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排序方式: 共有1013条查询结果,搜索用时 15 毫秒
41.
Christian BeardsleyRuelan Furtado M.B.B.S. Charles MosseSivakumar Gananadha F.R.A.C.S. James FergussonPhil Jeans F.R.A.C.S. Edwin Beenen 《American journal of surgery》2014
Background
A laparotomy is still considered mandatory for patients without previous abdominal surgery presenting with a small bowel obstruction (SBO) because of a perceived high incidence of underlying lesions. However, there is no evidence in literature to support this assumption. We analyzed the etiology of SBO in this subgroup of patients to establish the need for a mandatory laparotomy.Methods
A retrospective analysis was conducted over a 5-year period. Basic demographics, radiology results, operative findings, and outpatient investigations were analyzed.Results
Of 689 patients presenting with an SBO, a total of 62 patients, 9.0%, had a virgin abdomen. A known underlying disease (inflammatory bowel disease, malignancy) was the cause in 13 patients. The remaining 49 patients had adhesions in 75.5% and a newly diagnosed malignancy in 10.2% as a cause.Conclusions
Adhesions are by far the most likely cause of SBO in patients without previous abdominal surgery followed by a small number of newly diagnosed malignancies. Both prevalences are in equal proportion to patients with previous abdominal surgery. A trial of nonoperative management may therefore be justified. 相似文献42.
43.
Larissa Horta Esper Erikson Felipe Furtado 《European child & adolescent psychiatry》2014,23(10):877-889
To identify the demographic, psychological, and social maternal risk factors associated with the development of Fetal Alcohol Spectrum Disorders (FASD). A bibliographic search was conducted in PubMed, SciELO, Lilacs, Web of Knowledge, and PsycINFO. The Newcastle–Ottawa Quality Assessment Scale (NOS) was used to evaluate the quality of the studies with case–control design. Articles were selected based on their relevance and presentation of data related to statistical comparisons of at least one or more demographic, psychological, or social maternal risk factors for FASD. 738 references were identified, of which 15 met the criteria to be included in the present review. Mothers of FASD children tend to: be older at the time of birth of the affected child, present lower educational level, have other family relatives with alcohol abuse, have other children with FASD, present a pattern of little prenatal care and a distinguishing pattern of alcohol consumption (alcohol use before and during pregnancy, failure to reduce alcohol use during pregnancy, and frequent episodes of binge drinking). Application of the NOS scale of methodological quality indicated that 8 studies (53 %) met the criterion for selection, 4 (27 %) were suitable for the criterion for comparability and only 4 studies were suitable for the exposition criterion. Mothers of FASD children have a distinctive pattern of drinking and accumulate several social risk factors. Maternal age at birth of the child seems to accentuate the risk. There are, however, few controlled studies that are adequate according to the NOS requirements for methodological quality. Fewer are based on the verification of a theoretical model. Clinicians should be aware of the relevance of preventive assessment of FASD risk mothers. 相似文献
44.
Rodrigo Feliciano do Carmo Luydson Richardson Silva Vasconcelos Taciana Furtado Mendonça Maria do Socorro de Mendonça Cavalcanti Leila Maria Moreira Beltrão Pereira Patrícia Moura 《Human immunology》2014
Oxidative stress plays an important role on liver fibrosis progression in the course of hepatitis C virus (HCV) infection. Myeloperoxidase (MPO) is an enzyme released by neutrophils and macrophages, responsible for generating hypochlorous acid and reactive oxygen species (ROS) that may lead to liver injury in HCV infection. On the other hand, antioxidant enzymes such as manganese superoxide dismutase (SOD) controls ROS-mediated damage. The aim of the present study was to investigate the influence of MPO G-463A and SOD2 Ala16Val polymorphisms in the severity of liver fibrosis in individuals with chronic HCV infection. The present study included 270 patients with chronic HCV recruited from the Gastrohepatology Service of the Oswaldo Cruz University Hospital/Liver Institute of Pernambuco (Recife, Northeastern Brazil). All patients underwent liver biopsy, which was classified according METAVIR score. The SNPs were determined by real-time PCR. After multivariate analysis adjustment, the GG genotype of MPO and the presence of metabolic syndrome were independently associated with fibrosis severity in women (P = 0.025 OR 2.25 CI 1.10–4.59 and P = 0.032 OR 2.32 CI 1.07–5.01, respectively). The presence of the GG genotype seems to be a risk factor for fibrosis severity in women with HCV. 相似文献
45.
Betina Santos Tomaz Gabriela Carvalho Gomes Juliana Arcanjo Lino David Guabiraba Abitbol de Menezes Jorge Barbosa Soares Vasco Furtado Luiz Soares Júnior Maria do Socorro Quintino Farias Debora Lilian Nascimento Lima Eanes Delgado Barros Pereira Marcelo Alcantara Holanda 《Jornal brasileiro de pneumologia》2022,48(1)
46.
Cornejo-Olivas Mario Inca-Martinez Miguel Castilhos Raphael Machado Furtado Gabriel Vasata Mattos Eduardo Preusser Bampi Giovana Bavia Leistner-Segal Sandra Marca Victoria Mazzetti Pilar Saraiva-Pereira Maria Luiza Jardim Laura Bannach 《Cerebellum (London, England)》2020,19(2):208-215
The Cerebellum - Relative frequency of hereditary ataxias remains unknown in many regions of Latin America. We described the relative frequency in spinocerebellar ataxias (SCA) due to (CAG)n and to... 相似文献
47.
Marco Aurélio Lumertz Saffi Mariana Vargas Furtado Carisi Anne Polanczyk Márlon Munhoz Montenegro Ingrid Webb Josephson Ribeiro Cassio Kampits Alex Nogueira Haas Cassiano Kuchenbecker R?sing Eneida Rejane Rabelo-Silva 《World journal of cardiology》2015,7(1):26-30
Inflammation and endothelial dysfunction are linked to the pathogenesis of atherosclerotic disease. Recent studies suggest that periodontal infection and the ensuing increase in the levels of inflammatory markers may be associated with myocardial infarction, peripheral vascular disease and cerebrovascular disease. The present article aimed at reviewing contemporary data on the pathophysiology of vascular endothelium and its association with periodontitis in the scenario of cardiovascular disease. 相似文献
48.
49.
Sumit Thakar Sunil V. Furtado Nandita Ghosal A. S. Hegde 《Child's nervous system》2010,26(12):1819-1823
Introduction
Giant cavernous malformations (GCMs) constitute an uncommon entity in the diagnostic armamentarium of the neurosurgeon. We report a 3-year-old boy with a GCM in the peri-trigonal region and review 13 other paediatric cases previously reported in literature. 相似文献50.
Milena B. Furtado Christine Biben Hidetaka Shiratori Hiroshi Hamada Richard P. Harvey 《Developmental dynamics》2011,240(1):195-203
To aid in detection and tracking of cells targeted by the left‐right (LR) pathway in the heart throughout morphogenesis, expression from a Pitx2c‐lacZ transgene (P2Ztg) was analysed in detail. β‐galactosidase expression from P2Ztg was robust, allowing reliable visualisation of low‐level Pitx2c expression, and was virtually entirely dependent upon NODAL signalling in the heart. P2Ztg showed expression in trabecular and septal, as well as non‐trabecular, myocardium, and a strong expression bias in myocardium associated with individual endocardial cushions of the atrioventricular canal and outflow tract, which are essential for cardiac septation. Expression on the ventral surface of the outflow tract evolved to a specific stripe that could be used to track the future aorta during outflow tract spiralling and remodelling. Our data show that the P2Ztg transgene is a useful resource for detection of molecular disturbances in the LR cascade, as well as morphogenetic defects associated with other cardiac congenital disorders. Developmental Dynamics, 2011. © 2010 Wiley‐Liss, Inc. 相似文献