全文获取类型
收费全文 | 3534篇 |
免费 | 264篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 86篇 |
妇产科学 | 105篇 |
基础医学 | 648篇 |
口腔科学 | 70篇 |
临床医学 | 376篇 |
内科学 | 767篇 |
皮肤病学 | 110篇 |
神经病学 | 382篇 |
特种医学 | 81篇 |
外科学 | 307篇 |
综合类 | 23篇 |
一般理论 | 3篇 |
预防医学 | 338篇 |
眼科学 | 41篇 |
药学 | 226篇 |
中国医学 | 6篇 |
肿瘤学 | 217篇 |
出版年
2024年 | 2篇 |
2023年 | 55篇 |
2022年 | 65篇 |
2021年 | 125篇 |
2020年 | 75篇 |
2019年 | 128篇 |
2018年 | 163篇 |
2017年 | 109篇 |
2016年 | 114篇 |
2015年 | 136篇 |
2014年 | 173篇 |
2013年 | 219篇 |
2012年 | 313篇 |
2011年 | 311篇 |
2010年 | 174篇 |
2009年 | 186篇 |
2008年 | 240篇 |
2007年 | 233篇 |
2006年 | 212篇 |
2005年 | 205篇 |
2004年 | 162篇 |
2003年 | 139篇 |
2002年 | 111篇 |
2001年 | 9篇 |
2000年 | 8篇 |
1999年 | 27篇 |
1998年 | 28篇 |
1997年 | 16篇 |
1996年 | 3篇 |
1995年 | 12篇 |
1994年 | 6篇 |
1993年 | 5篇 |
1992年 | 5篇 |
1991年 | 3篇 |
1990年 | 5篇 |
1989年 | 1篇 |
1988年 | 2篇 |
1987年 | 1篇 |
1986年 | 7篇 |
1985年 | 2篇 |
1984年 | 3篇 |
1983年 | 2篇 |
1980年 | 1篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1972年 | 1篇 |
1969年 | 1篇 |
1964年 | 1篇 |
排序方式: 共有3806条查询结果,搜索用时 15 毫秒
51.
Understanding the mode of action of pathogenic bacteria through in vitro studies can provide additional insight into their infection strategies. Here we have characterized the effect of Photorhabdus luminescens and Photorhabdus asymbiotica on two distinct insect cell lines. We report that insect cell survival and metabolism as well as bacterial proliferation differ between infection with two Photorhabdus species. These findings reinforce the notion that P. luminescens and P. asymbiotica deploy diverse tactics to infect insect cells. This knowledge might lead to better appreciation of the interaction between pathogenic bacteria and different types of insect cells. 相似文献
52.
Volz Kristen Wyckoff Emily Medina Tania Heudo Denmat Zeely Field Christiana LaRose Jessica Gorin Amy Leahey Tricia 《Journal of behavioral medicine》2021,44(6):853-859
Journal of Behavioral Medicine - Lower income is associated with greater stress, and stress has been shown to undermine treatment engagement and weight loss outcomes in face-to-face interventions.... 相似文献
53.
54.
Steffen Moritz Maarten J. V. Peters Frank Larøi Tania M. Lincoln 《Cognitive neuropsychiatry》2013,18(6):531-548
Introduction. Distorted metacognitive beliefs are increasingly considered in theoretical models of obsessive-compulsive disorder (OCD). However, so far no consensus has emerged regarding the specific metacognitive profile of OCD. Methods. Participants with OCD (n=55), schizophrenia (n=39), and nonclinical controls (n=49) were assessed with the Metacognitions Questionnaire (MCQ-30). Results. Except for positive beliefs about worry, both patient samples exceeded nonclinical controls on all MCQ subscales. The MCQ “need to control thoughts” and “negative beliefs about uncontrollability and danger” subscales showed strong correlations with obsessions, and scores in the former scale were elevated in hallucinators. In contrast to several prior studies, “cognitive confidence” was related neither to core OCD nor to schizophrenia symptomatology. Conclusions. Notwithstanding large pathogenetic differences between OCD and schizophrenia, findings suggest that obsessions and hallucinations may share a common metacognitive pathway. Need to control thoughts and dysfunctional beliefs about the malleability of worries may represent critical prerequisites for the two phenomena to emerge. 相似文献
55.
56.
57.
Alfredo Nunes Ferreira-Neto Tania Rodriguez-Gabella Leonardo Guimaraes Afonso Freitas-Ferraz Mathieu Bernier Camila Figueiredo Guimaraes Sergio Pasian Jean-Michel Paradis Robert Delarochellière Eric Dumont Siamak Mohammadi Dimitri Kalavrouziotis Mélanie Côté Philippe Pibarot Josep Rodés-Cabau 《Revista espa?ola de cardiología》2021,74(3):247-256
Introduction and objectivesWe assessed the long-term hemodynamic performance of transcatheter heart valve (THV) by paired transthoracic echocardiography (TTE), and the incidence, characteristics and factors associated with THV structural valve degeneration (SVD).MethodsA total of 212 patients who underwent transcatheter aortic valve replacement and had a potential follow-up > 5 years with at least 1 TTE ≥ 1-year postprocedure were included. All patients had a TTE at 1 to 5 years and 36 had another one at 6 to 10 years. SVD was defined as subclinical (increase > 10 mmHg in mean transvalvular gradient + decrease > 0.3 cm2 in valve area and/or new-onset mild or moderate aortic regurgitation) and clinically relevant (increase > 20 mmHg in mean transvalvular gradient + decrease > 0.6 cm2 in valve area and/or new-onset moderate-to-severe aortic regurgitation). Fifteen patients had a transesophageal echocardiography at the time of SVD diagnosis, and 85 an opportunistic computed tomography examination at 1 (0.5-2) years.ResultsTransvalvular mean gradient increased and valve area decreased over time (P < .01). At 8 years of follow-up, SVD occurred in 30.2% of patients (clinically relevant: 9.3%). Transesophageal echocardiography revealed thickened and reduced-mobility leaflets in 80% and 73% of SVD cases, respectively. No baseline or procedural factors were associated with SVD. THV underexpansion (3.5%) or eccentricity (8.2%) had no impact on valve hemodynamics/SVD at follow-up.ConclusionsA gradual THV hemodynamic deterioration occurred throughout a 10-year period, leading to SVD in ~30% of patients (clinically relevant in < 10%). Leaflet morphology/mobility were frequently impaired in SVD cases, but THV geometry did not influence valve hemodynamics or SVD. 相似文献
58.
Exercise Training Improves Plasma Lipid and Inflammatory Profiles and Increases Cholesterol Transfer to High‐Density Lipoprotein in Elderly Women 下载免费PDF全文
59.
Carolina Nazzal Steven Shea Cecilia Castro-Diehl Tania Alfaro Patricia Frenz Carlos J. Rodriguez 《Global Heart》2018,13(1):19-26
Background
Social determinants differ between countries, which is not always considered when adapting health policies and interventions to face inequalities in noncommunicable diseases and their risk factors.Objectives
The study sought to analyze educational inequalities in controlled blood pressure (CBP), obesity, and smoking in study populations from Chile and the United States in 2 periods, both countries with large social inequalities.Methods
The study used data from the first and fifth waves of the MESA (Multiethnic Study of Atherosclerosis) cohort, and the 2003 and 2009 to 2010 Chilean National Health Survey (CNHS) survey outcome measures. The study compared cardiovascular risk factors prevalence as well as relative index of inequality (RII) and slope index of inequality (SII) between the 2 samples.Results
In the CNHS 67.9% and 52.6% of participants had below primary education in 2003 and 2009 to 2010, respectively, compared with 12.3% and 8.1% in the first and fifth waves of the MESA study, respectively. Smoking prevalence was higher and increased in the CNHS compared with the MESA study, concentrated in better-educated women in both years (RII: 0.34; 95% confidence interval [CI]: 0.17 to 0.68; and RII: 0.55; 95% CI: 0.34 to 0.89, respectively). In contrast, smoking decreased over time in the MESA study in all socioeconomic strata, although relative inequalities increased in both sexes (for women, RII: 2.32; 95% CI 1.36 to 3.97; for men, RII: 3.34; 95% CI 2.04 to 5.47). CBP prevalence in both periods was higher in the first and fifth waves of the MESA study (69.7% and 80.2%) compared with the 2003 and 2009 to 2010 CNHS samples (34.2% and 52.3%), but only for the MESA study RII, favoring the better educated, was it significant in both periods and sexes. Obesity inequalities for Chilean women decreased slightly between 2003 and 2009 as prevalence grew in the most educated (RII: 2.21 to 1.68; SII: 0.29 to 0.22, respectively); conversely, they increased for both sexes in the MESA study.Conclusions
The study findings confirm that patterns and trends in prevalence, and absolute and relative inequalities vary by country, suggesting that context and cultural issues matters. 相似文献60.
Juan-Carlos de Vicente Tania Rodríguez-Santamarta Ignacio Pe?a Lucas Villalaín álvaro Fernández-Valle Manuel González-García 《Medicina oral, patología oral y cirugía bucal》2015,20(5):e547-e553