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991.
992.
Lewis MA Yaqoob NA Emanuel C Potts AJ 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,103(4):483-486
Linear IgA disease (LAD) is a rare acquired autoimmune bullous disorder, characterized by linear deposition of IgA along the dermoepidermal basement membrane zone. The clinical presentation of LAD consists of vesiculobullous lesions affecting the skin and mucosal surfaces. The present case report presents a rare presentation of this vesiculobullous disorder. Although more than 50% of LAD patients present with oral lesions, there are few reported cases of involvement of the mouth as the sole manifestation. A 79-year-old female presented with a sore mouth and erosions affecting the palate. The symptoms resolved following the provision of mycophenolate, an antiproliferative immunosuppressant which has not previously appeared to have been reported in the long-term successful management of linear IgA disease limited to the mouth. We found that mycophenolate is a useful adjunct to the successful treatment of oral linear IgA when the uses of other immunosuppressants are contraindicated. 相似文献
993.
da Silva CE da Silva ID Cerri A Weckx LL 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(4):497-500
Oncogenic human papillomaviruses (HPVs) are important agents in the genesis of gynecological cancer, and have also been implied in the genesis of oral cancer. With the purpose of evaluating the relationship between HPV and squamous cell carcinoma (SCC) of the tongue, a case-control study was performed. Fifty white male patients who were smokers and had the histological diagnosis of SCC of the tongue were selected. The control group was composed of 10 matched patients with no clinical evidence of tongue lesions. Polymerase chain reaction (PCR) was used to detect the presence of HPV genome in fresh-frozen tissue specimens from SCC of the tongue margin. Thirty-seven patients (74%) had a positive PCR for oncogenic papillomavirus, and only 1 specimen (10%) of the control group was positive for nononcogenic papillomavirus. Based on the statistical analysis of this study there was a 25.6% higher risk for SCC of the tongue to harbor oncogenic HPV than the healthy control tongue tissue. 相似文献
994.
Thiago Roberto Lima Romero Raquel Rodrigues Soares Santos Marina Gomes Miranda e Castor Júlia Alvarenga Petrocchi Luciana Souza Guzzo Andre Klein Igor Dimitri Gama Duarte 《Pharmacological reports : PR》2018,70(4):784-788
Background
The aim of this study was to investigate this involvement in not inflammatory model of pain and which opioid receptor subtype mediates noradrenaline-induced peripheral antinociception. Noradrenaline is involved in the intrinsic control of pain-inducing pro-nociceptive effects in the primary afferent nociceptors. However, inflammation can induce various plastic changes in the central and peripheral noradrenergic system that, upon interaction with the immune system, may contribute, in part, to peripheral antinociception.Methods
Hyperalgesia was induced by intraplantar injection of prostaglandin E2 (PGE2, 2 μg) into the plantar surface of the right hind paw and the paw pressure test to evaluated the hyperalgesia was used. Noradrenaline (NA) was administered locally into right hind paw of Wistar rat (160–200 g) alone and after either agents, α2-adrenoceptor antagonist yohimbine, α1-adrenoceptor antagonist prazosin, β-adrenoceptor antagonist propranolol, μ-opioid antagonist clocinnamox, δ-opioid antagonist naltrindole and κ-opioid antagonist nor-binaltorfimina. In addition, the enkephalinase inhibitor bestatin was administered prior to NA low dose.Results
Intraplantar injection of NA induced peripheral antinociception against hyperalgesia induced by PGE2. This effect was reversed, in dose dependent manner, by intraplantar injection of yohimbine, prazosin, propranolol, clocinnamox and naltrindole. However, injection of nor-binaltorfimina did not alter antinociception of NA after PGE2 hyperalgesia. Bestatin intensified the antinociceptive effects of low-dose of NA.Conclusion
Besides the α2-adrenoceptor, the present data provide evidence that, in absence of inflammation, NA activating α1 and β-adrenoceptor induce endogenous opioid release to produce peripheral antinociceptive effect by μ and δ opioid receptors. 相似文献995.
Carboni Rosadélia Malheiros Gonçalves Marcela Leticia Leal Tacla Elaine Marlene Silva Daniela Fátima Teixeira Bussadori Sandra Kalil Fernandes Kristianne Porta Santos Horliana Anna Carolina Ratto Tempestini Mesquita-Ferrari Raquel Agnelli 《Lasers in medical science》2022,37(3):1881-1890
Lasers in Medical Science - The benefits of photobiomodulation (PBM) applied to wounds are well-described in the literature; however, its effects in skin graft donor sites have been poorly studied.... 相似文献
996.
Ibarra Ana Melissa Ccopa Cecatto Rebeca Boltes Motta Lara Jansiski dos Santos Franco Adriana Lino de Fátima Teixeira da Silva Daniela Nunes Fabio Daumas Hamblin Michael R Rodrigues Maria Fernanda Setúbal Destro 《Lasers in medical science》2022,37(3):1441-1470
Lasers in Medical Science - This narrative review aimed to evaluate the effectiveness of PDT in early or advanced squamous cell carcinoma of the head and neck (SCCHN). Scopus, MEDLINE/PubMed, and... 相似文献
997.
Marzano Lucas Alexandre Santos Batista Joao Pedro Thimotheo de Abreu Arruda Marina de Freitas Cardoso Mara Glria de Barros Joo Lus Vieira Monteiro Moreira Janana Matos Liu Priscila Menezes Ferri Teixeira Antnio Lcio Simes e Silva Ana Cristina de Miranda Aline Silva 《Neurosurgical review》2022,45(1):167-197
Neurosurgical Review - Traumatic brain injury (TBI) is the main cause of pediatric trauma death and disability worldwide. Recent studies have sought to identify biomarkers of TBI for the purpose of... 相似文献
998.
Baad Vanessa M. A. Bezerra Louise R. de Holanda Narriane C. P. dos Santos Ana C. O. da Silva Amanda A. M. Bandeira Francisco Cavalcante Taisy C. F. 《Obesity surgery》2022,32(12):3830-3838
Obesity Surgery - Evaluate the differences between surgical techniques in the modifications of body composition and the interference in skeletal muscle health, risk of sarcopenia, and reduced... 相似文献
999.
Genario Santos Jessica Gasca Raymundo Parana Vinicius Nunes Maria Schinnoni Inmaculada Medina‐Caliz Maria Rosario Cabello Maria Isabel Lucena Raul J. Andrade 《Phytotherapy research : PTR》2021,35(1):6-19
Hepatotoxicity related to HDS is a growing global health issue. We have undertaken a systematic review of published case reports and case series from LA from 1976 to 2020 to describe the clinical features of HDS related hepatotoxicity in this region. We search in PubMed, Web of Science, Scopus and specific LA databases according to PRISMA guidelines. Only HILI cases published in LA that met criteria for DILI definition were included. Duplicate records or reports that lacked relevant data that precluded establishing causality were excluded. Finally, 17 records (23 cases) were included in this review. Centella asiatica, Carthamus tinctorius, and Herbalife® were the most reported HDS culprit products, the main reason for HDS consumption was weight loss. The clinical characteristics of HDS hepatotoxicity in our study were compared to those of other studies in the USA, Europe and China showing a similar signature with predominance of young females, hepatocellular damage, a high rate of ALF and mortality, more frequent inadvertent re‐challenge and chronic damage. This study underscores the challenge in causality assessment when multi‐ingredients HDS are taken and the need for consistent publication practice when reporting hepatotoxicity cases due to HDS, to foster HDS liver safety particularly in LA. 相似文献