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31.
Masuda H Ozawa M Kurita S Saito Y Ichinose Y 《Hinyokika kiyo. Acta urologica Japonica》2000,46(12):923-925
We investigated the clinical statistics of the operations and inpatients since the establishment of the department in June 1994 up to May 1999. The total number of inpatients was 1,269 (1,047 males and 222 females), and a total of 1,098 operations were performed. Extracorporeal shock wave lithotriopy (ESWL) was also introduced in 1997, and in addition, it seemed that the number of operations and inpatients would be increasing in future. 相似文献
32.
We investigated the correlation between clinical severity and striatal [123I]-CIT binding in 12 patients with Parkinson's Disease (PD: 6 men and 6 women, age: 65 +/- 7 years, Hoehn & Yahr stage: 1 to 3). The clinical severity of PD patients was measured with the Unified Parkinson's Disease Rating Scale (UPDRS) after withdrawal of antiparkinsonian medication at least 12 hours before assessment. [123I]beta-CIT binding in the caudate and putamen was measured at 3 hours [V'3 (day 1)], and at 24 hours [V'3 (day 2)) after tracer injection with small square ROIs. The specific striatal uptake index (day 2) was calculated with large square ROIs that encompassed the whole striatum. The best correlation (r = -0.82, p < 0.0012) was between putamenal V'3 (day 2) and the motor UPDRS scores. When the motor UPDRS scores were divided into four subscales, bradykinesia was the only sign that correlated significantly with putamenal V'3 (day 2) (r = -0.81, p < 0.002). [123I]beta-CIT SPECT is a useful marker of disease severity in PD with potential utility in the serial monitoring of disease progression. 相似文献
33.
Endoscopic features associated with development of metachronous gastric cancer in patients who underwent endoscopic resection followed by Helicobacter pylori eradication 下载免费PDF全文
34.
Ryoichi Saito Shiho Matsuoka Yuji Fujinami Shotaro Nonaka Shizuko Ichinose Tetsuo Kubota Noboru Okamura 《Research in microbiology》2013,164(3):236-243
Moraxella catarrhalis, an important pathogen in the human respiratory tract, causes otitis media and lower respiratory tract infections. M. catarrhalis outer membrane protein CD (OMPCD) is a major heat-modifiable OMP with demonstrable potential as a vaccine candidate. The gene encoding OMPCD of M. catarrhalis strains was subjected to nucleotide sequence analysis and then inactivated by insertional mutagenesis. The ompCD mutant strains exhibited a modest growth defect in comparison with the wild-type strains. In optical microscopy and scanning/transmission electron microscopy examinations, regarding morphology, the cell size and cell wall of the ompCD mutant strains were significantly larger and thinner, respectively, than those of the wild-type strain. Furthermore, the ompCD mutant strains exhibited significant autoaggregation and increased surface hydrophobicity, in addition to a reduction in the adherence to HEp-2 cells, compared to the wild-type strains. Strains repaired by replacing the mutated ompCD gene exhibited phenotypic characteristics very similar to those of the wild-type strains. These results indicate that M. catarrhalis OMPCD, in addition to its functions related to bacterial growth and adherence to human epithelial cells, plays a very important role in bacterial physiology and pathogenesis, including aspects such as stabilizing bacterial cell morphology and preventing autoaggregation by reducing surface hydrophobicity. 相似文献
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Takamichi Ito Yuichi Yoshida Koji Adachi Masutaka Furue Osamu Yamamoto 《Yonago acta medica》2012,55(4):81-82
Depigmented haloes sometimes appear around melanocytic tumors or non-melanocytic
tumors, but coexistence of warts and depigmented haloes is extremely rare. We report
here an unusual case of warts accompanied by depigmented haloes and
subsequently-triggered generalized vitiligo. A 55-year-old Japanese man presented
with a 3-year history of brown nodules on the back, upper eyelid and dorsum of
the left hand. Depigmented haloes appeared around the noldules and then gradually spread
over a wide area, resulting in the development of generalized vitiligo. He had no history
of antecedent treatment for these lesions before consultation. Histopathologically,
the lesion showed papillomatosis and hyperkeratosis with lymphocytic exocytosis
into the epidermis, which compatible to warts. Based on these clinical and
histopathologic findings, a diagnosis of warts with depigmented halo and
subsequently-triggered generalized vitiligo was made. None of the warts had resolved
spontaneously after the appearance of haloes, and the depigmented haloes and generalized
vitiligo remain unchanged. 相似文献
40.
Yasuyuki Shiraishi Shun Kohsaka Takayuki Abe Kazumasa Harada Tetsuro Miyazaki Takamichi Miyamoto Kiyoshi Iida Shuzou Tanimoto Mayuko Yagawa Makoto Takei Yuji Nagatomo Toru Hosoda Takeshi Yamamoto Ken Nagao Morimasa Takayama 《The American journal of medicine》2018,131(2):156-164.e2