泌尿外科手助腹腔镜手术的进展

外科手术发展至今可分为三代:第一代为开放手术(open surgery);第二代为腹腔镜手术(laparoscop-ic surgery),其又可分为三个技术平台,包括标准腹腔镜手术(purelaparoscopic surgery或standardlap-aroscopic surgery)、手助腹腔镜手术(hand-assistedlaparoscopic surgery)和针式     

浅谈胡澍手校本《素问》的文献版本价值

清末经学家和小学家胡澍把《素问》作为子书之一，博采众本，悉心校勘，以小学的方法进行专门研究，撰成《素问校义》，为研习《内经》不可不读之书。通过对天津中医药大学图书馆所藏胡澍手校本《重广补注黄帝内经素问》的考证，发现胡澍校勘所据底本一直被误作宋本，而实是明顾从德影宋刻本．校勘工作历时数年，手校本《素问》留有胡澍悉心对校后所做出的千余条校语，可惜草创未就，他便英年早逝。手校本这第一手资料，对研究胡澍的治学思想和《素问校义》的成书过程，学习和掌握知识，传承弘扬学术，都具有重女的文献参考价值。     

Computerized tomography observation of a calcifying cystic odontogenic tumor with an odontoma: case report.

The calcifying cystic odontogenic tumor is a rare benign odontogenic lesion. This report documents a case of this lesion associated with odontoma arising from the anterior maxilla in a 14-year-old boy. The diagnosis was confirmed based on computerized tomography findings, which clearly depicted the internal structures obscured in conventional images.     

几丁糖-聚乳酸复合生物材料神经导管的预构

目的:神经导管修复周围神经损伤,作为一种新的周围神经损伤修复方法显示出广阔的应用前景.本实验将几丁糖、聚乳酸两种材料结合,试图研制出一种理化性质、生物相容性俱佳的神经导管材料.材料和方法:第一部分:几丁糖-聚乳酸复合生物材料的研制及其物理性能测试.将2%几丁糖与0.5%聚乳酸以不同的比例化合反应后制成导管.力学实验检测不同比例制成导管的强度和韧性,根据实验结果选择最佳比例,并进一步测定该复合材料的其它物理性能.第二部分:几丁糖-聚乳酸复合生物材料的生物相容性检测.用细胞增殖度实验评价新材料的细胞毒性.用最大剂量法豚鼠致敏实验测试新材料致敏性.结果:2%几丁糖与0.5%聚乳酸以5∶1(体积比)比例混合反应制成的新材料,其各项物理性能符合制备神经导管要求.在细胞毒性实验中,复合材料浸提液培养2天后及5天后,细胞相对增殖度(RGR)为83.67%,96.41%.致敏实验显示新复合材料浸提液致敏率为0级.实验证明新复合材料无细胞毒性、无致敏性.结论:几丁糖、聚乳酸通过适当比例结合制作的复合生物材料具有良的物理性能及生物相容性,符合制备神经导管的理化要求.     

显微镜下直切口锁孔微创治疗高血压性脑出血

目的探讨显微镜下直切口锁孔微创治疗高血压性脑出血的价值。方法根据CT提示血肿在头皮的投影设计手术切口部位，通过4～5cm皮肤直切口，直径2cm的骨窗，切开皮层到达血肿腔清除血肿。结果血肿完全清除17例，18例清除率达到90％，4例清除率达到80％。术后再出血2例。4例术后3周内死亡：2例死于循环呼吸功能衰竭，1例死于脑干功能衰竭，1例死于消化道出血，手术死亡率10．2％（4／39）。35例随访0．5—3年，平均2．1年，术后6个月ADL分级：1级9例，2级12例，3级9例，4级4例，5级1例，死亡4例。结论显微镜下直切口锁孔微创技术是一种快速、有效和安全的治疗高血压性脑出血的手术方法，可以解除血肿的占位压迫效应，有效止血，防止再出血，效果满意。     

Assessment of global and regional left ventricular twist and displacement in anterior myocardial infarction using 2-dimensional strain imaging

The recent development of 2-dimensional strain (2D strain) imaging can provide a powerful alternative for assessing left ventricular (LV) torsion. This study was conducted to evaluate the global and regional left ventricular twist by 2D strain in patients with anterior wall myocardial infarction (AMI). A total of 55 AMI patients were divided into two groups according to their ejection fraction (EF) values (group A: LVEF ⩾ 50%; group B: LVEF < 50%), and 35 normal people served as the control group. Using 2-dimensional strain software, global and regional LV rotation and displacement were obtained at two planes. Compared with the control group, patients of group A showed reduced peak LV twist of the anterior and anterior-septal wall (9.26±1.89 vs 10.74±2.67; 9.71±1.71 vs 11.36±2.29, both P < 0.05), but the radial displacement and global twist were maintained (P > 0.05). Differently, regional and global LV twist and radial displacement in patients of group B deceased significantly, especially in the anterior and anterior-septal wall, as compared with patients in the control or group A (both P < 0.05). Moreover, a strong correlation was noted between peak twist and radial displacement; the twist-displacement loop was markedly distorted in patients of group B. This study demonstrated that 2D strain has a potential ability for quantification of left ventricular global and segment twist and radial displacement in patients with coronary artery disease.     

Systemic Antiinflammatory Corticosteroid Reduces Mechanical Pain Behavior, Sympathetic Sprouting, and Elevation of Proinflammatory Cytokines in a Rat Model of Neuropathic Pain

Background: Chronic pain models are commonly defined as either nerve-injury or inflammation models, but recent work suggests inflammatory processes are important in nerve injury-induced pain.

Methods: In the rat spinal nerve ligation model, the authors examined effects of systemic corticosteroid triamcinolone acetonide (TA) on the cytokine protein profile and sympathetic sprouting in the axotomized sensory ganglia, excitability of sensory neurons, and mechanical sensitivity.

Results: By postoperative day 3, marked increases (5- to 16-fold) in monocyte chemoattractant protein-1, growth-related oncogene (GRO/KC or CXCL1), and interleukin (IL)-6 were observed, whereas IL-4 and IL-2 levels fell more than fourfold. The increased cytokines and number of sympathetic basket formations in the sensory ganglia were reduced toward normal values by TA given starting at the time of injury. Interleukin-4 and IL-2 levels were not restored by TA. Systemic TA also reduced the firing rate and incidence of bursting activity, but not the overall incidence of spontaneous activity, in large- and medium-sized neurons. Mechanical hypersensitivity on postoperative day 3 was reduced by TA, and some effect could still be observed 4 days after cessation of TA. However, starting TA at day 7 was ineffective.     

卵巢浆液性囊腺癌的CT诊断（附三例报告）

作者报告了三例经手术病理证实的卵巢浆液性囊腺癌的临床及CT表现，分析了其中2例经化疗后转移的CT特点，CT主要表现为：（1）盆腔内囊实性肿块，部分肿块内有钙化；（2）肉膜饼状转移。（3）脏器的浆膜及系膜播散；（4）钙化性转移，CT对本病的诊断与分期均优于临床检查。     

荧光定量聚合酶链反应在尖锐湿疣诊断中的应用

目的　探讨荧光定量聚合酶链反应 (FQ - PCR)对尖锐湿疣 (CA )的诊断价值。方法　 FQ- PCR检测病理确诊的 CA患者 36份标本和健康人 84份标本 ;FQ- PCR及病理诊断同期检测临床送检病例 2 73份标本 ,并做诊断性试验评价。结果　 36例病理确诊的 CA患者 HPV6和 HPV11的 DNA FQ- PCR全部阳性 ,平均拷贝数为 1.0× 10 7± 1.0× 10 2 / m l;84例健康人 FQ- PCR全部阴性 ,平均拷贝数为 3× 10± 2× 10 / ml。 FQ- PCR与病理诊断符合率为 10 0 % ,CA患者与健康人拷贝数的差异有显著性 (P<0 .0 5 )。FQ- PCR与病理诊断对比得出 :灵敏度为 10 0 % ,特异度为 92 % ,误诊率为 0 .0 8,漏诊率为 0 ,准确度为 98.9% ,阳性预测值为 98.8% ,阴性预测值为 10 0 % ,阳性似然比为 12 .5 ,阴性似然比为 0。结论　 FQ - PCR能准确定量 ,灵敏度高 ,特异性强 ,快速 ,简便 ,可作为尖锐湿疣早期诊断的指标     

聚对苯乙炔（PPV）及其衍生物的研究进展

评价了ＰＰＶ系列衍生物的电学性质、非线性光学性质及其应用。