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61.
A R Wright P T English H M Cameron J B Wilsdon 《Acta radiologica (Stockholm, Sweden : 1987)》1992,33(6):582-587
Pelvimetry remains a useful technique as part of the assessment of the term breech pregnancy where vaginal delivery is planned. MR pelvimetry is accurate, well tolerated and shows soft-tissue structures as well as bone. It avoids the potentially carcinogenic effects of ionising radiation and is thought to be completely safe for mother and fetus. A technique of MR pelvimetry is described which uses gradient-echo sequences. This quick, practical method makes minimal inroads into valuable scanning time, and may therefore be considered a potentially cost-effective alternative to conventional pelvimetry. 相似文献
62.
Sneyd J. R.; Wright PMC.; Cross M.; Thompson P.; Voortman G.; Weideman M. M.; Andrews CJH.; Daniell C. J. 《British journal of anaesthesia》1997,79(4):427-432
Ten male volunteers received a 1-min i.v. infusion of a new water soluble
steroid anaesthetic agent, ORG 21465. Individuals received doses ranging
from 0.8 to 1.8 mg kg-1. All subjects experienced venous pain at the site
of injection; those receiving 1.0 mg kg-1 or more became anaesthetized.
There was no evidence of histamine release and apnoea did not occur.
Excitatory phenomena were observed in all subjects and were dose related;
no spikes were seen on the EEG. Pharmacokinetic analysis supported a
three-compartment (non-weight- related) model with compartmental volumes
V1, V2 and V3 of 4.31, 14.2 and 89.4 litre, respectively. Clearance from
the central compartment V1 was 1.55 litre min-1. Inter-compartmental
clearances Q1 and Q2 were 2.54 and 1.79 litre min-1. We found that ORG
21465 was an effective anaesthetic in humans. The relationship between
sedation, anaesthesia and excitation requires further exploration.
相似文献
63.
K L Dawson-Falk A M Wright B Bakker P T Pitlick D M Wilson R G Rosenfeld 《Australasian radiology》1992,36(3):204-209
Forty patients with karyotypically proven Turner syndrome were prospectively studied using magnetic resonance imaging (MRI) and echocardiography in order to determine the frequency of cardiovascular anomalies and to assess the utility of both imaging modalities as methods for cardiovascular evaluation in Turner syndrome. Cardiovascular anomalies were found in 45% of patients. A high absolute prevalence of bicuspid aortic valve (17.5%) and aortic coarctation (12.5%) were observed relative to comparable series. Of clinically significant abnormalities, three of five aortic coarctations and four of five ascending aortic dilatations were solely MRI detected and not evident at echocardiographic examination. MRI is thus seen as a valuable adjunct to echocardiography in the cardiovascular evaluation of Turner syndrome patients. The usefulness of MRI primarily relates to its ability to provide excellent visualisation of the entire thoracic aorta where a large proportion of clinically significant anomalies occur in Turner syndrome. 相似文献
64.
A case of intentional overdose with 18 'Ecstasy' tablets is described. 'Ecstasy' is a semi-synthetic hallucinogenic amphetamine and acute adverse reactions follow from the effects of sympathetic stimulation. To our knowledge this is the first reported case of massive intentional overdose reported in the literature. 相似文献
65.
Deoxyribonucleic acid amplification and hybridisation in Crohn''s disease using a chlamydial plasmid probe. 总被引:1,自引:1,他引:0 下载免费PDF全文
The possibility that Crohn's disease is caused by infection with Chlamydia trachomatis was examined by probing for chlamydial plasmid deoxyribonucleic acid (DNA) in DNA extracts from Crohn's disease tissue and by means of a serological study. Gut DNA extracts were obtained from 10 patients with Crohn's disease and four control subjects and were probed with a chlamydial plasmid probe after Southern blotting. The polymerase chain reaction was also used to amplify any chlamydial plasmid DNA present in tissue DNA extracts, before Southern blotting and probing. Chlamydial proctitis control specimens were not available: gut DNA extracts mixed with traces of chlamydia plasmid served as positive controls. Using these techniques, no chlamydial plasmid DNA sequences were found in Crohn's disease tissue. An enzyme linked immunosorbent assay for C trachomatis LI was performed on 48 patients with Crohn's disease and 48 control subjects. Seropositivity was present in 14.6% of patients and 29% of control subjects and was not statistically significant (p greater than 0.05). The failure to show chlamydial DNA and the lack of serological response to chlamydia make C trachomatis infection a very unlikely factor in the pathogenesis of Crohn's disease. 相似文献
66.
67.
Because of the recent rapid increase in the number of knee injuries related to racquet sports, the authors undertook a retrospective study of such injuries seen over a 5-year period at the Toronto Western Hospital Sports Medicine Institute. The 121 patients who presented over the study period with a racquet-sports-related knee injury requiring arthroscopy represented 30% of all racquet-sports related injuries seen during that period. The mean age at presentation was 32.8 years and two-thirds of the patients were men. All the major racquet sports were represented. In all, 213 lesions (7 bilateral) were seen at 128 arthroscopies, and 165 arthroscopic procedures were performed. The most common lesion was meniscal followed by chondromalacia patellae, anterior cruciate ligament tears, chondral lesions and pathologic plicae. Over 90% of the patients returned to their chosen racquet sport within 3 months of the arthroscopy and most were playing at a similar performance level to that before the initial injury. 相似文献
68.
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70.
Sylvie Naar-King Kathryn Wright Jeffrey T Parsons Maureen Frey Thomas Templin Phebe Lam Debra Murphy 《AIDS education and prevention》2006,18(1):1-11
This study piloted a brief individual motivational intervention targeting multiple health risk behaviors in HIV-positive youth aged 16-25. Interviews about sexual behavior and substance use and viral load testing were obtained from 51 HIV-positive youth at baseline and post intervention. Youth were randomized to receive a four-session motivational enhancement intervention (N = 25) or to a wait-list control (N = 26). Of the eligible youth approached, 88% agreed to participate, and 80% percent of participants completed at least three of four sessions. The treatment group showed significantly greater reductions in unprotected sex acts and in viral load compared with controls. Although change scores for substance use were not significantly different between the two groups, paired t tests demonstrated that reductions in alcohol use and marijuana use were significant for the treatment group at the trend level. There were no significant differences in substance use from baseline to posttest for the control group. Findings demonstrate the potential of a brief motivational enhancement intervention to improve health risk behaviors in HIV-positive youth. Larger randomized clinical trials are warranted. Resources required for retention should not be underestimated. 相似文献