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排序方式: 共有1202条查询结果,搜索用时 15 毫秒
91.
Choon Jin Ooi Ida Hilmi Rupa Banerjee Sai Wei Chuah Siew Chien Ng Shu Chen Wei Govind K Makharia Pises Pisespongsa Min Hu Chen Zhi Hua Ran Byong Duk Ye Dong Il Park Khoon Lin Ling David Ong Vineet Ahuja Khean Lee Goh Jose Sollano Wee Chian Lim Wai Keung Leung Raja Affendi Raja Ali Deng Chyang Wu Evan Ong Nazri Mustaffa Julajak Limsrivilai Tadakazu Hisamatsu Suk Kyun Yang Qin Ouyang Richard Geary Janaka H De Silva Rungsun Rerknimitr Marcellus Simadibrata Murdani Abdullah Rupert W L Leong 《Journal of gastroenterology and hepatology》2019,34(8):1296-1315
The Asia–Pacific Working Group on Inflammatory Bowel Disease was established in Cebu, Philippines, under the auspices of the Asia–Pacific Association of Gastroenterology with the goal of improving inflammatory bowel disease care in Asia. This consensus is carried out in collaboration with Asian Organization for Crohn's and Colitis. With biologic agents and biosimilars becoming more established, it is necessary to conduct a review on existing literature and establish a consensus on when and how to introduce biologic agents and biosimilars in conjunction with conventional treatments for ulcerative colitis and Crohn's disease in Asia. These statements also address how pharmacogenetics influences the treatments of ulcerative colitis and Crohn's disease and provides guidance on response monitoring and strategies to restore loss of response. Finally, the review includes statements on how to manage treatment alongside possible hepatitis B and tuberculosis infections, both common in Asia. These statements have been prepared and voted upon by members of inflammatory bowel disease workgroup employing the modified Delphi process. These statements do not intend to be all‐encompassing, and future revisions are likely as new data continue to emerge. 相似文献
92.
Purpose: This is a report of 4 patients with long gap/pure esophageal atresia, who, after an initial gastrostomy and cervical esophagostomy at birth, were treated with a new technique called fundal tube esophagoplasty.Methods: The technique consisted of mobilization of the distal esophageal stump, division of the left gastric artery, and mobilization of upper half of stomach. Both walls of the stomach were incised in the region of the fundus starting on the lesser curvature in such a way that a tube was created out of the fundus, and the native esophageal stump appears to be an extension of this neoesophagus. This neoesophagus was brought to the neck by the retrosternal route and in a second stage, esophago-esophageal anastomosis was made. Thal’s fundoplication was added in 2 cases.Results: All the stages have been completed successfully in 4 babies. They have been followed up for periods ranging from 8 to 24 months after restoration of esophageal continuity. All the children are thriving.Conclusions: Fundal tube esophagoplasty (1) serves to provide a neoesophagus of natural caliber, (2) utilizes native esophagus in reconstruction, (3) does not produce a space-occupying problem in the mediastinum, and (4) preserves the gastric reservoir function. In this early experience, it appears to fulfill all the requirements of a good esophageal substitute. 相似文献
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95.
An 11-year-old boy with degenerative leiomyopathy (DL) presented with a volvulus of the transverse colon. After derotating
the volvulus, we constructed a tube colostomy (TC) from the transverse colon. This TC has been used for the past 2 years by
the patient for regular deflation of the colon and antegrade colonic enemas (ACE). We present this as a preliminary report
of the use of the Malone ACE procedure in a patient with DL and review the relevant literature.
Accepted: 15 March 2000 相似文献
96.
97.
Patawut Bovonratwet Vineet Tyagi Taylor D. Ottesen Nathaniel T. Ondeck Lee E. Rubin Jonathan N. Grauer 《The Journal of arthroplasty》2018,33(1):178-184
Background
The number of octogenarians undergoing revision total knee arthroplasty (TKA) is increasing. However, there has been a lack of studies investigating the perioperative course and safety of revision TKA performed in this potentially vulnerable population in a large patient population. The purpose of this study is to compare complications following revision TKA between octogenarians and 2 younger patient populations (<70 and 70-79 year olds).Methods
Patients who underwent revision TKA were identified in the 2005-2015 National Surgical Quality Improvement Program database and stratified into 3 age groups: <70, 70-79, and ≥80 years. Baseline preoperative and intraoperative characteristics were compared between the 3 groups. Propensity score matched comparisons were then performed for 30-day perioperative complications, length of hospital stay, and readmissions.Results
This study included 6523 (<70 years), 2509 (70-79 years), and 957 octogenarian patients who underwent revision TKA. After propensity matching, statistical analysis revealed only higher rates of blood transfusion and slightly longer length of stay in octogenarians compared to <70 year olds. Similarly, octogenarians had only higher rates of blood transfusion and slightly longer length of stay compared to 70-79 year olds. Notably, there were no differences in mortality or readmission between octogenarians compared to younger populations.Conclusion
These data suggest that revision TKA can safely be considered for octogenarians with the observation of higher rates of blood transfusion and slightly longer length of stay compared to younger populations. Octogenarian patients need not be discouraged from revision TKA solely based on their advanced age. 相似文献98.
Candida auris is an emerging fungal pathogen responsible for nosocomial invasive infection outbreaks on five continents. Large healthcare-related outbreaks of C. auris infection and colonization have been reported from different countries. Whole genome sequence analysis identified strong phylogeographic C. auris clades specific to particular geographical areas suggesting transmission of particular clades within countries. However, the mode of transmission within the healthcare environment is not clear and is likely to be multifactorial. The emergence of C. auris is alarming because this organism can harbor or develop multidrug resistance. This explains why C. auris infections are difficult to treat. In addition, difficulties in its identification in the routine diagnostic laboratory have a significant impact on outbreak detection and management. This mini-review highlights the available literature on C. auris, with particular insight into its epidemiology and the problems caused by its antifungal resistance. 相似文献
99.
Kai Lin Jeremy D. Collins Varun Chowdhary Michael Markl James C. Carr 《The international journal of cardiovascular imaging》2016,32(7):1103-1111
The aim of the present study was to test the hypothesis that heart deformation analysis (HDA) may serve as an alternative for the quantification of regional myocardial velocity. Nineteen healthy volunteers (14 male and 5 female) without documented cardiovascular diseases were recruited following the approval of the institutional review board (IRB). For each participant, cine images (at base, mid and apex levels of the left ventricle [LV]) and tissue phase mapping (TPM, at same short-axis slices of the LV) were acquired within a single magnetic resonance (MR) scan. Regional myocardial velocities in radial and circumferential directions acquired with HDA (Vrr and Vcc) and TPM (Vr and VФ) were measured during the cardiac cycle. HDA required shorter processing time compared to TPM (2.3?±?1.1 min/case vs. 9.5?±?3.7 min/case, p?<?0.001). Moderate to good correlations between velocity components measured with HDA and TPM could be found on multiple myocardial segments (r?=?0.460–0.774) and slices (r?=?0.409–0.814) with statistical significance (p?<?0.05). However, significant biases of velocity measures at regional myocardial areas between HDA and TPM were also noticed. By providing comparable velocity measures as TPM does, HDA may serve as an alternative for measuring regional myocardial velocity with a faster image processing procedure. 相似文献
100.
Kumar S Reddy L CS Kumar Y Kumar A Singh BK Kumar V Malhotra S Pandey MK Jain R Thimmulappa R Sharma SK Prasad AK Biswal S Van der Eycken E DePass AL Malhotra SV Ghosh B Parmar VS 《Archiv der Pharmazie》2012,345(5):368-377
The interaction between leukocytes and the vascular endothelial cells (EC) via cellular adhesion molecules plays an important role in the pathogenesis of various inflammatory and autoimmune diseases. Small molecules that block these interactions have been targeted as potential therapeutic agents against acute and chronic inflammatory diseases. In an effort to identify potent intercellular cell adhesion molecule-1 (ICAM-1) inhibitors, a large number of arylalkyl ketones, benzophenones, desoxybenzoins and chalcones and their analogs (54 in total) have been synthesized and screened for their ICAM-1 inhibitory activity. The structure-activity relationship studies of these compounds identified three potent chalcone derivatives and also demonstrated the possible mechanism for their ICAM-1 inhibitory activities. The most active compound was found to be 79. 相似文献