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Metronomic therapy can increase quality of life during paediatric palliative cancer care,but careful patient selection is essential
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Christina Eriksson Gunilla Eriksson Ulla Johansson Susanne Guidetti 《Scandinavian journal of occupational therapy》2020,27(2):142-153
AbstractBackground: Integration of research-based knowledge in health care is challenging. Occupational therapists (OTs) need to implement new research-based interventions in clinical practice. Therefore it is crucial to recognize and understand the factors of specific barriers and facilitators affecting the implementation process.Aim: To identify the key factors important for OTs during the implementation process of a complex intervention.Materials and methods: A cross-sectional study with a combination of qualitative and quantitative data in a mixed method design. Forty-one OTs and 23 managers from three county councils in Sweden, responded to a questionnaire one year after the OTs participation in a workshop to prepare for implementation of a client-centered activity of daily living intervention for persons with stroke.Results: Over 70% of the OTs benefitted from reading and discussing articles in the workshop; 60% had faith in the intervention; 69% reported usability of the intervention. High level of support from managers was reported, but less from team members. The therapists’ interaction, perceptions of own efforts and contextual influence affected the implementation process.Conclusion: The workshop context with facilitation and access to evidence, supportive organizations and teams, sufficient interaction with researchers and satisfying self-image were successful key factors when involved in research. 相似文献
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Bone marrow aspirations in oncological patients: experience from an in-house standard in paediatrics
Sauer Harald Graeber Stefan Lieser Ulla Foell Juergen 《Wiener Medizinische Wochenschrift》2019,169(3-4):82-86
Wiener Medizinische Wochenschrift - Nearly all paediatric patients require deep sedation when undergoing bone marrow aspiration (BMA). We analyzed the data from our protocols documented in... 相似文献
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Diverse taxa of cyanobacteria produce beta-N-methylamino-L-alanine, a neurotoxic amino acid
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Cox PA Banack SA Murch SJ Rasmussen U Tien G Bidigare RR Metcalf JS Morrison LF Codd GA Bergman B 《Proceedings of the National Academy of Sciences of the United States of America》2005,102(14):5074-5078
Cyanobacteria can generate molecules hazardous to human health, but production of the known cyanotoxins is taxonomically sporadic. For example, members of a few genera produce hepatotoxic microcystins, whereas production of hepatotoxic nodularins appears to be limited to a single genus. Production of known neurotoxins has also been considered phylogenetically unpredictable. We report here that a single neurotoxin, beta-N-methylamino-L-alanine, may be produced by all known groups of cyanobacteria, including cyanobacterial symbionts and free-living cyanobacteria. The ubiquity of cyanobacteria in terrestrial, as well as freshwater, brackish, and marine environments, suggests a potential for wide-spread human exposure. 相似文献