全文获取类型
收费全文 | 12218篇 |
免费 | 690篇 |
国内免费 | 31篇 |
专业分类
耳鼻咽喉 | 124篇 |
儿科学 | 627篇 |
妇产科学 | 242篇 |
基础医学 | 1768篇 |
口腔科学 | 128篇 |
临床医学 | 917篇 |
内科学 | 2585篇 |
皮肤病学 | 263篇 |
神经病学 | 640篇 |
特种医学 | 349篇 |
外国民族医学 | 1篇 |
外科学 | 1263篇 |
综合类 | 468篇 |
一般理论 | 8篇 |
预防医学 | 824篇 |
眼科学 | 521篇 |
药学 | 1074篇 |
中国医学 | 92篇 |
肿瘤学 | 1045篇 |
出版年
2023年 | 85篇 |
2022年 | 234篇 |
2021年 | 403篇 |
2020年 | 178篇 |
2019年 | 242篇 |
2018年 | 315篇 |
2017年 | 223篇 |
2016年 | 283篇 |
2015年 | 319篇 |
2014年 | 416篇 |
2013年 | 542篇 |
2012年 | 739篇 |
2011年 | 796篇 |
2010年 | 443篇 |
2009年 | 385篇 |
2008年 | 601篇 |
2007年 | 680篇 |
2006年 | 607篇 |
2005年 | 536篇 |
2004年 | 471篇 |
2003年 | 423篇 |
2002年 | 407篇 |
2001年 | 312篇 |
2000年 | 293篇 |
1999年 | 231篇 |
1998年 | 101篇 |
1997年 | 80篇 |
1996年 | 72篇 |
1995年 | 61篇 |
1994年 | 54篇 |
1993年 | 53篇 |
1992年 | 160篇 |
1991年 | 149篇 |
1990年 | 130篇 |
1989年 | 132篇 |
1988年 | 157篇 |
1987年 | 122篇 |
1986年 | 125篇 |
1985年 | 122篇 |
1984年 | 104篇 |
1983年 | 67篇 |
1982年 | 56篇 |
1979年 | 73篇 |
1978年 | 68篇 |
1977年 | 54篇 |
1976年 | 55篇 |
1974年 | 60篇 |
1973年 | 68篇 |
1971年 | 59篇 |
1970年 | 58篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
P K Mediratta N Das V S Gupta P Sen 《The Journal of allergy and clinical immunology》1988,81(1):27-32
The effects of opioid agonists and antagonists were investigated on humoral immune mechanisms in mice and rats. Opioid agonists like morphine, Leu-enkephalin, and Met-enkephalin, enhanced antigen-induced histamine release from mixed peritoneal cells of rats in vitro; this enhancement was effectively antagonized by naloxone, an opioid antagonist. Naloxone, per se, decreased anaphylactic mortality in doses of 10 mg/kg, while it increased mortality in a dose of 1 mg/kg. Reduced IgE antibody titer, measured by passive cutaneous anaphylaxis, decreased hemagglutination titer to sheep red blood cells, blocked histamine release from mixed peritoneal cells of rats in vitro induced by antigen, but had no significant effect when histamine release was induced by compound 48/80. Thus, it appears that endogenous opioids are involved in humoral immune responses. 相似文献
102.
Shahid M Dhillion VS Jain N Hedau S Diwakar S Sachdeva P Batra S Das BC Husain SA 《Molecular human reproduction》2004,10(7):521-526
103.
Serotypic and genotypic characterization of human serotype 10 rotaviruses from asymptomatic neonates. 总被引:2,自引:7,他引:2
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
S J Dunn H B Greenberg R L Ward O Nakagomi J W Burns P T Vo K A Pax M Das K Gowda C D Rao 《Journal of clinical microbiology》1993,31(1):165-169
Human rotaviruses were isolated from asymptomatic neonates at various hospitals and clinics in the city of Bangalore, India, and were found to be subgroup I specific and possess long RNA patterns (M. Sukumaran, K. Gowda, P. P. Maiya, T. P. Srinivas, M. S. Kumar, S. Aijaz, R. R. Reddy, L. Padilla, H. B. Greenberg, and C. D. Rao, Arch. Virol. 126:239-251, 1992). Three of these strains were adapted to tissue culture and found by serotype analysis and neutralization assays to be of serotype 10, a serotype commonly found in cattle but infrequently found in humans and not previously identified in neonates. By RNA-RNA hybridization, a high level of relatedness to a serotype 10 bovine rotavirus strain and a low-to-medium level of relatedness to a human rotavirus strain were observed. Since this human isolate shares a genogroup with bovine rotavirus, it is likely that it originated by interspecies transmission. A human rotavirus strain isolated from asymptomatic neonates and similar to bovine rotavirus might represent a good vaccine candidate. 相似文献
104.
The National Football Head and Neck Injury Registry. 14-year report on cervical quadriplegia, 1971 through 1984 总被引:2,自引:0,他引:2
Data on cervical spine injuries resulting from participation in football have been compiled by a national registry. Analysis of epidemiologic data and cinematographic documentation clearly demonstrated that the majority of cervical fractures and dislocations were due to axial loading. On the basis of this observation, rule changes banning both deliberate "spearing" and the use of the top of the helmet as the initial point of contact in making a tackle were implemented at the high school and college level. Subsequently, a marked decrease in cervical spine injury rates has occurred. The occurrence of permanent cervical quadriplegia decreased from 34 in 1976 to five in the 1984 season. It is suggested that axial loading of the cervical spine is also responsible for the catastrophic injuries in diving, rugby, ice hockey, and gymnastics. Implementation of appropriate changes in playing techniques and/or equipment modifications could possibly reduce the incidence of cervical spine injuries in these activities. 相似文献
105.
Mark A. Rabinovitch Victor Kalff Richard Allen Amnon Rosenthal James Albers Sunil K. Das Bertram Pitt Dennis P. Swanson Thomas Mangner W. Leslie Rogers James H. Thral William H. Beierwaltes 《European journal of nuclear medicine and molecular imaging》1985,10(5-6):222-227
The utility of -123I-hexadecanoic acid myocardial scintigraphy as a metabolic probe of cardiomyopathies was investigated. Sixteen patients with a variety of cardiomyopathies and myopathies that involve cardiac muscle and ten volunteers were imaged in the postabsorptive state in a 40° LAO projection after a standard dose of -123I-hexadecanoic acid. An elimination T1/2 was calculated from the left ventricular myocardial time-activity curve. An uptake index, corrected for chest wall attenuation, was also computed in 7 of 10 volunteers and 8 of 16 patients.Of the 16 patients, only 2 had distinctly abnormal -123I-hexadecanoic acid myocardial tracer kinetics. The first patient had a metabolic disorder of which cartine deficiency was one component. The second patient had endocardial fibroelastosis, a process which has been linked to disorders which deprive the myocardium of oxygen and energy. Therefore, the cardiomyopathy may have been caused by some abnormality of cardiac metabolism other than carnitine deficiency. Although of limited utility in the overall cardiomyopathic population, -123I-hexadecanoic acid myocardial scintigraphy should be further investigated as a screening test for carnitine deficiency and related metabolic abnormalities in patients at risk.Supported by a Canadian Heart Foundation Research FellowshipSupported by an Australian Heart Foundation Travel Grant 相似文献
106.
Ghosal Shibnath Shanthy Amirthalingam Mukhopadhyay Mita Sarkar Mihir K. Das Prasun K. 《Pharmaceutical research》1986,3(4):240-243
The effect of lycoriside, an acylglucosyloxy alkaloid from Crinum asiaticum Linn, (family Amaryllidaceae), with or without sitosterol-3-O--D-glucoside, was studied on the rate of degranulation of peritoneal mast cells of albino rats. Lycoriside, at lower concentrations (1–20 µg/ml), in vitro, produced statistically significant protection against Tween 80-induced degranulation, as also to sensitized mast cells challenged with an antigen (horse serum). It also provided protection against compound 48/80-induced degranulation of mast cells when administered in vivo (1–5 mg/kg, po). At higher concentrations (100 µg/ml and above), in vitro, however, it had a mast-cell degranulation effect per se. The addition of sitosterol-3-O--D-glucoside to lycoriside did not modify the effect of the latter compound. The mechanism of the dual response elicited by lycoriside is appraised in view of a concentration-dependent anti- or prerelease effect on mast-cell mediators. 相似文献
107.
Hasan M. Tasdik Hossain Sahadat Gupta Rajat Das Podder Vivek Mowri Naima Afroz Ghosh Anindita Mahmood Hassan Rushekh Ahmmed Faisal Khatun M. S. T. Halima Nodi Rhedeya Nury Koly Kamrun Nahar Yasmeen Sharmeen Islam Nazrul 《Zeitschrift fur Gesundheitswissenschaften》2022,30(2):465-473
Journal of Public Health - Depression is a major morbidity and the most common mental disorder among the medical students in medical schools globally. Undergraduate students suffer stress more due... 相似文献
108.
Undurti N. Das 《Canadian Medical Association journal》2001,165(7):908-909
109.
M. Karthik Selvaraj Tapan Kumar Das Nikhil Joseph Martin M. Shyam Sundar David V. Rajan 《Indian Journal of Orthopaedics》2021,55(3):723
IntroductionLatarjet procedure is commonly performed for recurrent anterior shoulder instability with glenoid side bone loss. Classic Latarjet procedure can be performed using specially designed drill guides, jigs, or by freehand technique. Here we have described a technical note on classic Latarjet procedure performed with freehand technique utilizing simple rulers and caliper. The functional and radiological outcomes of our patients have also been analysed.Material and Methods149 open classic Latarjet procedures were performed using our technique between March 2015 and July 2018. The mean age of the patients was 32.95 years (Range 22–59 years). The functional outcome of the patients was measured using Western Ontario Shoulder Instability (WOSI) and Oxford Shoulder Instability Score (OSIS) at 2 years of follow-up. Screw and graft positioning were studied in 24 consecutive patients with a postoperative computed tomography (CT) scan.ResultsThere was no incidence of recurrent subluxation or dislocation post-surgery. Mean OSIS score increased from 15.63 ± 3.20 preoperatively to 42.44 ± 3.88 postoperatively (p value < 0.05). WOSI score decreased significantly from 62.54% ± 8.24 to 10.26 ± 6.33 postoperatively at 2-year follow-up (p value < 0.05). Postoperative CT scan also showed satisfactory screw placement in all patients.ConclusionOpen Latarjet procedure performed using freehand technique provides good functional and radiological outcomes in patients with recurrent anterior shoulder instability with glenoid side bone loss.Supplementary InformationThe online version contains supplementary material available at 10.1007/s43465-021-00385-7. 相似文献
110.
Caroline C. Eskind Meghan H. Shilts Ciara M. Shaver Suman R. Das Gowri Satyanarayana 《American journal of transplantation》2021,21(7):2333-2340
With the introduction of high-throughput sequencing methods, our understanding of the human lower respiratory tract's inhabitants has expanded significantly in recent years. What is now termed the “lung microbiome” has been described for healthy patients, as well as people with chronic lung diseases and lung transplants. The lung microbiome of lung transplant recipients (LTRs) has proven to be unique compared with nontransplant patients, with characteristic findings associated with disease states, such as pneumonia, acute rejection, and graft failure. In this review, we summarize the current understanding of the lung microbiome in LTRs, not only focusing on bacteria but also highlighting key findings of the viral and the fungal community. Based on our knowledge of the lung microbiome in LTRs, we propose multiple opportunities for clinical use of the microbiome to improve outcomes in this population. 相似文献