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31.
Bernard Escudier Padmanee Sharma David F. McDermott Saby George Hans J. Hammers Sandhya Srinivas Scott S. Tykodi Jeffrey A. Sosman Giuseppe Procopio Elizabeth R. Plimack Daniel Castellano Howard Gurney Frede Donskov Katriina Peltola John Wagstaff Thomas C. Gauler Takeshi Ueda Huanyu Zhao Robert J. Motzer 《European urology》2018,73(4):e116-e118
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Tetsuro Tominaga Takashi Nonaka Hiroaki Takeshita Masaki Kunizaki Yorihisa Sumida Shigekazu Hidaka Terumitsu Sawai Takeshi Nagayasu 《The Indian journal of surgery》2018,80(1):54-60
High-age patients have higher rates of comorbidity that are associated with a poor prognosis. It is important to correctly evaluate their preoperative status to avoid mortality. The aim of this study was to clarify whether the Charlson comorbidity index (CCI) was useful for predicting postoperative outcomes. This retrospective study collected data from 250 consecutive patients over 75 years of age. The CCI takes into account 19 comorbid conditions. Inflammation-based scores, including the Glasgow prognostic score (GPS) and the platelet to lymphocyte ratio (PLR), are other preoperative scoring systems. The relationships among these scores and postoperative outcomes were evaluated. The patients were classified according to their vital status (dead, n = 30 or alive, n = 220). Comorbidities, the presence of double cancer, and lymph node metastases were significantly different between the groups (p < 0.01, p = 0.01, and p < 0.01). In regard to the scoring systems, the CCI, GPS, and PLR were significantly different (p = 0.02, p = 0.03, and p = 0.05). Multivariate analysis identified CCI ≥ 2 (hazard ratio (HR) = 5.24, 95 % confidence interval (CI) = 1.30–12.1, p = 0.01) as a significant determinant of postoperative outcome (p < 0.01). The overall survival tended to be lower in patients with high CCI scores group (p = 0.03). The CCI was useful to predict postoperative outcomes in high-age colorectal cancer patients. 相似文献
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Journal of Natural Medicines - Investigations of antibacterial activities revealed that the incorporation of longer alkyl chains to the C-6 position in resorcylic acid conferred antibacterial... 相似文献
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Takeshi Takahara Go Wakabayashi Hiroyuki Nitta Yasushi Hasegawa Hirokatsu Katagiri Daiki Takeda Kenji Makabe Akira Sasaki 《肝胆外科与营养》2015,4(6):398-405
Background
In a statement by the second International Consensus Conference for Laparoscopic Liver Resection (LLR), minor LLR was confirmed to be a standard surgical practice, as it has become adopted by an increasing proportion of surgeons. However, it is unclear whether this applies to the more complex group of patients suffering from cirrhosis. Therefore, the aim of this retrospective study was to compare the feasibility and safety of LLR for hepatocellular carcinoma (HCC) between non-liver cirrhosis (NLC) patients and liver cirrhosis (LC) patients at a single high-volume laparoscopy center.Methods
From the beginning of 2000 to the end of 2013, open liver resection (OLR) was performed in 99 HCC patients, and LLR was in 118. The HCC patients who underwent LLR were divided into NLC-LLR (n=60) and LC-LLR (n=58) groups, and we compare the short-term outcomes between them.Results
There was no significant difference in the incidence of blood loss and transfusion requirements between the NLC-LLR group and the LC-LLR group, although wedge resection was mainly performed in the LC-LLR group. There was no significant difference in the complication rate between the two groups, and the remarkable finding was that there was a significantly lower incidence of postoperative ascites in the LC-LLR group than in the NLC-LLR group.Conclusions
According to our experience, it appears that LLR for selected HCC patients with cirrhosis is a feasible and promising procedure that is associated with less blood loss and fewer postoperative complications, especially the incidence of postoperative ascites. Further investigations are clearly warranted. 相似文献38.
Terazawa Takeshi Nishimura Takanori Mitani Tomohiro Ichii Osamu Ikeda Teppei Kosenda Keigo Tatsumi Eisuke Nakayama Yasuhide 《Journal of artificial organs》2018,21(3):387-391
Journal of Artificial Organs - A type-C mold based on in-body tissue architecture was previously developed for preparing small-diameter biotube vascular grafts with a 2-mm diameter and... 相似文献
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Ichiro Sekiya Takeshi Muneta Masafumi Horie Hideyuki Koga 《Clinical orthopaedics and related research》2015,473(7):2316-2326