硒酵母中硒的化学形态分析与评价

 利用Ｔｒｉｓ－缓冲液－甘油提取法对硒酵母的化学形态进行了分析，并与透析法进行比较。结果表明，经过特殊工艺生产的硒酵母虽然总硒含量达到４０００μｇ／ｇ以上，但其中５０％以上的硒为硒蛋氨酸形态的蛋白质或其它大分子态硒，无机态硒仅占３％左右，而游离态硒只占０．０１％。说明硒酵母有广阔的开发前景，同时也为硒制剂提供了适宜的质量监测方法。     

成人脂肪组织动物移植实验研究

目的建立人类脂肪组织移植实验的动物模型,并对几种不同的脂肪移植方式进行比较和评价。方法我们引用Balb／C（nu／nu）裸鼠建立了人类脂肪组织移植实验的动物模型并将成人的脂肪小叶、真皮脂肪块和脂肪微粒分别移植于14只裸鼠背部的肉膜下,间隔5天到4个月取样进行组织学和组织化学检查。结果脂肪小叶移植后具有最好的组织学结果和体积的维持。结论裸鼠是研究人类游离脂肪移植的有效工具。对三种游离脂肪移植方式的比较研究显示出以脂肪小叶为单位进行移植的优越性,在一定程度上证实了体积／面积比率和损伤因素对游离脂肪存活的重要意义.     

Studies on plasma endothelin changes in varicocele patients

Aim: To investigate the possible role endothelin may play in the pathogenesis of varicocele and varicocele-induced infer-tility. Methods: In varicocele patients, radioimmunoassay is used to determine the blood endothelin concentration inthe spermatic vein and the antecubital vein separately. Results: The blood endothelin concentration of the spermaticvein (66.8±23.5 pg/mL) was significantly higher (P <0.05) than that of the antecubital vein (55.3±25.3 pg/mL).The endothelin concentration in the spermatic vein in Grade Ⅱ varicocele patients was not significantly different from thatin Grade Ⅲ patients ( P = 0.87). Conclusion: The higher blood endothelin level in the spermatic vein may indicate theinvolvement of endothelin in the pathophysiology of varicocele and varicocele-induced infertility. (Asian J Androl 1999Sep ; 1: 159 - 160)     

神经根切断术治疗痉挛性脑瘫

目的 研究治疗痉挛性脑瘫新的手术方法。方法 利用臂丛神经根相互代偿的原理设计了选择性臂丛神经根断术以及腰骶神经根选择性切断术治疗痉挛性脑瘫的方法,对９例病例进行治疗（上肢７例,下肢２例）结果术后９例患者肢体痉挛明显减轻,功能得到显著改善。结论 选择性神经根切断术对减轻脑瘫肢体痉挛疗效显著。     

口内入路下颌角肥大弧形截骨术

OBJECTIVE: This paper presents a new method of osteotomy for the prominent mandibular angle (PMA). METHODS: Two modifications have been made to the conventional procedures. The first is the one-stage curved osteotomy of the mandibular angle. The second is non-resection of the masseter muscle. The surgical procedure has been performed through an intraoral approach with a direct field of vision. RESULTS: From December 1996 to December 1997, a total of thirty-eight patients suffering from PMA have been operated on by this method with satisfactory results. The follow-up is 3 to 12 months. CONCLUSION: This method is a very simple and ideal procedure with much less complications for surgical treatment of PMA.     

椎管内脊膜瘤的诊断及手术治疗：———附42例报告

目的：回顾性研究４２例脊椎管内脊膜瘤的临床表现、诊断及手术治疗效果。方法：分别对椎管内脊膜瘤的部位、类型、临床表现、影像学特征和手术治疗方法进行描述。结果：３９例肿瘤全部切除,３例大部切除,术后随访３月～６年,３例复发再手术,１例术后症状加重,１例术后发生肺部感染。手术优良率达９０４８％。结论：根据临床表现、影像学特征结合病理检查能确立诊断,手术治疗是行之有效的治疗方法     

Antegrade locked nailing for humeral shaft fractures

Treatment results of antegrade locked nailing of acute humeral shaft fractures, including union rate and recovery of shoulder function, have been inconsistent. This led the current authors to hypothesize that implant design and surgical techniques might account for this inconsistency. In the current study, 47 fractures (38 acute; nine pathologic) in 47 patients achieved union with the techniques of closed nailing, short to long segment nailing, and fracture compression. Satisfactory recovery of shoulder function occurred because of minimal surgical trauma, prevention of impingement by the nail or locking screws, and prevention of axillary nerve injury or comminution of the humeral head. Forty-seven patients with 38 acute fractures and nine pathologic fractures were treated with humeral locked nails. Mean followup time was 21.4 months. With a single operation, all 38 acute fractures proceeded to eventual union; the average time to union was 7.8 weeks. Thirty-five patients had excellent or satisfactory recovery of shoulder function. Complications included slipout of the proximal screw, nail breakage, fragment displacement, and transient postoperative radial nerve palsy. All nine patients with pathologic fractures had substantial pain relief and increased arm function after surgery. The current study shows the reliability of antegrade locked nailing for proximal and middle third fractures of the humeral shaft.     

大剂量硝酸甘油介入~(99m)Tc-MIBI心肌SPECT判定存活心肌的研究

目的：探讨大剂量硝酸甘油介入（大剂量硝充法）99mTc-MIBI心肌SPECT对存活心肌判定的价值。材料和方法：对44例大剂量硝充组和31例小剂量硝充组的心肌梗塞患者均行静息和硝充法心肌显像。采用9节段评分法对两次显像进行了比较。其中两组中分别有18例和17例于冠脉血管再通术（PTCA或CABG）后半年内再次复查了静息心肌显像并与术前比较。结果：大剂量硝充组静息心肌显像灌注异常节段为154个，硝充后有77个节段呈现了再分布，总再分布率为50．0％（77／154）；小剂量硝充组静息心肌显像灌注异常节段为110个，硝充后有35个节段呈现了再分布，总再分布率为31．8％（35／110）。大剂量和小剂量组中18例和17例PTCA和CABG患者术后静息心肌显像与硝充法心肌显像比较阳性符合率分别为85．7％和68．8％．预测准确率为对71．9％和50．9％。结论：大剂量硝酸甘油介入99Tc-MIBI心肌SPECT具有较高的存活心肌检出率和预测准确性。     

P21ras和CD44在非小细胞肺癌中的表达及其意义

 目的 探讨P<'21ras>和CD44在非小细胞肺癌中表达的相关性及其在淋巴结转移中的作用.方法 应用S-P免疫组化方法检测66例非小细胞肺癌原发灶及其20例转移性淋巴结标本P<'21ras>和CD 44的表达.结果 P<'21ras>和CD 44在非小细胞肺癌原发灶中的阳性率分别为90%和85%.有淋巴结转移组P<'21ras>和CD 44的阳性表达率显著高于无淋巴结转移组(P<0.05).相关性检验提示P<'21ras>阳性组和CD44阳性组间差异有非常显著意义(P<0.01).结论 P<'21ras>和CD 44在非小细胞肺癌中的表达有明显的相关性.P<'21ras>和CD 44阳性表达可以作为非小细胞肺癌具有淋巴结转移潜能的指标.