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41.
Erwin Chiquete Jesus Alegre-Díaz Ana Ochoa-Guzmn Liz Nicole Toapanta-Yanchapaxi Carlos Gonzlez-Carballo Adrin Garcilazo-vila Rogelio Santacruz-Benitez Raúl Ramírez-Reyes Rosa María Wong-Chew Guadalupe Guerrero Max Schmulson Jaime Berumen Valeria Sandoval-Rodríguez Eduardo Ruiz-Ruiz Carlos Cantú-Brito 《Archives of Medical Science》2022,18(3):711
42.
Filippo Monelli Francesco Venturelli Lisa Bonilauri Elisa Manicardi Valeria Manicardi Paolo Giorgi Rossi Marco Massari Guido Ligabue Nicoletta Riva Susanna Schianchi Efrem Bonelli Pierpaolo Pattacini Maria Chiara Bassi Giulia Besutti 《肝癌研究(英文版)》2021,7(4):13-24
Aim: In this systematic review, guidelines on non-alcoholic fatty liver disease (NAFLD) were evaluated, aiming at a guideline synthesis focusing on diagnosis an... 相似文献
43.
Fabrizio Rao Giancarlo Garuti Michele Vitacca Paolo Banfi Fabrizio Racca Renato Cutrera Martino Pavone Marina Pedemonte Matteo Schisano Stefania Pedroni Jacopo Casiraghi Andrea Vianello Valeria A Sansone UILDM Respiratory group 《Acta myologica》2021,40(1):8
Respiratory complications are common in the patient with muscular dystrophy. The periodic clinical and instrumental respiratory evaluation is extremely important. Despite the presence in the literature of updated guidelines, patient associations often report lack of knowledge of these pathologies, particularly in peripheral hospitals. The purpose of this work, inspired by the Italian Muscular Dystrophy Association (UILDM) is to improve management of respiratory problems necessary for the management of these patients complex. To this end, the main items that the specialist can meet in the follow-up of these pathologies have been analyzed and discussed, among which the respiratory basal evaluation, the criteria of adaptation to non-invasive ventilation, management of bronchial secretions, situations of respiratory emergency, indications for tracheostomy and the subject of advance directives of treatment (DAT).Key words: respiratory failure, muscular dystrophy, cough efficacy, spirometry, polygraphy, non-invasive ventilation, arterial blood gases, cough machine, invasive ventilation, tracheostomy, mechanical ventilation 相似文献
44.
Valeria Navach Luca Salvatore Calabrese Valeria Zurlo Daniela Alterio Luigi Funicelli Gioacchino Giugliano 《Dysphagia》2011,26(2):196-199
Lipofilling is a well-established technique in reconstructive plastic surgery. It is used primarily in recontouring of the
body and face to correct post-traumatic and congenital defects. The regenerative properties of adipose tissue have allowed
the use of the lipofilling technique for the treatment of burn sequelae and irradiated breast to improve tissue quality and
elasticity. We report on the case of a patient treated with radiation therapy for a nasopharyngeal carcinoma who presented
with severe postradiation dysphagia. The lipofilling technique was successfully used to improve abnormal swallowing. The technical
details and functional outcomes are discussed. 相似文献
45.
46.
Marco Cavallini Daniele Cavaniglia Francesco Felicioni Valeria Vitale Emanuela Pilozzi Vincenzo Ziparo 《Journal of hepato-biliary-pancreatic sciences》2007,14(5):526-528
A 67-year-old woman, who had symptoms of epigastric pain and abdominal distension, was found, on endoscopy, to have a large sessile villous adenoma of the periampullary duodenum. Despite the lack of evidence of malignancy, a pancreaticoduodenectomy procedure was performed, mainly because of the tumor size and site, involving the ampulla of Vater. The presence of the carcinoma was diagnosed only in the resected specimen by definitive histology. Because there is no general consensus on the optimal surgical procedure for the treatment of villous tumors of the duodenum, especially for the early stages, the indications for the operative procedure are discussed, based on a review of the literature. 相似文献
47.
Guilarde AO Turchi MD Siqueira JB Feres VC Rocha B Levi JE Souza VA Boas LS Pannuti CS Martelli CM 《The Journal of infectious diseases》2008,197(6):817-824
BACKGROUND: Clinical manifestations of dengue vary in different areas of endemicity and between specific age groups, whereas predictors of outcome have remained controversial. In Brazil, the disease burden predominantly affects adults, with an increasing trend toward progression to dengue hemorrhagic fever (DHF) noted. METHODS: A cohort of adults with confirmed cases of dengue was recruited in central Brazil in 2005. Patients were classified according to the severity of their disease. Associations of antibody responses, viremia levels (as determined by real-time polymerase chain reaction [PCR]), and serotypes (as determined by multiplex PCR) with disease severity were evaluated. RESULTS: Of the 185 symptomatic patients >14 years of age who had a confirmed case of dengue, 26.5% and 23.2% were classified as having intermediate dengue fever (DF)/DHF (defined as internal hemorrhage, plasma leakage, manifested signs of shock, and/or thrombocytopenia [platelet count, < or =50,000 platelets/mm3]) and DHF, respectively. The onset of intermediate DF/DHF and DHF occurred at a late stage of disease, around the period of defervescence. Patients with DHF had abnormal liver enzyme levels, with a >3-fold increase in aspartate aminotransferase level, compared with the range of values considered to be normal. Overall, 65% of patients presented with secondary infections with dengue virus, with such infection occurring in similar proportions of patients in each of the 3 disease category groups. Dengue virus serotype 3 (DV3) was the predominant serotype, and viremia was detected during and after defervescence among patients with DHF or intermediate DF/DHF. CONCLUSIONS: Viremia was detected after defervescence in adult patients classified as having DHF or intermediate DF/DHF. Secondary infection was not a predictor of severe clinical manifestation in adults with infected with the DV3 serotype. 相似文献
48.
Carlsson B Hou M Giandomenico V Nilsson B Totterman TH Essand M 《The Journal of infectious diseases》2005,192(11):1912-1920
Cytomegalovirus (CMV) disease remains a severe complication in patients who have undergone transplantation. Viremia can be prevented and treated by the adoptive transfer of donor-derived CMV-directed T cells. To ensure long-term protection against CMV disease, it is important to transfer CMV antigen-specific T cells that represent both the CD8+ and the CD4+ subsets. In the present study, we used as stimulators dendritic cells (DCs) that were electroporated with in vitro-transcribed 5'-capped polyadenylated messenger RNA (mRNA) that encoded the CMV pp65 protein (i.e., pp65 mRNA). These DCs could efficiently activate CMV-directed CD8+ T cells, as assayed by tetramer staining, interferon- gamma production, and cytolytic activity. We also used DCs that were pulsed with a recombinant pp65 protein to activate CMV-directed CD4+ T cells. When DCs were comodified with pp65 mRNA and pp65 protein, large numbers of CMV-directed CD8+ and CD4+ T cells were generated simultaneously. The approach outlined in the present study can be adapted for a clinical protocol that circumvents potential virus-related biohazards and is available to all patients independently of their human leukocyte antigen haplotype. 相似文献
49.
Busca A Lovisone E Aliberti S Locatelli F Serra A Scaravaglio P Omedè P Rossi G Cirillo D Barbui A Ghisetti V Dall'Omo AM Falda M 《Hematology (Amsterdam, Netherlands)》2003,8(5):303-311
Non-myeloablative stem cell transplantation (NMT) has been increasingly used in compromised patients who would otherwise have been unable to undergo allotransplant. There is little understanding of the kinetics of immune reconstitution and its influence on infective complications following NMT. The aim of present study was to evaluate lymphocyte subset reconstitution over the first 12 months post-transplant in 15 adult patients receiving NMT with comparison to that of 30 patients grafted with a conventional hemopoietic stem cell transplantation (HSCT). NMT recipients were conditioned with fludarabine-based conditioning regimens. Peripheral blood stem cell (PBSC) was the source of stem cells in 13 NMT recipients and in 24 conventional HSCT recipients. Absolute numbers of helper (CD4+) T cells, naive (CD4+ CD45RA+) and memory (CD4+ CD45RO+) T cells as well as suppressor (CD8+) T cells, CD19+ B cells and NK cells were comparable in the two groups at all time points after transplantation. A median value of 200 CD4+ T cells/microl was achieved at 2 months post-transplant by the NMT and HSCT recipients. The CD4:CD8 ratio remained severely depressed throughout the study period. Almost all CD4+ lymphocytes expressed CD45RO antigen in the both groups of patients B lymphocytes showed low counts throughout the entire study period in both groups. Bacteremia and CMV antigenemia occurred respectively in 13 and 36% of the patients in the NMT group and in 15 and 39% of the patients in the HSCT group. Our preliminary data indicate that patients receiving a NMT have a lymphocyte reconstitution similar to that observed in patients who received a conventional HSCT. The incidence of bacteremia and CMV infection were not significantly different between the groups. Nevertheless, due to the small sample size, these results should be considered suggestive rather than definitive. 相似文献
50.
Garcia Cecilia C. Piotrkowski Bárbara Baz Plácida Poncino Daniel Benavides Javier Colombato Luis Toso María Laura Reyes Yantorno Silvina Descalzi Valeria Gondolesi Gabriel E. Fraga Cesar G. Cherñavsky Alejandra C. 《Digestive diseases and sciences》2022,67(7):3006-3016
Digestive Diseases and Sciences - Deregulation of immune response and oxidative stress contribute to nonalcoholic fatty liver disease (NAFLD) pathogenesis. Resistin is a physiological modulator of... 相似文献