全文获取类型
收费全文 | 8986篇 |
免费 | 910篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 66篇 |
儿科学 | 210篇 |
妇产科学 | 216篇 |
基础医学 | 1415篇 |
口腔科学 | 160篇 |
临床医学 | 1202篇 |
内科学 | 1712篇 |
皮肤病学 | 181篇 |
神经病学 | 630篇 |
特种医学 | 476篇 |
外科学 | 1137篇 |
综合类 | 129篇 |
一般理论 | 6篇 |
预防医学 | 926篇 |
眼科学 | 118篇 |
药学 | 558篇 |
中国医学 | 7篇 |
肿瘤学 | 759篇 |
出版年
2021年 | 122篇 |
2020年 | 82篇 |
2019年 | 157篇 |
2018年 | 148篇 |
2017年 | 124篇 |
2016年 | 130篇 |
2015年 | 135篇 |
2014年 | 197篇 |
2013年 | 309篇 |
2012年 | 432篇 |
2011年 | 458篇 |
2010年 | 251篇 |
2009年 | 251篇 |
2008年 | 422篇 |
2007年 | 423篇 |
2006年 | 414篇 |
2005年 | 423篇 |
2004年 | 407篇 |
2003年 | 381篇 |
2002年 | 317篇 |
2001年 | 261篇 |
2000年 | 291篇 |
1999年 | 261篇 |
1998年 | 100篇 |
1997年 | 111篇 |
1996年 | 92篇 |
1995年 | 85篇 |
1994年 | 84篇 |
1993年 | 72篇 |
1992年 | 212篇 |
1991年 | 222篇 |
1990年 | 177篇 |
1989年 | 167篇 |
1988年 | 168篇 |
1987年 | 139篇 |
1986年 | 156篇 |
1985年 | 140篇 |
1984年 | 109篇 |
1983年 | 90篇 |
1982年 | 66篇 |
1981年 | 72篇 |
1979年 | 80篇 |
1978年 | 87篇 |
1977年 | 78篇 |
1976年 | 78篇 |
1975年 | 72篇 |
1974年 | 92篇 |
1973年 | 80篇 |
1972年 | 68篇 |
1971年 | 66篇 |
排序方式: 共有9908条查询结果,搜索用时 0 毫秒
91.
S. Thomas E. Aldlyami S. Gupta M. R. Reed S. D. Muller P. F. Partington 《Archives of orthopaedic and trauma surgery》2011,131(4):455-458
Introduction
Any increase in perforations in surgical gloves is a concern. We conducted a prospective study to find a clinically acceptable brand of latex-free gloves suitable for orthopaedic surgery. 相似文献92.
Peri-articular knee fractures in osteoporotic or osteoarthritic bone present a challenge to fixation, mobilisation or non-operative management. We present a series of 15 proximal tibial and 11 distal femoral fractures treated with total knee arthroplasty at over mean follow-up period of 38.8 months. The mean age of the patients was 80 years. The choice of the implant and level of constraint was determined as per the nature of injury and preference of the surgeon dealing with the fracture. Patients were allowed rapid mobilisation with immediate full weight-bearing. Good clinical results were achieved with fracture healing, sound fixation and well-aligned flexible knees. Mean Knee Society knee score was 90.2; Knee Society function score was 35.5; Oxford Knee score was 39.5; and Short Form (SF)-36 physical function score was 37.3 and mental score 50.6. Good correlation was noted between Knee society knee score and SF-36 physical function score (Pearson's 0.76, p = 0.001), suggesting that generic health would dictate the final function achieved, whilst high knee scores suggest the satisfactory results of the operation. Analogous to arthroplasty for hip fractures, this technique should be considered as a treatment option in elderly peri-articular knee fractures with osteoporosis and/or osteoarthritis. 相似文献
93.
Hemming AW Cattral MS Reed AI Van Der Werf WJ Greig PD Howard RJ 《Annals of surgery》2001,233(5):652-659
OBJECTIVE: To analyze patient and tumor characteristics that influence patient survival to select patients who would most benefit from liver transplantation. SUMMARY BACKGROUND DATA: The selection of patients with hepatocellular carcinoma (HCC) for liver transplantation remains controversial. METHODS: One hundred twelve patients with nonfibrolamellar HCC who underwent a liver transplant from 1985 to 2000 were reviewed. Survival was calculated using the Kaplan-Meier method, with differences in outcome assessed using the log-rank procedure. Multivariate analysis was then performed using a Cox regression model. RESULTS: Overall patient survival rates were 78%, 63%, and 57% at 1, 3, and 5 years, respectively. Patients infected with the hepatitis B virus had a worse 5-year survival than those who were not (43% vs. 64%), with most deaths being attributed to recurrent hepatitis B. However, patients with hepatitis B virus who underwent more recent transplants using antiviral therapy fared as well as those who were negative for the virus, showing a 5-year survival rate of 77%. Patients with vascular invasion by tumor had a worse 5-year survival than patients without vascular invasion (33% vs. 68%). Vascular invasion, tumor size greater than 5 cm, and poorly differentiated tumor grade were predictors of tumor recurrence by univariate analysis; however, only vascular invasion remained significant on multivariate analysis: the rate of tumor recurrence at 5 years was 65% in patients with vascular invasion and only 4% for patients without vascular invasion. CONCLUSIONS: For well-selected patients with HCC, liver transplantation in the current era can achieve equivalent results to transplantation for nonmalignant indications. Vascular invasion is an indicator of high risk of tumor recurrence but is difficult to detect before transplantation. 相似文献
94.
J.D. Schold T.R. Srinivas G. Guerra A.I. Reed R.J. Johnson I.D. Weiner R. Oberbauer J.S. Harman A.W. Hemming H.U. Meier-Kriesche 《American journal of transplantation》2007,7(3):550-559
Research suggests that end-stage renal disease patients with elevated body mass index (BMI) have superior outcomes on dialysis. In contrast, low and high BMI patients represent the highest risk cohorts for kidney transplant recipients. The important question remains concerning how to manage transplant candidates given the potentially incommensurate impact of BMI by treatment modality. We conducted a retrospective analysis of waitlisted and transplanted patients in the United States from 1990 to 2003. We constructed Cox models to evaluate the effect of BMI on mortality of waitlisted candidates and identified risk factors for rapid weight change. We then assessed the impact of weight change during waitlisting on transplant outcomes. Decline in BMI on the waiting list was not protective for posttransplant mortality or graft loss across BMI strata. Substantial weight loss pretransplantation was associated with rapid gain posttransplantation. The highest risk for death was among listed patients with low BMI (13-20 kg/m(2), adjusted hazard ratio = 1.47, p < 0.01). Approximately one-third of candidates had a change in BMI category prior to transplantation. While observed declines in BMI may be volitional or markers of disease processes, there is no evidence that candidates have improved transplant outcomes attributable to weight loss. Prospective trials are needed to evaluate the efficacy of weight loss protocols for candidates of kidney transplantation. 相似文献
95.
Rolf D. Burghardt John G. Anderson Rob A. Reed John E. Herzenberg 《Journal of children's orthopaedics》2014,8(2):193-201
Purpose
Plaster casts can cause burns. Synthetic casts do not. Composite plaster–synthetic casts have not been thoroughly evaluated. This study analyzed the temperature from plaster casts compared with composite casts in a variety of in vitro conditions that would simulate clinical practice.Methods
A Pyrex cylinder filled with constant body temperature circulating water simulated a human extremity. Circumferential casts, of either plaster or composite construction (plaster inner layer with outer synthetic layer), were applied to the model. Peak temperatures generated by the exothermic reactions were studied relative to the following variables: dip water temperature (24 °C versus 40 °C), cast thickness (16, 30, and 34 ply), and delayed (5-min) versus immediate application of the synthetic outer layers. Peak temperatures from the all-plaster casts were compared with the composite casts of the same thickness. Finally, the relative cast strength was determined.Results
Potentially dangerous high temperatures were measured only when 40 °C dip water was used or when thick (30- or 34-ply) casts were made. Cast strength increased with increasing cast thickness. However, the presence of synthetics in the composite casts layers did not increase cast strength in every case.Conclusion
When applying composite casts, the outer synthetic layers should be applied several minutes after the plaster to minimize temperature rise. Composite casts do not routinely generate peak temperatures higher than plaster casts of similar thickness. Because the skin of children and the elderly is more temperature-sensitive than average adult skin, extra care should be taken to limit the exothermic reaction when casting children and the elderly: clean, room temperature dip water, minimal required cast thickness, avoidance of insulating pillows/blankets while the cast is drying. 相似文献96.
Nicole K. Roberts Reed G. Williams Cathy J. Schwind John A. Sutyak Christopher McDowell David Griffen Jarrod Wall Hilary Sanfey Audra Chestnut Andreas H. Meier Christopher Wohltmann Ted R. Clark Nathan Wetter 《American journal of surgery》2014
Background
Communication breakdowns and care coordination problems often cause preventable adverse patient care events, which can be especially acute in the trauma setting, in which ad hoc teams have little time for advanced planning. Existing teamwork curricula do not address the particular issues associated with ad hoc emergency teams providing trauma care.Methods
Ad hoc trauma teams completed a preinstruction simulated trauma encounter and were provided with instruction on appropriate team behaviors and team communication. Teams completed a postinstruction simulated trauma encounter immediately afterward and 3 weeks later, then completed a questionnaire. Blinded raters rated videotapes of the simulations.Results
Participants expressed high levels of satisfaction and intent to change practice after the intervention. Participants changed teamwork and communication behavior on the posttest, and changes were sustained after a 3-week interval, though there was some loss of retention.Conclusions
Brief training exercises can change teamwork and communication behaviors on ad hoc trauma teams. 相似文献97.
BACKGROUND: Lung cancer is the leading cause of cancer mortality in the United States. Stage-specific survival is well documented in national data sets; however, there remains limited recording of longitudinal survival in individual centers. METHODS: The VistA Surgery Package was employed to list operations performed by the thoracic surgery service at one Veterans Administration (VA) Medical Center. RESULTS: During a period of 107 months, 416 thoracic operations were performed, 211 of them for lung cancer. Stage distribution was 66% stage I, 18% stage II, 12% stage III, and 4% stage IV. During follow-up, 102 patients died, 57 of them from disease-specific causes. Median survival was 39 months for stage I. Disease-specific median survival was 83 months for stage I, and 5-year survival was 52% (72% for stage IA and 32% for stage IB). CONCLUSIONS: Pulmonary resection offers high disease-free survival for early-stage lung cancer. Decentralized hospital computer programming (DHCP) allows individual oncology programs to reliably measure survival. Use of this important outcome measure in quality improvement programs facilitates realistic counseling of patients and meaningful assessments of practice effectiveness. 相似文献
98.
Influence of antecedent lymphoid surgery on the odds of acquiring rheumatoid arthritis 总被引:2,自引:0,他引:2
The occurrence of rheumatoid arthritis (RA) and the extent of antecedent lymphoid surgeries was examined using case control study methods. Two hundred sixty-four patients with definite or classic RA were considered and 283 patients with rheumatic diseases presumably of nonimmunologic origin were used as controls. The odds for developing RA were found to be significantly higher for patients with multiple lymphoid surgeries (tonsillectomy and adenoidectomy or tonsillectomy and adenoidectomy plus appendectomy) and exhibited a gradient, increasing with more extensive surgery. Significant rank correlations were found in patients with RA between the age at tonsillectomy and the rheumatoid factor (RF) titer. An earlier tonsillectomy correlated with lower titers of RF. A significant decrease of serum RF titer was also seen in patients with RA subjected to tonsillectomy, adenoidectomy and appendectomy. We conclude that antecedent removal of lymphoid tissue from the tonsils, adenoids and appendix constitutes a risk factor predisposing to RA. Moreover, this risk seems related to the quantity of lymphoid tissue removed. 相似文献
99.
100.
The United Kingdom and Ireland Trauma & Orthopaedic eLogbook-An evidence base for enhancing training
The United Kingdom and Ireland Trauma and Orthopaedic (T&O) eLogbook was originally conceived over ten years ago in order to provide individual surgeon support and allow national analysis of surgical training experience. Since 2003 every trainee in T&O has been required to submit data recording their operative experience throughout the six years of higher specialist training. We describe how orthopaedic surgeons are using the evidence from the eLogbook to improve training, set operative standards and support consultant (post-specialist registration) revalidation. 相似文献