似文献
目的:探究生物钟相关基因在原发性肝细胞癌(简称肝癌)中的表达及意义。方法:从美国癌症和肿瘤基因图谱数据库(The Cancer Genome Atlas,TCGA)中下载肝癌数据424例,包括374例肝癌患者样本及50例正常对照样本。运用DECenter软件对51个生物钟相关基因进行差异表达分析,比较生物钟基因在肝癌患者及正常样本之间的表达情况。运用DAVID在线工具分析差异基因的GO及KEGG功能富集通路,并通过STRING数据库构建差异基因之间蛋白质相互作用网络。了解生物钟基因肝癌发生发展过程中的主要作用。结果:在374例肝癌患者样本的51个生物钟相关基因中,有21个基因在肝癌样本中表达上调(P<0.05),3个基因表达下调(P<0.05)。生物钟基因高表达样本主要富集于Wnt信号通路、Hedgehog信号通路及Hippo信号通路(P<0.001)。参与调节昼夜节律和细胞代谢的10个生物钟基因在蛋白质相互作用网络中相关性最为紧密(P<0.001)。GO分析差异基因集中作用于调节昼夜节律、细胞代谢过程、基因表达等通路(P<0.001)。结论:生物钟相关基... 相似文献