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Valentina Veselinovi Saa Marin Zoran Tati Nataa Trti Olivera Doli Tijana Adamovi Radmila Arbutina Miodrag epanovi Aleksandar Todorovi 《Acta stomatologica Croatica》2021,55(4):367
ObjectivesThe aim of this study was to evaluate the influence of artificial ageing on the retention force of original semipermanent cements, as well as the possibility of using conventional cements for semipermanent cementation with adequate modification of the cementing protocol.Materials and methodsForty CoCrMo alloy crowns were divided in four groups (each group n=10) and fixed with two semipermanent cements (resin-based and glass ionomer-based cements) and one conventional (zinc phosphate), using conventional and modified cementation techniques on titanium abutments. The samples were stored in humid conditions for 24 hours at 37°C and subjected to thermocycling (500 cycles) and mechanical cyclic loading (7 days, 3, 6, 9 and 12 months function simulation). The cast crowns were removed and the retention force was recorded.ResultsThe highest initial retention force measured was for zinc-phosphate cement - conventional cementing (198,00±61,90 N), followed in descending order by zinc-phosphate cement - modified cementing technique (152,00±45,42 N), long term temporary cement – GC Fuji Temp LT (57,70±20,40 N), and semipermanent cement - Telio CS Cem Implant (56,10±18,68 N). After 12 months, the highest retention force measured was for zinc-phosphate cement - conventional cementing (88, 90±14, 45 N), followed by zinc-phosphate cement – modified cementing (48, 15±14,41N), semipermanent cement GC Fuji Temp LT (16,55±3,88 N) and Telio CS Cem Implant (15,55±5,52 N).ConclusionsZinc-phosphate cement - modified cementing technique and original semipermanent cements can be recommended for conditional permanent cementing of implant supported crowns.Clinical relevanceThe use of semipermanenet cements and zinc-phosphate cement - modified cementing technique provides a predictable retrievability of implant-supported crowns. 相似文献
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Mihaljevic Marina Zeljic Katarina Soldatovic Ivan Andric Sanja Mirjanic Tijana Richards Alexander Mantripragada Kiran Pekmezovic Tatjana Novakovic Ivana Maric Nadja P. 《European archives of psychiatry and clinical neuroscience》2017,267(6):527-539
European Archives of Psychiatry and Clinical Neuroscience - Increased reactivity to stress is observed in patients with schizophrenia spectrum disorders and their healthy siblings in comparison... 相似文献
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Tijana ?tajner Zorica Vasiljevi? Dragana Vuji? Marija Markovi? Goran Risti? Dragan Mi?i? Srdjan Pa?i? Vladimir Ivovi? Daniel Ajzenberg Olgica Djurkovi?-Djakovi? 《Journal of clinical microbiology》2013,51(8):2686-2690
In immunocompromized patients, including hematopoietic stem cell transplant (HSCT) recipients, life-threatening toxoplasmosis may result from reactivation of previous infection. We report a case of severe disseminated toxoplasmosis that developed early after allogeneic HSCT for T-cell lymphoblastic leukemia/lymphoma in a 15-year-old Toxoplasma gondii-seropositive boy with Nijmegen breakage syndrome, a rare genetic DNA repair disorder associated with immunodeficiency. The donor was the patient''s HLA-identical brother. Prophylaxis with cotrimoxazole was discontinued a day before the HSCT procedure. Signs of lung infection appeared as early as day 14 post-HSCT. The presence of tachyzoite-like structures on Giemsa-stained bronchoalveolar lavage (BAL) fluid smears suggested toxoplasmosis. Real-time PCR targeted at the T. gondii gene revealed extremely high parasite burdens in both blood and BAL fluid. Although immediate introduction of specific treatment resulted in a marked reduction of the parasite load and transient clinical improvement, the patient deteriorated and died of multiple organ failure on day 39 post-HSCT. Direct genotyping of T. gondii DNA from blood and BAL fluid with the PCR-restriction fragment length polymorphism method revealed type II alleles with SAG1, SAG2, and GRA6 markers but alleles of both type I and type II with GRA7. Additional analysis with 15 microsatellite markers showed that the T. gondii DNA was atypical and genetically divergent from that of the clonal type I, II, and III strains. This is the first report of increased clinical severity of toxoplasmosis associated with an atypical strain in the setting of immunosuppression, which emphasizes the need to diagnose and monitor toxoplasmosis by quantitative molecular methods in cases of reactivation risk. AF146527相似文献
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Medical education, training and preoperative diagnostics can be drastically improved with advanced technologies, such as virtual reality. The method proposed in this paper enables medical doctors and students to visualize and manipulate three-dimensional models created from CT or MRI scans, and also to analyze the results of fluid flow simulations. Simulation of fluid flow using the finite element method is performed, in order to compute the shear stress on the artery walls. The simulation of motion through the artery is also enabled. The virtual reality system proposed here could shorten the length of training programs and make the education process more effective. 相似文献
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Characterization of the proteasome interaction network using a QTAX-based tag-team strategy and protein interaction network analysis 总被引:1,自引:0,他引:1
Guerrero C Milenkovic T Przulj N Kaiser P Huang L 《Proceedings of the National Academy of Sciences of the United States of America》2008,105(36):13333-13338
Quantitative analysis of tandem-affinity purified cross-linked (x) protein complexes (QTAX) is a powerful technique for the identification of protein interactions, including weak and/or transient components. Here, we apply a QTAX-based tag-team mass spectrometry strategy coupled with protein network analysis to acquire a comprehensive and detailed assessment of the protein interaction network of the yeast 26S proteasome. We have determined that the proteasome network is composed of at least 471 proteins, significantly more than the total number of proteins identified by previous reports using proteasome subunits as baits. Validation of the selected proteasome-interacting proteins by reverse copurification and immunoblotting experiments with and without cross-linking, further demonstrates the power of the QTAX strategy for capturing protein interactions of all natures. In addition, >80% of the identified interactions have been confirmed by existing data using protein network analysis. Moreover, evidence obtained through network analysis links the proteasome to protein complexes associated with diverse cellular functions. This work presents the most complete analysis of the proteasome interaction network to date, providing an inclusive set of physical interaction data consistent with physiological roles for the proteasome that have been suggested primarily through genetic analyses. Moreover, the methodology described here is a general proteomic tool for the comprehensive study of protein interaction networks. 相似文献
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Goran Djuričić Zorica Milošević Tijana Radović Nataša Milčanović Predrag Djukić Marko Radulovic Jelena Sopta 《BMC medical imaging》2018,18(1):54