全文获取类型
收费全文 | 1340797篇 |
免费 | 99956篇 |
国内免费 | 2441篇 |
专业分类
耳鼻咽喉 | 19192篇 |
儿科学 | 40485篇 |
妇产科学 | 37547篇 |
基础医学 | 203436篇 |
口腔科学 | 39140篇 |
临床医学 | 117334篇 |
内科学 | 250207篇 |
皮肤病学 | 28292篇 |
神经病学 | 103178篇 |
特种医学 | 52043篇 |
外国民族医学 | 230篇 |
外科学 | 207728篇 |
综合类 | 32317篇 |
现状与发展 | 2篇 |
一般理论 | 390篇 |
预防医学 | 104075篇 |
眼科学 | 31941篇 |
药学 | 102478篇 |
3篇 | |
中国医学 | 2528篇 |
肿瘤学 | 70648篇 |
出版年
2018年 | 11956篇 |
2015年 | 11946篇 |
2014年 | 16814篇 |
2013年 | 25845篇 |
2012年 | 34899篇 |
2011年 | 37525篇 |
2010年 | 21741篇 |
2009年 | 20419篇 |
2008年 | 35524篇 |
2007年 | 38514篇 |
2006年 | 38581篇 |
2005年 | 37636篇 |
2004年 | 36885篇 |
2003年 | 35499篇 |
2002年 | 34375篇 |
2001年 | 57493篇 |
2000年 | 58989篇 |
1999年 | 49494篇 |
1998年 | 14277篇 |
1997年 | 12814篇 |
1996年 | 13040篇 |
1995年 | 12172篇 |
1994年 | 11603篇 |
1992年 | 40882篇 |
1991年 | 41036篇 |
1990年 | 40707篇 |
1989年 | 39347篇 |
1988年 | 36656篇 |
1987年 | 36217篇 |
1986年 | 34312篇 |
1985年 | 33201篇 |
1984年 | 25298篇 |
1983年 | 21608篇 |
1982年 | 13089篇 |
1981年 | 12078篇 |
1980年 | 11330篇 |
1979年 | 25460篇 |
1978年 | 18444篇 |
1977年 | 15486篇 |
1976年 | 14499篇 |
1975年 | 16084篇 |
1974年 | 19692篇 |
1973年 | 18768篇 |
1972年 | 18044篇 |
1971年 | 16983篇 |
1970年 | 15979篇 |
1969年 | 15436篇 |
1968年 | 14107篇 |
1967年 | 12952篇 |
1966年 | 11823篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
61.
L. Misery E. Weisshaar E. Brenaut A.W.M. Evers F. Huet S. Ständer A. Reich E. Berardesca E. Serra-Baldrich J. Wallengren D. Linder J.W. Fluhr J.C. Szepietowski H. Maibach for the Special Interest Group on sensitive skin of the International Forum for the Study of Itch 《Journal of the European Academy of Dermatology and Venereology》2020,34(2):222-229
The special interest group on sensitive skin of the International Forum for the Study of Itch previously defined sensitive skin as a syndrome defined by the occurrence of unpleasant sensations (stinging, burning, pain, pruritus and tingling sensations) in response to stimuli that normally should not provoke such sensations. This additional paper focuses on the pathophysiology and the management of sensitive skin. Sensitive skin is not an immunological disorder but is related to alterations of the skin nervous system. Skin barrier abnormalities are frequently associated, but there is no cause and direct relationship. Further studies are needed to better understand the pathophysiology of sensitive skin – as well as the inducing factors. Avoidance of possible triggering factors and the use of well-tolerated cosmetics, especially those containing inhibitors of unpleasant sensations, might be suggested for patients with sensitive skin. The role of psychosocial factors, such as stress or negative expectations, might be relevant for subgroups of patients. To date, there is no clinical trial supporting the use of topical or systemic drugs in sensitive skin. The published data are not sufficient to reach a consensus on sensitive skin management. In general, patients with sensitive skin require a personalized approach, taking into account various biomedical, neural and psychosocial factors affecting sensitive skin. 相似文献
62.
63.
64.
I Ahmad 《Annals of the Royal College of Surgeons of England》2015,97(7):481-486
Urothelial cell carcinoma (UCC) of the bladder is one of the most common malignancies, causing considerable morbidity and mortality worldwide. It is unique among the epithelial carcinomas as two distinct pathways to tumourigenesis appear to exist: low grade, recurring papillary tumours usually contain oncogenic mutations in FGFR3 or HRAS whereas high grade, muscle invasive tumours with metastatic potential generally have defects in the pathways controlled by the tumour suppressors p53 and retinoblastoma. Over the last two decades, a number of transgenic mouse models of UCC, containing deletions or mutations of key tumour suppressor genes or oncogenes, have helped us understand the mechanisms behind tumour development. In this summary, I present my work investigating the role of the WNT signalling cascade in UCC. 相似文献
65.
66.
67.
F. Murina R. Felice S. Di Francesco L. Nelvastellio I. Cetin 《Gynecological endocrinology》2020,36(5):431-435
AbstractThis study is a single-center, retrospective analysis of postmenopausal women presenting with dyspareunia and vulvar pain, aiming to evaluate relative effectiveness of vestibular CO2 laser therapy as a treatment. Three monthly sessions of laser were performed to each patient and thereafter a three-months follow-up was stablished. A total number of 72 patients undergoing vestibular laser treatment were recruited from patient files in the period between 2016 and 2018. Among these, 39 women also received a concomitant treatment with ospemifene (60?mg/day) during the study period. There was a statistically significant reduction of all the symptoms in both groups up to the three month follow-up. Regarding dryness and dyspareunia, the relief tent to be more prominent in the ospemifene?+?laser group at all follow-ups and remained statistically significant at three-month follow-up. Specifically, vestibular dryness was significantly lower in the ospemifene?+?laser group compared with the laser treatment group (?87% vs???34%, respectively), and the vestibular health score started declining faster in the ospemifene?+?laser group. Although, additional research is needed to understand the mechanism of action, our data shows that a combination regimen of laser and ospemifene may improve clinical effectiveness for long-term treatment of symptoms associated with the under-recognized genitourinary syndrome of menopause. 相似文献
68.
69.
70.
José A. Lorente Pablo Cardinal-Fernández Diego Muñoz Fernando Frutos-Vivar Arnaud W. Thille Carlos Jaramillo Aida Ballén-Barragán José M. Rodríguez Oscar Peñuelas Guillermo Ortiz José Blanco Bruno Valle Pinheiro Nicolás Nin María del Carmen Marin Andrés Esteban Taylor B. Thompson 《Intensive care medicine》2015,41(11):1921-1930