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41.
目的 :探讨系统性红斑狼疮 (SLE)女性患者血清肿瘤标志物CA12 5 ,CA199含量变化及临床意义。方法 :用化学发光法测定 30例正常女性和 38例SLE女性患者血清中CA12 5 ,CA199含量。结果 :正常组CA12 5含量为 11.14± 6 .4 8U/ml,CA199含量为 3.75± 2 .89U/ml;SLE组CA12 5 ,CA199分别为 2 2 .5 6± 2 0 .4 6U/ml,9.5 7± 9.34U/ml。SLE患者CA12 5 ,CA199阳性率分别为 2 1.1% ,7.89%。结论 :SLE患者血清CAl2 5 ,CA199含量较正常组增高 (P <0 .0 5 )。CA12 5 ,CA199在SLE女性患者中可出现阳性 ,对临床诊断SLE有一定价值。 相似文献
42.
43.
This study attempts to demonstrate the existence of allergic contact dermatitis from grass, and to develop a patch test series to screen patients with grass intolerance. 6 common grass species from lawns and military training areas were collected. Solvent extracts of polar. non-polar and volatile fractions were prepared and used for patch testing in 20 control subjects and 46 patients with a history of grass intolerance. The 20 control had negative responses to patch testing. 5 out of 46 patients had positive patch tests to Axonopus compressus (carpet grass). Ischaenmum muticum (sea-shore centipede grass). Imperata evlindrica (lalang). Panicum maximum (Guinea grass) and Pennisetum purpureum (elephant grass). Reactions to the non-polar fraction for all 5 species were noted. This study demonstrates the existence of allergic contact dermatitis from various common species of grass. In our series, this is seen in 11% of those with a history of grass intolerance. 相似文献
44.
Jugular foramen neuromas: a review of 14 cases 总被引:7,自引:0,他引:7
We present 14 patients with jugular foramen neuromas treated in the professorial unit at the National Hospital, Queen Square, in the 20-year period from 1969 to 1989. The growth characteristics and associated symptomatology of these tumors are variable, and often they do not give rise to a typical jugular foramen syndrome, making differentiation from other low cerebellopontine angle tumors difficult and occasionally impossible. One tumor presented mainly in the neck, but the remaining 13 were predominantly intracranial and their anatomical relationships as defined radiologically determined the surgical approach used. Nine tumors were resected using a posterior fossa approach, three required a combined posterior fossa and neck dissection, and one a combined supratentorial and infratentorial craniotomy. The aim of operation was total excision of the tumor, which was achieved in 10 patients; the remaining three all suffered recurrence. There was no operative mortality and little long-term disability. 相似文献
45.
Awoniyi O. Awonuga Nicola Dean Jamal Zaidi Rudiger U. Pittrof Jinan S. Bekir Seang-Lin Tan 《Journal of assisted reproduction and genetics》1996,13(4):293-297
Aim: Our aim was to compare the outcome in subsequent frozen embryo replacement cycles in four groups of patients who had elective cryopreservation of all their embryos because they were considered to be at increased risk of developing severe ovarian hyperstimulation syndrome.
Design: Sixty-two (91%) of 68 IVF cycles (68 patients) in which elective cryopreservation of all embryos was performed were analyzed. All patients continued on the GnRH agonist, buserelin, after oocyte recovery until the onset of vaginal bleeding. Frozen embryo replacement occurred in a hormone replacement cycle that started either on day 3 of the withdrawal bleed (group I;N=15) or after serum estradiol levels had fallen to <100 pmol/L (group II;N=16). The other patients commenced a frozen embryo replacement cycle several months later in either a hormone replacement (group III;N=15) or a natural (group IV;N=16) cycle.
Results: Two patients developed severe ovarian hyperstimulation syndrome. There were no significant differences among the four groups regarding demographic variables, the dose of hMG used, and the clinical outcome. There was a higher but not significantly different clinical pregnancy rate in group I (26.7%), compared to group II (12.5%), group III (13.3%), and group IV (18.8%).
Conclusions: Several options exist for the timing and protocol used for frozen embryo replacement in patients who had elective cryopreservation for the prevention of ovarian hyperstimulation syndrome, none of which was found to be clearly superior in this observational report.Presented at the 1994 Annual Conference of the American Fertility Society. 相似文献
46.
通过对动物模型实验治疗的病理观察,评价全肺大容量灌洗治疗矽肺的效果,并优选灌洗液。对40只家兔和10只幼猪经SiO2染尘处理后,各随机分为药物组、盐水组和对照组。4~5周后施行全肺大容量灌洗。治疗后3~5个月处死各组动物,进行病理双盲检查。经统计学秩和检验,兔与猪各组肺矽结节纤维化级别分布的差异有非常显著意义(P<0.005)。经卡方检验,各灌洗组的纤维化程度与对照组相比,差异亦有非常显著意义(P<0.01)。灌洗液中药与盐水比,P<0.05;盐水与西药比,P<0.05。兔和猪矽肺各灌洗组的效果明显优于对照组。灌洗液中药优于盐水,盐水又优于西药 相似文献
47.
本文对62例急性高血压脑出血进行了着重于治疗的分析。脑出血病严重威胁患者生命,死亡率高,病残率高。治疗的关键是绝对卧床,避免搬动;积极治疗及控制脑水肿、降低颅内压;头置冰帽以减低脑耗氧量,减轻脑水肿,促进脑细胞功能的恢复;加强护理,预防及治疗并发症是提高患者生存时间及存活率的重要环节;对出血量多、患者一般情况较好者,作者主张手术治疗,清除颅内血肿,可减轻症状,提高存活率及降低病残率。 相似文献
48.
Doug Joshua Max Wolf Jane Matthews Lee Tan William Sheridan Glenn Pilkingtonh Fiona Page 《Leukemia & lymphoma》1994,14(3):303-309
The Australian Leukaemia Study Group myeloma study (MM1) aimed to determine the prognostic significance of clinical and immunophenotypic markers in patients with multiple myeloma. All patients were treated with standard dose melphalan and prednisone. Seventy-four patients were entered and the median survival was 27 months. Serum beta 2-microglobulin (βM) and albumin levels were the only significant clinical factors influencing survival (p = 0.007 and p = 0.008, respectively). Patients with raised levels of CD38+ lymphocytes at presentation had a significantly shorter survival than patients with normal levels (p = 0.01, logrank test, median 19 months vs 33 months). CD38 antigen expression was independent of β2M but patients with raised levels of CD38 had significantly lower levels of albumin than patients with normal levels (p = 0.001) which may explain their poorer survival. Salmon and Durie stage was not associated with antigen expression. No other B-cell antigens (CD10, CD19, CD20, CD21, CD22, CD23, FMC1 or FMC7) or plasma cell antigens tested (PCA-1) were found to be associated with prognosis. Patients who achieved plateau phase had a better prognosis than those who did not (p = 0.04 in a landmark analysis). Patients who achieved plateau phase following an objective response appeared to have a better prognosis than those who were in plateau phase at presentation (p = 0.09 in a landmark analysis). Light chain isotype suppression (LCIS) was not associated with a significant survival advantage and did not correlate with any known prognostic indicator. We conclude that phenotypic analysis of peripheral blood lymphocytes for CD38 antigen at diagnosis may be useful as a prognostic indicator in patients with myeloma. 相似文献
49.
The mould collection of the Centraalbureau voor Schimmelcultures, Baarn, The Netherlands, was screened for isolates originating from warm-blooded animals. The range of species indicates that distribution of clinically relevant, pathogenic or opportunistic strains over the fungal kingdom is non-random. Some opportunistic fungi possess adaptations to life under hostile environmental conditions, enabling them to survive inside the human body. Presence of melanin or carotene seems to be an important virulence factor. Opportunistic fungi which sporulate in submersion are able to disseminate or cause severe local mycoses when the aspecific immune system of the host is impaired. Mycoses caused by a few dimorphic fungi, mostly in their natural ecological niche living in association with vertebrates, are promoted by specific immune deficiencies. 相似文献
50.
本文应用磁性磷酸酶-抗碱性磷酸酶桥联酶标技术(APAAP),对27例原发性肾小球疾病患者外周血T淋巴细胞亚群进行观察。结果表明:本组病例表现为CD细胞升高,CD细胞减少,和CD/CD比值增加。提示原发性肾小球疾病可导致细胞免疫功能改变,T淋巴细胞亚群的变化,是肾组织损害的一个间接证据,可作为临床诊断一个有价值的参考指标。 相似文献