全文获取类型
收费全文 | 28625篇 |
免费 | 1339篇 |
国内免费 | 159篇 |
专业分类
耳鼻咽喉 | 275篇 |
儿科学 | 507篇 |
妇产科学 | 479篇 |
基础医学 | 3762篇 |
口腔科学 | 567篇 |
临床医学 | 1778篇 |
内科学 | 7137篇 |
皮肤病学 | 506篇 |
神经病学 | 2339篇 |
特种医学 | 1141篇 |
外科学 | 4715篇 |
综合类 | 118篇 |
一般理论 | 5篇 |
预防医学 | 817篇 |
眼科学 | 577篇 |
药学 | 1792篇 |
中国医学 | 41篇 |
肿瘤学 | 3567篇 |
出版年
2023年 | 206篇 |
2022年 | 429篇 |
2021年 | 703篇 |
2020年 | 380篇 |
2019年 | 527篇 |
2018年 | 636篇 |
2017年 | 506篇 |
2016年 | 548篇 |
2015年 | 573篇 |
2014年 | 743篇 |
2013年 | 896篇 |
2012年 | 1503篇 |
2011年 | 1475篇 |
2010年 | 828篇 |
2009年 | 729篇 |
2008年 | 1222篇 |
2007年 | 1431篇 |
2006年 | 1336篇 |
2005年 | 1316篇 |
2004年 | 1271篇 |
2003年 | 1226篇 |
2002年 | 1279篇 |
2001年 | 726篇 |
2000年 | 785篇 |
1999年 | 749篇 |
1998年 | 337篇 |
1997年 | 270篇 |
1996年 | 264篇 |
1995年 | 235篇 |
1994年 | 231篇 |
1993年 | 213篇 |
1992年 | 658篇 |
1991年 | 576篇 |
1990年 | 562篇 |
1989年 | 570篇 |
1988年 | 514篇 |
1987年 | 492篇 |
1986年 | 437篇 |
1985年 | 445篇 |
1984年 | 252篇 |
1983年 | 214篇 |
1982年 | 108篇 |
1979年 | 230篇 |
1978年 | 128篇 |
1977年 | 105篇 |
1975年 | 98篇 |
1974年 | 98篇 |
1973年 | 97篇 |
1970年 | 100篇 |
1969年 | 115篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
Kengo Maeda Shinji Kume Yoshihiko Nishio Shiro Maeda Yasuhiro Nishida Mikio Suzuki Takahiro Nakaguchi Toru Kawabata Osamu Hashimoto Takashi Hisanaga Atsunori Kashiwagi Hitoshi Yasuda 《Clinical neurology》2006,46(4):266-269
We report a 53-year-old woman with severe Graves' ophthalmopathy accompanied by uncontrolled myasthenia gravis. She presented remarkable exophthalmos, chemosis, and restriction of eye movement. Despite plasma exchange, steroid pulse therapy, local injection of steroid, and irradiation, ocular symptoms did not ameliorate. Since optic neuropathy was seen, orbital decompression surgery was performed in the left eye. Bilateral chemosis was improved after the surgery. Five years after surgery, there was no ocular palsy in the operated left eye, but in the contralateral eye. For the good prognosis of the eye movement, orbital decompression might be recommended in the severe Graves' ophthalmopathy accompanied by the optic neuropathy and/or ophthalmoplegia with proptosis. 相似文献
12.
Takako Miyamae Masaaki Mori Yasuji Inamo Youichi Kohno Shuji Takei Motoharu Maeda Takuji Murata Shuji Nakata Hiroshi Kawai Yukiko Hirano Yukiji Date Katsuhiko Kitamura Shumpei Yokota 《Ryūmachi》2003,43(3):538-543
OBJECTIVES: To reveal the frequency and the clinical characteristics of dystrophic calcification that occurs in children with juvenile dermatomyositis, multi-center analysis was constructed. METHOD: Fifty children with JDM were enrolled, and 14 of them (28.0%) were complicated with calcinosis. Clinical symptoms and laboratory tests at onset, initial therapy and disease course were compared in children with and without calcinosis. RESULTS: The mean age of the onset of calcinosis was 4.78 +/- 3.33 years, and it was younger than those of children without calcinosis (8.66 +/- 3.85 years) (P = 0.0017). No differences of clinical manifestation except Gower's sign were observed. The frequency of positive anti-nuclear antibody was 7.1% in children with calcinosis and 52.9% without calcinosis (P = 0.0112). The initial therapy of methylprednisolon pulses gave no effects on prognosis of calcium deposition. The calcinosis appeared in 1.56 +/- 1.91 year after the onset of the disease. The various types of calcium deposition including large tumorous clumps, subcutaneous plaques or nodules, sheet-type calcification were deserved. They appeared over knee joints (64.3%), elbow joint (64.3%), and hip processes (50.0%). Calcinosis affecting the subcutaneous tissues frequently resulted in painful superficial ulceration of the overlying skin (42.9%), local infection (50.0%), and limitation of joint movement (14.3%). Although aluminum phosphate was effective in 2 children among 7, no other effective treatment was recommended. In 5 cases, surgical removal of tumorous clumps was operated. Thus, juvenile dermatomyositis is frequently complicated with calcinosis. This type of calcinosis was found to be unlikely to resolve completely, and resulted in severe disability in children. 相似文献
13.
Journal of Digital Imaging - 相似文献
14.
15.
M Kitamura T Nishihira K Hirayama S Kawachi T Kano T Akaishi R Shineha Y Sekine K Sanekata S Mori 《[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai》1989,37(1):17-24
From 1976 to 1985, 277 cases of carcinoma of the esophagus were resected in the Second Department of Surgery, Tohoku University School of Medicine. Postoperative cardiocirculatory disturbances occurred in 114 cases (41.2%), arrhythmia being the disturbance most frequently observed (86.8%). Low cardiac output syndrome occurred in 8 cases and myocardial infarction occurred in 3 cases. The majority of the cases were treated successfully, but 5 patients died within one month after operation. Causes of death were as follows: myocardial infarction, constrictive pericarditis, cardiac tamponade, non-occlusive mesenteric ischemia and acute cardiac failure. Postoperative arrhythmia occurred mainly up to the third postoperative day. Low cardiac output syndrome occurred just after operation or on the first postoperative day. All cases of myocardial infarction occurred on the first postoperative day. The rate of occurrence of cardiocirculatory disturbances in aged patients (greater than or equal to 70) was significantly higher than other group (less than or equal to 69), (56.7%:38.1%, p less than 0.05). The rate of occurrence of cardiocirculatory disturbances in patients who had a history of hypertension or in patients with abnormal preoperative electrocardiographic findings were relatively higher than those in patients who had no history of hypertension or in patients with no abnormal preoperative electrocardiographic findings. The rate of occurrence of cardiocirculatory disturbances in patients who had undergone total resection of the thoracic esophagus was significantly higher than that in patients who had undergone partial resection of the thoracic esophagus (42.8%:23.8%, p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
16.
17.
Yoshiei Shimamura Takahiro Takemura Kouta Agematsu Takuma Yamazaki 《Annals of thoracic and cardiovascular surgery》2005,11(5):350-351
This article describes the construction and use of a new end graft holder during coronary artery bypass grafting (CABG). The instrument consists of a pinching device attached to a flexible arm and a fixation clamp. This device provides secure stabilization and enables excellent positioning of the graft without producing graft injury. 相似文献
18.
19.
N Mori 《Nihon Shokakibyo Gakkai zasshi》1987,84(5):1057-1067
20.
Effect of the free radical scavenger MCI-186 on spinal cord reperfusion after transient ischemia in the rabbit 总被引:4,自引:0,他引:4
Kenichi Hashizume Toshihiko Ueda Hideyuki Shimizu Atsuo Mori Ryohei Yozu 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2005,53(8):426-433
Objective: Paraplegia remains a serious complication of aortic operations. The production of free radicals during reperfusion
after transient ischemia is believed to induce secondary spinal neuronal injury, resulting in paraplegia. The aim of the present
study was to clarify the protective effect and method of administration of antioxidants on the neurological and histological
outcome in the animal model for reperfusion injury after transient spinal cord ischemia. Methods: New Zealand white rabbits underwent surgical exposure of the abdominal aorta that was clamped for 15 minutes to achieve spinal
cord ischemia. Group A animals received two 10 mg/kg doses of 3-methyl-l-phenyl-2-pyrazolin-5-one (MCI-186) at the time of
release of the aortic clamp and 30 minutes later. In group B, MCI-186, 5 mg/kg, was given three times, at the time of aorta
clamp release, 30 minutes and 12 hours later. In group C (control group), one dose of vehicle was administered. Neurological
status was assessed using modified Tarlov’s score until 168 hours after operation. Spinal cord sections were examined microscopically
to determine the extent of ischemic neuronal damage. Results: Groups A and B animals had better neurological function than group C (p(0.001). In contrast, group C animals exhibited paraplegia or paraparesis with marked neuronal necrosis. The number of surviving
neurons within examined sections of the spinal cord was significantly greater in group B than in group C (p(0.001). Conclusion: In a 15-minute ischemia-reperfusion model using rabbits, systemic repetitious administration of MCI-186, a free radical scavenger,
was found to have a protective effect on the spinal cord neurons both neurologically and histologically. We postulate that
the drug minimizes the delayed neuronal cell death for reperfusion injury after transient ischemia by reducing the free radical
molecules. Moreover, it was thought that we could protect delayed neuronal cell death more effectively by administering MCI-18612
hours later. 相似文献