全文获取类型
收费全文 | 2669篇 |
免费 | 160篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 23篇 |
儿科学 | 86篇 |
妇产科学 | 67篇 |
基础医学 | 317篇 |
口腔科学 | 32篇 |
临床医学 | 305篇 |
内科学 | 543篇 |
皮肤病学 | 87篇 |
神经病学 | 155篇 |
特种医学 | 98篇 |
外国民族医学 | 3篇 |
外科学 | 311篇 |
综合类 | 45篇 |
预防医学 | 70篇 |
眼科学 | 25篇 |
药学 | 137篇 |
中国医学 | 12篇 |
肿瘤学 | 531篇 |
出版年
2023年 | 13篇 |
2022年 | 12篇 |
2021年 | 46篇 |
2020年 | 29篇 |
2019年 | 51篇 |
2018年 | 58篇 |
2017年 | 38篇 |
2016年 | 31篇 |
2015年 | 54篇 |
2014年 | 85篇 |
2013年 | 106篇 |
2012年 | 199篇 |
2011年 | 168篇 |
2010年 | 118篇 |
2009年 | 99篇 |
2008年 | 168篇 |
2007年 | 168篇 |
2006年 | 153篇 |
2005年 | 149篇 |
2004年 | 170篇 |
2003年 | 128篇 |
2002年 | 127篇 |
2001年 | 93篇 |
2000年 | 78篇 |
1999年 | 77篇 |
1998年 | 26篇 |
1997年 | 30篇 |
1996年 | 17篇 |
1995年 | 19篇 |
1994年 | 24篇 |
1993年 | 20篇 |
1992年 | 33篇 |
1991年 | 37篇 |
1990年 | 27篇 |
1989年 | 17篇 |
1988年 | 34篇 |
1987年 | 15篇 |
1986年 | 26篇 |
1985年 | 14篇 |
1984年 | 15篇 |
1983年 | 17篇 |
1982年 | 7篇 |
1980年 | 5篇 |
1979年 | 8篇 |
1977年 | 6篇 |
1972年 | 3篇 |
1971年 | 4篇 |
1970年 | 3篇 |
1969年 | 3篇 |
1967年 | 4篇 |
排序方式: 共有2847条查询结果,搜索用时 31 毫秒
91.
92.
Yu-Cing Juho Seng-Tang Wu En Meng Chih-Wei Tsao Tai-Lung Cha Dah-Shyong Yu Guang-Huan Sun Cheng-Ping Ma Sun-Yran Chang Shou-Hung Tang 《Urological Science》2014,25(4):137-138
For patients who are suffering from neurogenic lower urinary tract dysfunction, intermittent urinary catheterization is an efficient way to empty the bladder.1 However, the method may result in various complications. Herein we present a rare complication of extraperitoneal abscess owing to intermittent urinary catheterization in a 62-year-old male who had cervical spine injury and was treated with intermittent urethral catheterization for neurogenic lower urinary tract dysfunction. Treatment and a literature review are also described. 相似文献
93.
Bryan E. Tsao MD Mark A. Ferrante MD Asa J. Wilbourn MD Robert W. Shields JR MD 《Muscle & nerve》2014,49(5):724-727
Introduction: We report the electrodiagnostic (EDX) features of 32 patients with surgically verified true neurogenic thoracic outlet syndrome (TN‐TOS). Methods: Retrospective record review. Results: We found uniform EDX evidence of a chronic axon loss process that affected the lower portion of the brachial plexus and disproportionately involved the T1 more than the C8 sensory and motor fibers. Because of this relationship, the medial antebrachial cutaneous sensory nerve (T1) and median motor (T1 > C8) study combination was abnormal in 89%, whereas response combinations that primarily assessed the C8 fibers were less frequently affected. Conclusions: The characteristic EDX features of TN‐TOS are T1 > C8 nerve fiber involvement. A comprehensive EDX examination of the lower plexus with contralateral comparison studies is imperative to diagnose this disorder accurately. Muscle Nerve 49 : 724–727, 2014 相似文献
94.
95.
Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model 总被引:16,自引:0,他引:16
Carter AJ Aggarwal M Kopia GA Tio F Tsao PS Kolata R Yeung AC Llanos G Dooley J Falotico R 《Cardiovascular research》2004,63(4):617-624
BACKGROUND: Stent-based delivery of sirolimus (SRL) has shown reduction in neointimal hyperplasia and restenosis. The purpose of this study was to evaluate the chronic vascular response and the expression of cell cycle regulators after SRL-eluting stent implantation in a porcine coronary model. METHODS: Forty-nine pigs underwent placement of 109 oversized stents (control, n=54, SRL (140 microg/cm(2)), n=55) in the coronary arteries with histologic analysis and Western blot (PCNA, p27(kip1), CD45, MCP-1, IL-2, IL-6, TNF-beta) at 3, 30, 90 or 180 days. RESULTS: At 3 days, the mean thrombus area was similar for control (0.38+/-0.19 mm(2)) and SRL (0.29+/-0.09 mm(2)) stents. After 30 days, the mean neointimal area was significantly less for the SRL (1.40+/-0.35 mm(2)) versus the control stents (2.94+/-1.28 mm(2), p<0.001). At 90 and 180 days, the mean neointimal area was similar for the SRL (3.03+/-0.92 and 3.34+/-0.99 mm(2)) as compared with control stents (3.45+/-1.09 and 3.65+/-1.23 mm(2)). Western blot analysis demonstrated an increased expression of p27(kip1) in the vessel wall at 90 days for the SRL versus control stents (p=0.05) but with increased levels of PCNA in the SRL as compared with control stents (p=0.003). CONCLUSION: SRL-eluting stents favorably modulate neointimal formation for 30 days in the porcine coronary model. Long-term inhibition of neointimal hyperplasia is not sustained presumably due to delayed cellular proliferation despite increased levels of the cyclin-dependent kinase p27(kip1) in the vessel wall. 相似文献
96.
97.
Characteristics of the tumour that affect and predict the survival outcome of patients with cancer are prognostic markers for cancer. In non-small cell lung carcinoma (NSCLC), stage is the main determinant of prognosis and the basis for deciding options for treatment. Patients with early-stage tumour are treated by complete surgical resection, which is curative in 40-70% of patients. That there are other factors important in determining the biology of these tumours, especially genes that have a role in metastasis, is indicated. Such factors could potentially be used to further classify patients into groups according to substages that may be treated differently. During the past decade, a large number of proteins that are putatively important in carcinogenesis and cancer biology have been studied for their prognostic value in NSCLC, but none of them have been proved to be sufficiently useful in clinical diagnosis. Several markers (epidermal growth factor receptor, human epidermal growth factor receptor 2, Ki-67, p53 and Bcl-2) have been studied exhaustively. Ki-67, p53 and Bcl-2 are suggested to be important but weak prognostic markers, by meta-analyses of the results. Cyclin E, vascular endothelial growth factor A, p16(INK4A), p27(kip1) and beta-catenin are promising candidates, but require further study in large randomised clinical trial samples by using standardised assays and scoring systems. Some issues and inconsistencies in the reported studies to date are highlighted and discussed. A guideline for a multi-phase approach for conducting future studies on prognostic immunohistochemistry markers is proposed here. 相似文献
98.
JY Nagata TF Rocha‐Lima BP Gomes CC Ferraz AA Zaia FJ Souza‐Filho A De Jesus‐Soares 《Australian dental journal》2015,60(3):416-420
Immature avulsed teeth are not usually treated with pulp revascularization because of the possibility of complications. However, this therapy has shown success in the treatment of immature teeth with periapical lesions. This report describes the case of an immature replanted tooth that was successfully treated by pulp revascularization. An 8‐year‐old boy suffered avulsion on his maxillary left lateral incisor. The tooth showed incomplete root development and was replanted after 30 minutes. After diagnosis, revascularization therapy was performed by irrigating the root canal and applying a calcium hydroxide paste and 2% chlorhexidine gel for 21 days. In the second session, the intracanal dressing was removed and a blood clot was stimulated up to the cervical third of the root canal. Mineral trioxide aggregate was placed as a cervical barrier at the entrance of the root canal and the crown was restored. During the follow‐up period, periapical repair, apical closure and calcification in the apical 4 mm of the root canal was observed. An avulsed immature tooth replanted after a brief extra‐alveolar period and maintained in a viable storage medium may be treated with revascularization. 相似文献
99.
100.