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排序方式: 共有3321条查询结果,搜索用时 15 毫秒
81.
82.
Sho Saito Kayoko Hayakawa Shinya Tsuzuki Masahiro Ishikane Maki Nagashima Kazuhisa Mezaki Yuko Sugiki Taichi Tajima Nobuaki Matsunaga Satoshi Ide Noriko Kinoshita Yoshiki Kusama Yumiko Fujitomo Takato Nakamoto Yuta Toda Mitsuo Kaku Eiichi N. Kodama Norio Ohmagari 《Antimicrobial agents and chemotherapy》2021,65(3)
83.
Takeshi Saraya Michiaki Mikoshiba Harumi Kamiyama Masakazu Yoshizumi Shigeru Tsuchida Hiroyuki Tsukagoshi Taisei Ishioka Miho Terada Eiichi Tanabe Chizuko Tomioka Haruyuki Ishii Hirokazu Kimura Kunihisa Kozawa Tetsuo Shiohara Hajime Takizawa Hajime Goto 《Journal of clinical microbiology》2013,51(6):1979-1982
The present case provides direct evidence of human herpesvirus 6 reactivation in resected lymph node tissue in a patient with drug-induced hypersensitivity syndrome. This case clearly demonstrates that appropriate pathological evaluation of lymphadenopathy for drug-induced hypersensitivity syndrome, which mimics malignant lymphoma in clinical, radiological, and pathological findings, is required. 相似文献
84.
85.
Ken Higashimoto Toshiyuki Maeda Junichiro Okada Yasufumi Ohtsuka Kensaku Sasaki Akiko Hirose Makoto Nomiyama Toshimitsu Takayanagi Ryuji Fukuzawa Hitomi Yatsuki Kayoko Koide Kenichi Nishioka Keiichiro Joh Yoriko Watanabe Koh-ichiro Yoshiura Hidenobu Soejima 《European journal of human genetics : EJHG》2013,21(11):1316-1319
Perlman syndrome is a rare, autosomal recessive overgrowth disorder. Recently, the deletion of exon 9 and other mutations of the DIS3L2 gene have been reported in patients; however, the mechanism behind this deletion is still unknown. We report the homozygous deletion of exon 9 of DIS3L2 in a Japanese patient with Perlman syndrome. We identified the deletion junction, and implicate a non-allelic homologous recombination (NAHR) between two LINE-1 (L1) elements as the causative mechanism. Furthermore, the deletion junctions were different between the paternal and maternal mutant alleles, suggesting the occurrence of two independent NAHR events in the ancestors of each parent. The data suggest that the region around exon 9 might be a hot spot of L1-mediated NAHR. 相似文献
86.
87.
Kakizaki S Takizawa D Yamazaki Y Nakajima Y Ichikawa T Sato K Takagi H Mori M Kasama K 《Journal of gastroenterology》2008,43(1):86-92
Background. The number of patients with morbid obesity is increasing worldwide. However, the prevalence of morbid obesity is still low
in Japan, and therefore few systematic investigations of liver dysfunction in this population have so far been carried out.
This study aimed to investigate the clinical characteristics in severe obese Japanese patients undergoing laparoscopic Roux-en-Y
gastric bypass surgery (LRYGB). Methods. Eighty-four patients with severe obesity, including 61 Japanese and 23 non-Japanese patients, were analyzed. Results. The mean body mass index (BMI) was 43.7 ± 7.8 kg/m2, and there was no difference between Japanese and non-Japanese patients. Nonalcoholic fatty liver disease (NAFLD) was observed
in 45/59 (76.2%) of the Japanese patients. Although there were no differences in the BMI and body weight, serum ALT was higher
in Japanese patients in comparison to non-Japanese patients (P < 0.05). The indices for insulin resistance were significantly higher in the Japanese patients in comparison to non-Japanese
patients (P < 0.01). The liver/spleen computed tomography (CT) ratios were lower in Japanese patients (P < 0.05). The laboratory data and BMI significantly improved at 1 year after LRYGB in both groups. Conclusions. Racial difference may exist difference may exist in NAFLD in patients with severe obesity. When the BMI is similar, liver
dysfunction among Japanese patients with severe obesity tends to be higher than in non-Japanese patients. Japanese patients
with severe obesity must therefore reduce their body weight to a greater degree in comparison to non-Japanese patients with
the same BMI. LRYGB can achieve effective weight control and lower ALT levels in Japanese patients with severe obesity. 相似文献
88.
Marie-Luise Berres Karen Phaik Har Lim Tricia Peters Jeremy Price Hitoshi Takizawa Hélène Salmon Juliana Idoyaga Albert Ruzo Philip J. Lupo M. John Hicks Albert Shih Stephen J. Simko Harshal Abhyankar Rikhia Chakraborty Marylene Leboeuf Monique Beltr?o Sérgio A. Lira Kenneth M. Heym Bj?rn E. Clausen Venetia Bigley Matthew Collin Markus G. Manz Kenneth McClain Miriam Merad Carl E. Allen 《The Journal of experimental medicine》2015,212(2):281
89.