Lack of an association between coffee consumption and lipoprotein lipids and apolipoproteins in young adults: The beaver county study

The relationship between coffee consumption and lipoprotein lipids and apolipoproteins was examined in 472 white men and women (20-24 years of age) in Beaver County, Pennsylvania, during 1981-1982. Coffee intake, expressed as nondrinker, one to two cups per day, and three or more cups per day, was unrelated to total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, or apoproteins AI, AII, or B. After covariate adjustment for cigarette smoking, alcohol intake, body mass index, and adherence to a diet low in cholesterol and saturated fat, the results remained essentially unchanged. The only statistically significant finding was that women who consumed three or more cups of coffee per day had significantly lower triglyceride concentrations compared with coffee nondrinkers (P less than 0.05). Thus, these findings fail to substantiate a significant association of low to moderate coffee intake with an increased lipid and apoprotein risk profile in these young adults.     

Health Services Use Among Jailed Women with Alcohol Use Disorders

Correctional facilities now house unprecedented numbers of women with complex treatment needs. This investigation applied the Behavioral Model for Vulnerable Populations to study 168 jailed women with alcohol use disorders. It described the sample’s predisposing (age, race, victimization), enabling (health insurance), and need (self-reported medical, substance use, and mental health problems) factors and examined associations of these factors with pre-incarceration services utilization. Most participants had clinically significant levels of depression and PTSD symptoms, most took psychiatric medications, and most had been victimized. Participants reported considerable health services utilization. Younger, Black, and uninsured women utilized fewer medical and mental health services. Drug use was associated with less use of medical services, but more use of alcohol and drug services. High rates of health services use support the need for integrated, ongoing care for substance-using women before, during, and after incarceration.

     

Methodology of a nationwide cross-sectional survey of prevalence and epidemiological patterns of hepatitis A, B and C infection in Brazil

A population-based survey to provide information on the prevalence of hepatitis viral infection and the pattern of risk factors was carried out in the urban population of all Brazilian state capitals and the Federal District, between 2005 and 2009. This paper describes the design and methodology of the study which involved a population aged 5 to 19 for hepatitis A and 10 to 69 for hepatitis B and C. Interviews and blood samples were obtained through household visits. The sample was selected using stratified multi-stage cluster sampling and was drawn with equal probability from each domain of study (region and age-group). Nationwide, 19,280 households and ~31,000 residents were selected. The study is large enough to detect prevalence of viral infection around 0.1% and risk factor assessments within each region. The methodology seems to be a viable way of differentiating between distinct epidemiological patterns of hepatitis A, B and C. These data will be of value for the evaluation of vaccination policies and for the design of control program strategies.     

Poverty, health services, and health status in rural America

Access to health services for everyone has been a major policy goal in the United States: inequitable access is assumed to lead to inequitable health status, particularly for low-income groups. A sophisticated model of the relation between poverty, health care needs, service use, and health outcomes is used to analyze cross-sectional data on 7,823 adults from 36 rural communities. Improved access and use are helpful, but evidence clearly indicates that combined health and social initiatives will be necessary to reduce inequalities in health status.     

A randomized trial comparing low-fat and low-carbohydrate diets matched for energy and protein

Several recent studies have found greater weight loss at 6 months among participants on a very-low-carbohydrate (VLC) weight-loss diet compared with a low-fat (LF) weight-loss diet. Because most of these studies were not matched for calories, it is not clear whether these results are caused by decreased energy intake or increased energy expenditure. It is hypothesized that several energy-consuming metabolic pathways are up-regulated during a VLC diet, leading to increased energy expenditure. The focus of this study was to investigate whether, when protein and energy are held constant, there is a significant difference in fat and weight loss when fat and carbohydrate are dramatically varied in the diet. The preliminary results presented in this paper are for the first four of six postmenopausal overweight or obese participants who followed, in random order, both a VLC and an LF diet for 6 weeks. Other outcome measures were serum lipids, glucose, and insulin, as well as dietary compliance and side effects. Our results showed no significant weight loss, lipid, serum insulin, or glucose differences between the two diets. Lipids were dramatically reduced on both diets, with a trend for greater triglyceride reduction on the VLC diet. Glucose levels were also reduced on both diets, with a trend for insulin reduction on the VLC diet. Compliance was excellent with both diets, and side effects were mild, although participants reported more food cravings and bad breath on the VLC diet and more burping and flatulence on the LF diet.     

Active Commuting to School,Physical Activity,and Behavior Problems Among Third‐Grade Children

BACKGROUND

We examined factors associated with active commuting to school and the relationships of active commuting and physical activity to child‐ and teacher‐reported internalizing and externalizing behavior problems in a sample of third graders.

METHODS

The study sample consisted of 13,166 third graders enrolled in the Early Childhood Longitudinal Study Kindergarten Class of 1998‐1999. “Active” commuters were children who walked to school and “passive” commuters were those who took the bus or were driven. Linear analyses evaluated differences in behavior problems by school commute, physical activity, and sports team participation after adjusting for sociodemographic, regional, and neighborhood factors.

RESULTS

Overall, 11% of children actively commuted. Type of commute differed by sociodemographics, region, urbanicity, school type, and neighborhood safety. Active commuters had less general physical activity participation and sports team participation. Commuting type and general physical activity were not associated with behavior problems, but sports team participation was associated with fewer child‐reported internalizing and externalizing behaviors as well as fewer teacher‐reported internalizing behaviors.

CONCLUSIONS

Our findings demonstrate the ongoing need for creating and maintaining physical activity programs (such as sports teams) among school‐aged children to optimize children's overall health and well‐being.

     

Oral facial clefts and gene polymorphisms in metabolism of folate/one‐carbon and vitamin A: a pathway‐wide association study

An increased risk of facial clefts has been observed among mothers with lower intake of folic acid or vitamin A around conception. We hypothesized that the risk of clefts may be further moderated by genes involved in metabolizing folate or vitamin A. We included 425 case‐parent triads in which the child had either cleft lip with or without cleft palate (CL/P) or cleft palate only (CPO), and no other major defects. We analyzed 108 SNPs and one insertion in 29 genes involved in folate/one‐carbon metabolism and 68 SNPs from 16 genes involved in vitamin A metabolism. Using the Triad Multi‐Marker (TRIMM) approach we performed SNP, gene, chromosomal region, and pathway‐wide association tests of child or maternal genetic effects for both CL/P and CPO. We stratified these analyses on maternal intake of folic acid or vitamin A during the periconceptional period. As expected with this high number of statistical tests, there were many associations with P‐values<0.05; although there were fewer than predicted by chance alone. The strongest association in our data (between fetal FOLH1 and CPO, P=0.0008) is not in agreement with epidemiologic evidence that folic acid reduces the risk of CL/P in these data, not CPO. Despite strong evidence for genetic causes of oral facial clefts and the protective effects of maternal vitamins, we found no convincing indication that polymorphisms in these vitamin metabolism genes play an etiologic role. Genet. Epidemiol. 2009. © 2008 Wiley Liss, Inc.     

School Personnel Perspectives on their School’s Implementation of a School-Based Suicide Prevention Program

Youth suicide is a national public health priority, with policymakers highlighting schools as an ideal setting in which to deliver suicide prevention programs. Over the past decade, the number of schools implementing such programs has grown substantially, yet little is known about how successfully such programs are being implemented. This study examines the implementation of a district-wide suicide prevention program through key informant interviews with school personnel. Schools with higher rates of implementing district protocols for at-risk students had an organized system to respond to at-risk students, a process for effectively responding to students who were at-risk for suicide, and strong administrative support. In contrast, schools that had lower rates of implementing district protocols relied on a handful of individuals for suicide prevention activities and had limited administrative support. Attention to organizational factors leading to successful implementation of school-based suicide prevention programs may enhance the role of schools in national adolescent suicide prevention efforts.     

CHANGES in SKIN TANNING ATTITUDES Fashion Articles and Advertisements in the Early 20th Century

Historical reviews suggest that tanning first became fashionable in the 1920s or 1930s. To quantitatively and qualitatively examine changes in tanning attitudes portrayed in the popular women''s press during the early 20th century, we reviewed summer issues of Vogue and Harper''s Bazaar for the years 1920, 1927, 1928, and 1929. We examined these issues for articles and advertisements promoting skin tanning or skin bleaching and protection. We found that articles and advertisements promoting the fashionable aspects of tanned skin were more numerous in 1928 and 1929 than in 1927 and 1920, whereas those promoting pale skin (by bleaching or protection) were less numerous. These findings demonstrate a clear shift in attitudes toward tanned skin during this period.NUMEROUS STUDIES HAVE linked exposure to ultraviolet (UV) light to both melanoma^1–4 and nonmelanoma skin cancers.^2–4 The incidence of skin cancers has risen dramatically over the past century,^5–7 and this is largely attributed to increased exposure to UV light from the sun. Despite public education initiatives aimed at preventing skin cancer,⁸ many individuals continue to tan, citing such reasons as the relationship between tanning and physical and emotional health, an active lifestyle, and physical beauty.⁹From a historical perspective, tanning as a fashion trend is a relatively new phenomenon, first noted in the 20th century. Earlier, pale skin was often perceived as a mark of beauty, wealth, and refinement, whereas tanned skin was considered to be typical of manual laborers.¹⁰ In the early 20th century, European and American women took precautions to maintain a light skin tone. Parasols and large hats were considered essential summer accessories.¹¹ Magazines in the early 20th century advertised powders that would conceal a tan as well as numerous bleach treatments, such as Bleachine Cream, which was featured in an advertisement by Elizabeth Arden in the July 1, 1920, issue of Vogue as “A mild but effective preparation for removing tan. Nourishing as well as whitening. Excellent for the hands.”¹² Toxic lead-based cosmetics, which date back to ancient Roman society, and other types of body powders were commonly used to lighten and augment fair skin during this era.^9,13Although it is well-known that social attitudes changed from sun protection to sun seeking during the first half of the 20th century, the exact year for such a cultural shift has remained obscure. Previous reviews on this subject suggest that the trend began in the late 1920s or early 1930s.^10,14 Magazines from the late 1920s reflect a clear shift in attitude, as illustrated in an article from a 1929 issue of Harper''s Bazaar: “Shall We Gild the Lily? There Is a Technique to a Good Tan—Whether by Fair Means or Fake!”¹⁵Open in a separate windowOpen in a separate windowJantzen swimsuit advertisement from (a) 1927 showing models with sun protection, including shawls, parasols, and wide-brimmed hats, and (b) 1929 depicting models in similar bathing suits, but now frolicking in the sun without sun protection.Illustrations by Frank Clark. Reprinted with permission of Jantzen.