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941.
D Mabin J P Borsotti S Tea J C Le Mevel J Clavier 《Revue d'électroencéphalographie et de neurophysiologie clinique》1986,15(4):341-348
Eleven patients with bronchial epidermoid carcinoma and undergoing treatment with cis-D.D.P. (II) were kept under electrophysiological and clinical surveillance. No other neurotoxic medication was added. The total dose of cis-D.D.P. was 300 mg/m2 over a period of three months: namely, three courses of 100 mg/m2 distributed over 5 days. Following the pretreatment check-up, the patients were divided into two groups: those without any electrophysiological abnormality (group A), and those without clinical abnormality but with a delayed latency H of the Hoffmann Reflex (group B). Patients in group A showed a slowing down of the motor nerve conduction velocity of the Median and Peroneal Nerves after a course of 100 mg, without accompanying worsening of the conduction velocity after 300 mg/m2, and prolongation of the distal latency of the sensory Median Nerve after 300 mg/m2; in group B, no significant change of electrophysiological clinical features were noted. In the two groups a non-significant reduction in amplitude of evoked responses were noted. These findings are more consistent with an axonal injury than with functional myelin injury. The authors review the existing literature and discuss the physiopathologic mechanisms of cis-D.D.P. peripheral neuropathies. 相似文献
942.
Cocaine-treated rats acquired a preference for cocaine-associated contextual stimuli (CS) relative to saline-injected control rats. However, when animals were given repeated tests for conditioned place preference intermittent between conditioning trials, they displayed an attenuation in strength of conditioning. This attenuation was not due to pharmacologic tolerance (Experiment 1), but rather reflected a disruption in learning due to exposure to the CS alone (Experiment 2). Like other examples of classical conditioning, the strength of the conditioned response (CR) as assessed by the conditioned place preference model may be influenced by partial reinforcement. 相似文献
943.
Forty patients suffering from asthmatic conditions, often accompanied by emphysema, were treated either with an extempore combination of salbutamol syrup plus 30-mg oxatomide tablets or with 30-mg oxatomide tablets alone for purposes of comparison. Greater efficacy was obtained with the combination, which produced positive results in terms of improved respiratory status, remission of clinical symptoms and reduced anti-asthma drug requirements in 90% of the cases treated, as against only 55% of satisfactory results obtained with oxatomide alone. The combination was very well tolerated with no incidence of adverse reactions, while the treatment with oxatomide alone, though on the whole well tolerated, gave rise to mild drowsiness in four cases. 相似文献
944.
945.
The Brief Symptom Inventory (BSI), a 53-item psychiatric symptom checklist, was administered to 57 alcoholic inpatients on days 2, 10, 18 and 26 of their 28-day stay in an alcoholism rehabilitation unit at a Veterans Administration hospital. The results of the test show a steady decline in the patients' psychiatric symptomatology from week 1 to week 4 with the most dramatic improvement evidenced between weeks 1 and 2. 相似文献
946.
R W Wulkan L Zwang T L Liem B G Blijenberg B Leijnse 《Zeitschrift für klinische Chemie und klinische Biochemie》1987,25(10):719-722
An expert system for evaluation of X-ray diffraction patterns of urinary calculi is described and evaluated. The software was developed using the PERSONAL CONSULTANT expert system shell from Texas Instruments. 相似文献
947.
948.
The authors have presented the results of a 14-day open randomized trial of the efficacy of 3 calcium inlet blocking agents: nifedipine, verapamil and phendilin in 61 patients with Raynaud's syndrome. In the group of patients receiving 30-80 mg of nifedipine (20) there was a significant decrease in the frequency and expression of Raynaud's syndrome attacks, a positive effect of varying degree was noted in 19 patients. The drug raised slightly the skin and muscular blood flow and skin temperature. The use of 120-360 mg of verapamil in 21 patients caused no significant inhibition of Raynaud's syndrome and rise of hemocirculation. Phendilin (150-300 mg) though being comparable with nifedipine in efficacy, often produced side-effects resulting in the drug cancellation (8 out of 20). The efficacy of the calcium inlet blocking agents, especially nifedipine, for therapy of Raynaud's syndrome was emphasized. 相似文献
949.
T Lohner 《Primary care》1987,14(1):13-23
This discussion has dealt with the nature of adolescence in the context of our culture. The stages of early adolescence (10 to 13 years), middle adolescence (14 to 17 years), and late adolescence (over 17 years) were examined separately and in some detail. Other characteristics of adolescence in general were examined, as were some of the factors influencing adult-adolescent interactions as well as the relationship between the adolescent and the society. Lastly, some of the ways in which this knowledge can be useful clinically were discussed, along with approaches to working successfully with teenagers and making their care a most enjoyable and rewarding part of clinical practice. 相似文献
950.