全文获取类型
收费全文 | 190篇 |
免费 | 15篇 |
专业分类
儿科学 | 3篇 |
妇产科学 | 1篇 |
基础医学 | 10篇 |
口腔科学 | 3篇 |
临床医学 | 16篇 |
内科学 | 32篇 |
神经病学 | 57篇 |
特种医学 | 7篇 |
外国民族医学 | 2篇 |
外科学 | 27篇 |
综合类 | 11篇 |
一般理论 | 1篇 |
预防医学 | 11篇 |
眼科学 | 4篇 |
药学 | 7篇 |
中国医学 | 1篇 |
肿瘤学 | 12篇 |
出版年
2023年 | 2篇 |
2022年 | 6篇 |
2021年 | 7篇 |
2020年 | 7篇 |
2019年 | 4篇 |
2018年 | 6篇 |
2017年 | 4篇 |
2016年 | 4篇 |
2015年 | 3篇 |
2014年 | 7篇 |
2013年 | 14篇 |
2012年 | 30篇 |
2011年 | 23篇 |
2010年 | 9篇 |
2009年 | 9篇 |
2008年 | 11篇 |
2007年 | 15篇 |
2006年 | 14篇 |
2005年 | 10篇 |
2004年 | 5篇 |
2003年 | 3篇 |
2002年 | 2篇 |
2000年 | 1篇 |
1998年 | 1篇 |
1996年 | 1篇 |
1991年 | 1篇 |
1990年 | 2篇 |
1983年 | 1篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1971年 | 1篇 |
排序方式: 共有205条查询结果,搜索用时 15 毫秒
81.
Canadian Journal of Anesthesia/Journal canadien d'anesthésie - 相似文献
82.
Sohaib Ashraf Shoaib Ashraf Moneeb Ashraf Muhammad Ahmad Imran Larab Kalsoom Uzma N. Siddiqui Iqra Farooq Rutaba Akmal Muhammad Kiwan Akram Sidra Ashraf Muhammad Ghufran Nighat Majeed Zaighum Habib Sundas Rafique Zain-ul -Abdin Shahroze Arshad Muhammad Sarmad Shahab Sohail Ahmad Hui Zheng Ali Rafique Mirza Sibgha Zulfiqar Muhamad Imran Anwar Ayesha Humayun Talha Mahmud Qazi Abdul Saboor Ali Ahmad Muhammad Ashraf Mateen Izhar DOCTORS LOUNGE consortium 《Phytotherapy research : PTR》2023,37(2):627-644
Until now, no specific and effective treatment exists for coronavirus disease 2019 (COVID-19). Since honey and Nigella sativa (HNS) have established antiviral, antibacterial, antiinflammatory, antioxidant, and immunomodulatory properties, we tested their efficacy for this disease in a multicenter, placebo-controlled, and randomized clinical trial at four medical care facilities in Pakistan. RT-PCR confirmed COVID-19 adults showing moderate or severe disease were enrolled in the trial. Patients were randomly assigned in a 1:1 ratio to receive either honey (1 g kg−1 day−1) and Nigella sativa seeds (80 mg kg−1 day−1) or a placebo for up to 13 days along with standard care. The outcomes included symptoms' alleviation, viral clearance, and 30-day mortality in the intention-to-treat population. Three hundred and thirteen patients, 210 with moderate and 103 with severe disease, underwent randomization from April 30 to July 29, 2020. Among the moderate cases, 107 were assigned to HNS, whereas 103 were assigned to the placebo group. Among the severe cases, 50 were given HNS, and 53 were given the placebo. HNS resulted in ~50% reduction in time taken to alleviate symptoms as compared to placebo (moderate cases: 4 vs. 7 days, Hazard Ratio [HR]: 6.11; 95% Confidence Interval [CI]: 4.23–8.84, p < 0.0001 and for severe cases: 6 vs. 13 days, HR: 4.04; 95% CI: 2.46–6.64; p < 0.0001). HNS also cleared the virus earlier than placebo in both moderate cases (6 vs. 10 days, HR: 5.53; 95% CI: 3.76–8.14, p < 0.0001) and severe cases (8.5 vs. 12 days, HR: 4.32; 95% CI: 2.62–7.13, p < 0.0001). HNS further led to a better clinical score on day 6 with normal activity resumption in 63.6% vs. 10.9% among moderate cases (OR: 0.07; 95% CI: 0.03–0.13, p < 0.0001) and hospital discharge in 50% versus 2.8% in severe cases (OR: 0.03; 95% CI: 0.01–0.09, p < 0.0001). In severe cases, the mortality rate was less than 1/4th in the HNS group than in placebo (4% vs. 18.87%, OR: 0.18; 95% CI: 0.02–0.92, p = 0.029). No HNS-related adverse effects were observed. HNS, compared with placebo, significantly improved symptoms, expedited viral load clearance, and reduced mortality in COVID-19 patients. This trial was registered on April 15, 2020 with ClinicalTrials.gov Identifier: NCT04347382. 相似文献
83.
Objectives
To establish the efficacy of ultrasound (US) of the abdomen as a diagnostic test in Typhoid. To determine the ultrasound diagnostic criteria in cases of Typhoid. 相似文献84.
Mateen H. Arastu J. Vijayaraghavan H. Chissell J. B. Hull J. H. Newman J. R. Robinson 《Knee surgery, sports traumatology, arthroscopy》2009,17(10):1178-1183
Concerned by a perceived high revision rate, we retrospectively reviewed the survivorship of a series of 43 cemented, medial,
mobile-bearing Preservation unicompartmental knee replacements implanted during a 2-year period at a single institution. The
initial post-operative AP and lateral radiographs were independently assessed to test the hypothesis that suboptimal implantation
of the prosthesis was responsible for early failure. An X-ray scoring system based on the criteria for assessing the Oxford
mobile-bearing unicompartmental knee replacement was devised. The components of this score included assessment of prosthesis
alignment, sizing and cementation. Nine (21%) LCS Preservation mobile-bearings prostheses had required revision at a mean
of 22 months post-implantation. The commonest causes for failure were pain (44%) and tibial component loosening (33%). Analysis
of post-operative radiographs showed no difference (n.s.) between the compound error scores for the revised and the surviving
prostheses. No particular surgical error was identifiable leading to subsequent need for revision. The high failure rates
shown in this study have led us to cease using this implant. The clinical relevance of this study is that the captive running
track of the LCS mobile-bearing prosthesis may over constrain the meniscal component leading to early failure. 相似文献
85.
Background
Oral poliovirus vaccine (OPV) remains the vaccine-of-choice for routine immunization and supplemental immunization activities (SIAs) to eradicate poliomyelitis globally. Recent data from India suggested lower than expected immunogenicity of an OPV birth dose, prompting a review of the immunogenicity of OPV or inactivated poliovirus vaccine (IPV) when administered at birth.Methods
We evaluated the seroconversion and reported adverse events among infants given a single birth dose (given ≤7 days of life) of OPV or IPV through a systematic review of published articles and conference abstracts from 1959 to 2011 in any language found on PubMed, Google Scholar, or reference lists of selected articles.Results
25 articles from 13 countries published between 1959 and 2011 documented seroconversion rates in newborns following an OPV dose given within the first seven days of life. There were 10 studies that measured seroconversion rates between 4 and 8 weeks of a single birth dose of TOPV, using an umbilical cord blood draw at the time of birth to establish baseline antibody levels. The percentage of newborns who seroconverted at 8 weeks range from 6–42% for poliovirus type 1, 2–63% for type 2, and 1–35% for type 3. For mOPV type 1, seroconversion ranged from 10 to 76%; mOPV type 3, the range was 12–58%; and for the one study reporting bOPV, it was 20% for type 1 and 7% for type 3. There were four studies of IPV in newborns with a seroconversion rate of 8–100% for serotype 1, 15–100% for serotype 2, and 15–94% for serotype 3, measured at 4–6 weeks of life. No serious adverse events related to newborn OPV or IPV dosing were reported, including no cases of acute flaccid paralysis.Conclusions
There is great variability of the immunogenicity of a birth dose of OPV for reasons largely unknown. Our review confirms the utility of a birth dose of OPV, particularly in countries where early induction of polio immunity is imperative. IPV has higher seroconversion rates in newborns and may be a superior choice in countries which can afford IPV, but there have been few studies of an IPV dose for newborns. 相似文献86.
Mateen FJ 《Neurocritical care》2011,15(3):593-598
Neurocritical illness heavily burdens the developing world. In spite of a lack of resources for population-based health in
most developing countries, there is an increasing demand for resource-intense strategies for acute neurological care. Factors
including rising individual incomes in emerging economies, need for neurointensive care in humanitarian emergencies, growth
of private hospitals, the rising burden of noncommunicable disease, and the practice of neurocritical care by specialists
outside of neurology are discussed. Possible steps to improve the global practice of neurocritical care include: (1) emphasis
on prevention of neurocritical illness through traffic safety and adequate outpatient treatment; (2) standardization of training
requirements and skill sets; (3) guidelines on cost-effective measures including medications, equipment, and devices; (4)
strengthening of surveillance systems and registries for both noncommunicable and communicable neurological diseases; (5)
expanded use of teleneurology; (6) educational exchanges of neurointensive health care workers; and (7) monitoring of neurological
intensive care unit death rates due to nosocomial infections, neurological disease, and other causes. A summary of reported
mortality rates among neurocritically ill patients in African countries in recent years is provided as an illustrative example. 相似文献
87.
Sayed SI Dutta S Mateen S Kazi R Jagade M 《Journal of the Indian Medical Association》2011,109(4):270-271
A vibrant health research industry is an indispensible asset for societal development. Health research focus and output in India is sadly not at par with the magnitude and distribution of the prevalent disease burden. In the current scenario of the ever evolving Indian public health sector, the balancing of research efforts between different competing fields, especially when resources are meagre, is a delicate one and quite typical of the problems anticipated in developing countries. To progress, the nation's clinical health research needs good quality, authentic and relevant research in the varied aspect of public health. Rhetoric or theoretical concepts alone cannot move the health status and research forward in this country. Evidence and evidence based medicine have revitalised the academic aspects of the public health sector. But, its up to the Indian policy makers, administrators and medical professionals to assure that the vast research opportunity this country offers is exploited to its maximum potential. 相似文献
88.
Mateen FJ Zubkov A Muralidharan R Petty G Winters J 《Neurology》2011,77(17):e101; author reply e103-e101; author reply e104
89.
90.
Mateen FJ Shuaib A 《The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques》2007,34(3):270-279
The antiplatelet drugs, commonly used in the prevention and treatment of cerebrovascular disease, possess a number of effects that are independent of direct antiplatelet actions. Beneficial and detrimental effects both occur. The endothelium is an important mediator of these non-antiplatelet effects. We performed a literature search to locate articles related to acetylsalicylic acid (aspirin), clopidogrel, ticlopidine, and dipyridamole and the interactions of these medications with the endothelium. The role of each of the above medications is explored in relation to vasodilation, inflammation, oxidation, platelet-leukocyte interactions, and thrombogenic tendency via platelet-vessel wall interactions. 相似文献