全文获取类型
收费全文 | 4961篇 |
免费 | 440篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 47篇 |
儿科学 | 124篇 |
妇产科学 | 85篇 |
基础医学 | 692篇 |
口腔科学 | 165篇 |
临床医学 | 534篇 |
内科学 | 944篇 |
皮肤病学 | 50篇 |
神经病学 | 437篇 |
特种医学 | 247篇 |
外科学 | 581篇 |
综合类 | 86篇 |
一般理论 | 16篇 |
预防医学 | 607篇 |
眼科学 | 85篇 |
药学 | 396篇 |
中国医学 | 6篇 |
肿瘤学 | 307篇 |
出版年
2023年 | 32篇 |
2022年 | 33篇 |
2021年 | 105篇 |
2020年 | 60篇 |
2019年 | 72篇 |
2018年 | 83篇 |
2017年 | 73篇 |
2016年 | 57篇 |
2015年 | 85篇 |
2014年 | 120篇 |
2013年 | 173篇 |
2012年 | 212篇 |
2011年 | 227篇 |
2010年 | 149篇 |
2009年 | 146篇 |
2008年 | 240篇 |
2007年 | 293篇 |
2006年 | 269篇 |
2005年 | 252篇 |
2004年 | 232篇 |
2003年 | 233篇 |
2002年 | 209篇 |
2001年 | 121篇 |
2000年 | 113篇 |
1999年 | 104篇 |
1998年 | 81篇 |
1997年 | 51篇 |
1996年 | 56篇 |
1995年 | 41篇 |
1994年 | 31篇 |
1993年 | 41篇 |
1992年 | 74篇 |
1991年 | 95篇 |
1990年 | 96篇 |
1989年 | 91篇 |
1988年 | 87篇 |
1987年 | 73篇 |
1986年 | 82篇 |
1985年 | 63篇 |
1984年 | 63篇 |
1983年 | 52篇 |
1982年 | 30篇 |
1981年 | 44篇 |
1980年 | 49篇 |
1979年 | 45篇 |
1978年 | 45篇 |
1977年 | 37篇 |
1976年 | 30篇 |
1973年 | 28篇 |
1969年 | 32篇 |
排序方式: 共有5409条查询结果,搜索用时 15 毫秒
71.
Genomic characterization of pediatric B‐lymphoblastic lymphoma and B‐lymphoblastic leukemia using formalin‐fixed tissues 下载免费PDF全文
72.
73.
74.
John P. Micha Mark A. Rettenmaier Matthew Clark Jim C. Hu Miles Chang John V. BrownIII Bram H. Goldstein 《Gynecological surgery》2008,5(1):49-51
Persistent uterine prolapse with secondary acute renal failure is a very uncommon event. We report the case of a 77-year-old
woman with a 5-year history of uterine prolapse. She was referred to our gynecologic oncology service for 3rd degree uterine
prolapse and was found to have bilateral hydronephrosis and acute renal insufficiency. The patient was fitted for a pessary
to manage the uterine prolapse, which resulted in resolution of her hydronephrosis and renal insufficiency. Prompt assessment
with nephrology consultation and pessary placement for patients with 3rd degree genital prolapse is imperative to ensure that
irreversible renal complications do not manifest themselves.
This study was supported by a grant from the Women’s Cancer Research Foundation. 相似文献
75.
Lawrence GC Rettenmaier MA Heinemann S Chang M Goldstein BH 《Archives of gynecology and obstetrics》2008,278(4):383-386
Chorioangiomas are common placental neoplasms that are primarily asymptomatic, but the larger subtypes have a variable presentation and can result in severe pregnancy complications. We report a case of a pregnant patient who presented with a 10 x 12 x 10 cm placental chorioangioma at 32 weeks, despite an unremarkable ultrasound at 28 weeks. Since these more substantial chorioangiomas can induce fetal mortality, close surveillance with perinatology and neonatology consultation is necessary to enhance the probability of a favorable patient prognosis. 相似文献
76.
Fedor Kryuchkov Alison Robertson Elizabeth M. Mudge Christopher O. Miles Soetkien Van Gothem Silvio Uhlig 《Toxins》2022,14(6)
Ciguatera poisoning is a global health concern caused by the consumption of seafood containing ciguatoxins (CTXs). Detection of CTXs poses significant analytical challenges due to their low abundance even in highly toxic fish, the diverse and in-part unclarified structures of many CTX congeners, and the lack of reference standards. Selective detection of CTXs requires methods such as liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) or high-resolution MS (LC–HRMS). While HRMS data can provide greatly improved resolution, it is typically less sensitive than targeted LC–MS/MS and does not reliably comply with the FDA guidance level of 0.1 µg/kg CTXs in fish tissue that was established for Caribbean CTX-1 (C-CTX-1). In this study, we provide a new chemical derivatization approach employing a fast and simple one-pot derivatization with Girard’s reagent T (GRT) that tags the C-56-ketone intermediate of the two equilibrating C-56 epimers of C-CTX-1 with a quaternary ammonium moiety. This derivatization improved the LC–MS/MS and LC–HRMS responses to C-CTX-1 by approximately 40- and 17-fold on average, respectively. These improvements in sensitivity to the GRT-derivative of C-CTX-1 are attributable to: the improved ionization efficiency caused by insertion of a quaternary ammonium ion; the absence of adduct-ions and water-loss peaks for the GRT derivative in the mass spectrometer, and; the prevention of on-column epimerization (at C-56 of C-CTX-1) by GRT derivatization, leading to much better chromatographic peak shapes. This C-CTX-1–GRT derivatization strategy mitigates many of the shortcomings of current LC–MS analyses for C-CTX-1 by improving instrument sensitivity, while at the same time adding selectivity due to the reactivity of GRT with ketones and aldehydes. 相似文献
77.
78.
C T Henderson L S Trumbore S Mobarhan R Benya T P Miles 《Journal of the American College of Nutrition》2013,32(3):309-325
This study examines nutritional status and clinical outcomes, including pressure ulcers and death in 40 chronically tube-fed long-term care patients. Anthropometric, biochemical, clinical and dietary data were collected over a 3-month period, with follow-up of mortality at 1 year. Subjects' functional and cognitive status was generally poor. Adequate calories and protein were provided, with sample means exceeding standard means for energy, protein and micronutrients. Still, subjects showed weight loss and severe depletion of lean and fat body mass. Mean serum protein and micronutrient status measures were in the low normal range. Hemoglobin, hematocrit, and serum zinc and carotenoid levels were below normal in a sizable proportion of patients. Pressure ulcers were present in 65% of patients. Weight loss was associated with longer time on tube feeding and more pressure ulcers. Negative correlations with ulcer number were observed for cholesterol, albumin, zinc, retinol, alpha-tocopherol and iron. This study shows that despite administration of apparently adequate formula, micronutrient deficiencies and marasmic malnutrition exist in chronically ill patients. Causes may include the combined effects of chronic disease, sepsis, immobility, and severe neurologic deficits. Clinical outcomes may be expressions of an organism-wide diminution of protein synthesis, the cause of which is unknown. For clinical management, serial measures of weight, albumin, cholesterol, hemoglobin and hematocrit are recommended. Future research must address the many subsets of the population of chronically tube-fed patients. 相似文献
79.
80.