Biting behavior and Plasmodium infection rates of Anopheles arabiensis from Sille, Ethiopia

The man-biting behavior and Plasmodium infection rates of anopheline mosquitoes were investigated in Sille, a hyperendemic malarious area in southern Ethiopia. Seven Anopheles species were identified from all night landing collections, conducted from 18:00 to 06:00h between October 2001 and August 2002. The predominant species was Anopheles arabiensis (55.8%), followed by Anopheles coustani (31.5%), Anopheles pharoensis (9.5%), Anopheles funestus (2.2%), Anopheles nili (0.5%), Anopheles marshallii (0.4%) and Anopheles demeilloni (0.2%). Dissection of A. arabiensis showed an average parous rate of 73.2%. A large proportion of the parous mosquitoes were caught biting in the latter part of the night. Malaria sporozoite rates were determined by ELISA for A. arabiensis, with 0.5% (4/796) infective with Plasmodium falciparum and 1.76% (14/796) with Plasmodium vivax; there were no mixed infections. From our small sample of sporozoite positives we found no association between biting behavior and sporozoite infection status.     

Estimating the prevalence of high-risk behaviors using network scale-up method in university students of Larestan in 2014

Background: University students are prone to high-risk behaviors. The present study aimed to estimate the prevalence of high-risk behaviors among university students in Larestan using network scale-up (NSU) method.

Methods: This study was conducted on 390 students of Larestan’s universities to estimate their social network and the prevalence of some high-risk behaviors, including cigarette/hookah smoking, tramadol/opium use, alcohol consumption, and pre/extra-marital sex. The data were collected using a researcher-made questionnaire. Then, the prevalence of high-risk behaviors was estimated by NSU method using the SPSS statistical software, version 19.

Results: The prevalence of cigarette smoking, hookah smoking, tramadol use, opium use, alcohol consumption, and pre/extra-marital sex was 16.44%, 22.66%, 6.93%, 4.08%, 18.79%, and 19.39%, respectively. Based on uncertainty intervals, the prevalence of all the behaviors was significantly higher in males than in females.

Conclusion: The results showed the high prevalence of high-risk behaviors in university students of Larestan. Higher estimations of high-risk behaviors in the NSU methods might be attributed to the fact that the respondents may not tell the truth when asked directly about sensitive behaviors.     

Dietary intake of fish,n-3 polyunsaturated fatty acids,and risk of inflammatory bowel disease: a systematic review and meta-analysis of observational studies

Malnutrition in an obese world was the fitting title of the 13th Federation of European Nutrition Societies (FENS) conference held in October 2019. Many in     

Indices of malnutrition in patients admitted to general medical and chest medicine wards of an Iranian teaching hospital on admission and discharge

The nutritional status of hospitalised patients is generally poor on admission and in some cases declines during their stay in hospital. The aim of this study was to assess the nutritional status of a group of hospitalised patients on admission and at discharge from a large teaching hospital in Northwestern Iran. Male and female patients, who were anticipated to stay in hospital for more than 1 week on the general medical or chest medicine ward, gave informed consent to take part in the study. One hundred and fourteen patients (53.6 ± 17.2 years, body mass index (BMI) 21.0 ± 5.7 kg/m² (mean ± standard error of the mean) were recruited to evaluate the nutritional status. Changes in bioimpedance and anthropometric markers of nutritional status were recorded. The NRS 2002 (nutritional risk screening) method was used to assess nutritional status in patients on admission and prior to discharge. Malnutrition, as assessed using NRS 2002 method, decreased during the stay of patients in hospital (2.8 ± 1.0 versus 1.8 ± 1.0, p < 0.001). This study showed that prevalence of malnutrition was as high as 63.1 % on admission to the general medical and chest wards. The nutritional status of patients was significantly changed over the period of their stay in hospital, as assessed using the NRS 2002 method, although patients lost weight due to the acute care situation.     

Abundance of follicular helper T cells in Peyer's patches is modulated by CD155

The secondary humoral immune response is characterized by plasma B cells secreting isotype‐switched and affinity‐matured antibodies. The efficient generation of plasma B cells in the GC depends on the presence of follicular helper T (T_FH) cells, a cell type thought to arise from naive CD4‐positive T cells by a hitherto unresolved differentiation pathway. Mice deficient for CD155, an adhesion receptor of the immunoglobulin superfamily, are impaired to mount a secondary humoral immune response upon oral administration of antigen, while the primary IgM response is unaffected. Here, we show that mice lacking CD155 harbor significantly reduced numbers of T_FH cells in their Peyer's patches. This was paralleled by a decreased frequency of T_FH cells in the GC. Moreover, the CD155 ligand CD226, which is involved in T‐cell activation, is down‐regulated during T_FH cell differentiation, resulting in a complete absence of CD226 on those T_FH cells residing in the GC. Concurrently, the expression of TIGIT/WUCAM, a newly discovered CD155 ligand, is induced in T_FH cells. Thus, these cells replace an activating by a putative inhibitory CD155‐binding partner during their differentiation.     

Evaluation of bone mineral loss in patients with chronic traumatic spinal cord injury in Iran

Objectives

We described the associations between demographic and injury-related factors on bone mineral density (BMD) of the spine and the hip among adult patients with chronic spinal cord injury (SCI).

Design

BMD in spinal and femoral bone sites were assessed. Multivariate analysis was performed to evaluate the relationship between anthropometric and injury-related factors with BMD. Serum level and amount of dietary intake of calcium, phosphor, and 25-hydroxy vitamin D were measured.

Setting

A referral tertiary rehabilitation center in Iran.

Participants

Patients with SCI who had no previous history of endocrine disorders and were not on specific medications entered the investigation. Those with non-traumatic SCI, pregnant, or with substance dependency were excluded as well.

Interventions

No interventions were applied.

Main study outcome measures

Dual X-ray absorptiometry was performed to estimate BMD. Body mass index was positively associated with higher femoral (P < 0.01, r = 0.56) and hip (P < 0.0001, r = 0.82) BMD only in female participants. The high prevalence of vitamin D deficiency (60%) was noticeable.

Results

Older male patients revealed lower BMD only in spinal vertebrae (P < 0.02, r = −0.21). A significant higher BMD loss in lumbar vertebras in male patients with complete spinal cord lesion (P < 0.009) was detected. Spinal reduction of BMD was more severe when the level of injury was above T6 (P < 0.02).

Conclusion

Along with the clarification of age, gender, post injury duration, and the other factors'' effect on the BMD in the SCI patients, here we have also shown the noticeable prevalence of the 25-hydoxy vitamin D deficiency in these patients which needs attention.