全文获取类型
收费全文 | 3099篇 |
免费 | 203篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 92篇 |
妇产科学 | 106篇 |
基础医学 | 367篇 |
口腔科学 | 44篇 |
临床医学 | 656篇 |
内科学 | 384篇 |
皮肤病学 | 23篇 |
神经病学 | 294篇 |
特种医学 | 44篇 |
外科学 | 273篇 |
综合类 | 38篇 |
一般理论 | 2篇 |
预防医学 | 456篇 |
眼科学 | 33篇 |
药学 | 182篇 |
中国医学 | 3篇 |
肿瘤学 | 294篇 |
出版年
2023年 | 21篇 |
2022年 | 30篇 |
2021年 | 64篇 |
2020年 | 47篇 |
2019年 | 63篇 |
2018年 | 79篇 |
2017年 | 74篇 |
2016年 | 84篇 |
2015年 | 73篇 |
2014年 | 87篇 |
2013年 | 162篇 |
2012年 | 241篇 |
2011年 | 251篇 |
2010年 | 140篇 |
2009年 | 125篇 |
2008年 | 245篇 |
2007年 | 220篇 |
2006年 | 240篇 |
2005年 | 201篇 |
2004年 | 194篇 |
2003年 | 188篇 |
2002年 | 162篇 |
2001年 | 24篇 |
2000年 | 11篇 |
1999年 | 30篇 |
1998年 | 36篇 |
1997年 | 19篇 |
1996年 | 15篇 |
1995年 | 20篇 |
1994年 | 19篇 |
1993年 | 14篇 |
1992年 | 15篇 |
1991年 | 10篇 |
1990年 | 11篇 |
1989年 | 8篇 |
1988年 | 7篇 |
1987年 | 3篇 |
1986年 | 5篇 |
1985年 | 9篇 |
1984年 | 13篇 |
1983年 | 9篇 |
1982年 | 9篇 |
1981年 | 10篇 |
1980年 | 5篇 |
1979年 | 2篇 |
1976年 | 3篇 |
1975年 | 1篇 |
1974年 | 2篇 |
1971年 | 1篇 |
1964年 | 1篇 |
排序方式: 共有3306条查询结果,搜索用时 15 毫秒
61.
62.
63.
Aleece MacPhail Joseph E. Ibrahim Deirdre Fetherstonhaugh Vicki Levidiotis 《Seminars in dialysis》2015,28(5):490-496
The profile of patients on chronic dialysis has shifted. There is a growing group of older patients with comorbid dementia and ESKD, who are at risk of overuse, underuse, and misuse of dialysis. Policy is lacking to help guide treatment decisions in this group. This paper explores clinical considerations specific to patients with comorbid ESKD and dementia. These include: the impact of comorbid dementia on dialysis effectiveness and feasibility; burden of care issues that are specific to patients with dementia; and capacity, autonomy, and consent. A better understanding of these issues may help guide discussions and decision making about treatment. For some older patients with multiple comorbidities including dementia, dialysis does not provide survival or quality of life benefit compared to medical management. These patients also experience additional treatment burden due to a ‘dementia unfriendly’ environment. However, exceptions may include patients who are younger, more independent, and have fewer comorbidities. Patients with dementia are often inappropriately assumed to lack capacity to participate in treatment decision making, and are at risk of having their preferences overlooked. Many patients with mild‐to‐moderate dementia remain capable of reporting their preferences and quality of life, and should always be involved in treatment discussions where possible. 相似文献
64.
Parikh P Garg R Atiemo A Vasamreddy CR Chan V Blumenthal RS 《The American Heart Hospital Journal》2004,2(4):191-197
Metabolic syndrome is a cluster of risk factors for cardiovascular disease that include obesity, atherogenic dyslipidemia, raised blood pressure, and insulin resistance. The growing trend of obesity is associated with increased prevalence of metabolic syndrome. Optimizing diet and exercise are still the leading therapy for controlling the metabolic syndrome. Based on the current evidence, further emphasis should be placed on aggressive management of other metabolic risk factors such as high blood pressure and dyslipidemia. 相似文献
65.
Julia Menke Kerstin Amann Lorenzo Cavagna Maria Blettner Arndt Weinmann Andreas Schwarting Vicki R. Kelley 《Journal of the American Society of Nephrology : JASN》2015,26(2):379-389
A noninvasive means to predict the onset and recurrence of lupus nephritis (LN) before overt renal injury is needed to optimize and individualize treatment. Colony-stimulating factor-1 (CSF-1) is expressed by kidney tubules at the onset of LN, increases with disease progression, and spills into the circulation in lupus-prone mice. We tested the hypothesis that amplified expression of CSF-1 detected in the serum or urine correlates with intrarenal CSF-1 expression and histopathology (increased macrophage accumulation, activity indices) and clinical kidney disease activity and predicts the onset and recurrence of nephritis in patients with systemic lupus erythematosus (SLE). We found increased serum or urine CSF-1 levels in patients with cutaneous, serositis, and musculoskeletal disease; however, the increase in CSF-1 levels was far greater in LN. Moreover, an elevation in serum or urine CSF-1 levels correlated with increasing intrarenal CSF-1 expression and histopathology. By longitudinally tracking patients, we found that elevated serum CSF-1 heralded the initial onset of disease, and a rise in serum or urine CSF-1 predicted recurrences of LN before clinical evidence of glomerular dysfunction and conventional serologic measures, even in patients with other manifestations of SLE. These findings indicate that serial monitoring for a rise in serum or urine CSF-1 levels in patients with SLE reflects kidney histopathology and may predict renal disease activity and the onset and recurrence of LN more accurately than conventional laboratory measures. 相似文献
66.
Characterization of a 520 kb deletion on chromosome 15q26.1 including ST8SIA2 in a patient with behavioral disturbance,autism spectrum disorder,and epilepsy: Additional information
下载免费PDF全文
![点击此处可从《American journal of medical genetics. Part A》网站下载免费的PDF全文](/ch/ext_images/free.gif)
67.
Ayano Kelly Kathleen Tymms Maarten de Wit Susan J. Bartlett Marita Cross Therese Dawson Mary De Vera Vicki Evans Michael Gill Geraldine Hassett Irwin Lim Karine Manera Gabor Major Lyn March Sean ONeill Marieke Scholte-Voshaar Premarani Sinnathurai Daniel Sumpton Armando Teixeira‐Pinto Peter Tugwell Bart van den Bemt Allison Tong 《Arthritis care & research》2020,72(10):1410-1419
68.
69.
70.