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991.
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994.
J Koike T Ishido N Takiguchi H Tachi J Tazawa M Nishimura K Kawada H Fujiwara 《Internal medicine (Tokyo, Japan)》1992,31(1):86-90
We report a case of malignant lymphoma presenting as the superior vena cava syndrome. This case is very interesting since both adenocarcinoma mucocellulare scirrhosum, Borrman type IV, and lymphoma were present in the stomach, forming colliding neoplasms. Rather than systemically disseminated, the lymphoma cells were localized in the stomach, the intestine, a few perigastric lymph nodes and in a mediastinal mass, which may have constituted a neoplastic thymus invaded by lymphoma cells from the stomach. The unique occurrence of the histological combination as gastric colliding neoplasms is discussed. 相似文献
995.
Taijiro Ishiyama Shinji Nakamura Yoshihisa Akimoto Michiaki Koike Shigeru Tomoyasu Nobuyoshi Tsuruoka Yaeko Murata Tadatsugu Sato† Yoshihisa Wakabayashi† Shyozo Chiba† 《British journal of haematology》1994,86(3):483-489
Summary. To study the pathogenesis of multicentric Castleman's disease (MCD), IL-6 producing cells and immune function were investigated in four MCD patients. The expression of IL-6 mRNA in one MCD lymph node was analysed by in situ hybridization. IL-6 mRNA expressing cells were scattered in the interfollicular areas and did not resemble plasma cells. Spontaneous IL-6 production was detected in the culture supernatants of peripheral blood mononuclear cells (PBMNC) from four patients. The IL-6 producing cells among the PBMNC were found to be monocytes by both in situ hybridization and immunohistochemistry. We evaluated immune function in four MCD patients. These studies show: (1) a negative PPD skin test in 3/4 patients. (2) decreased IL-2 production in 3/4 patients, (3) decreased T cell colony formation in 3/4 patients, (4) decreased NK activity and NK cell number in 2/4 patients, (5) increased soluble IL-2 receptor in 4/4 patients, and (6) decreased CD4/CD8 ratio in 3/4 patients. These results show that MCD resembles, in several ways, acquired immunodeficiency syndrome (AIDS). 相似文献
996.
997.
To evaluate the attenuation of the effectiveness of long-term ibopamine therapy, ibopamine was administered in single doses of 100 and 200 mg to 10 patients with chronic heart disease. The hemodynamic studies using Swan-Ganz catheter and pharmacokinetic studies were carried out. Ibopamine was found to increase cardiac output and stroke index and to decrease systemic vascular resistance in this acute study. Six patients underwent long-term therapy with the drug and were evaluated for the development of tolerance. Three out of 5 patients experienced an improvement in NYHA functional class after 12-23 weeks of treatment. There was no attenuation in the effects of ibopamine on hemodynamics, pharmacokinetic parameters remained almost unchanged, and tolerance was not observed. These results suggest that ibopamine is useful as an orally administered anti-heart failure drug. 相似文献
998.
Successful resection of a glomus tumor arising from the lower trachea: Report of a case 总被引:1,自引:0,他引:1
Masazumi Watanabe Keigo Takagi Katsuaki Ono Teruhiro Aoki Susumu Tanaka Hideyuki Shimazaki Shinsuke Aida 《Surgery today》1998,28(3):332-334
(Received for publication on Sept. 30, 1996; accepted on Mar. 4, 1997) 相似文献
999.
K Koike T Hanada I Ono Y Nagai K Shin N Mori H Takita 《[Rinshō ketsueki] The Japanese journal of clinical hematology》1989,30(11):2008-2013
A 4-year-old girl was admitted because of fever, swelling of left chest wall and left axillary lymphadenopathy. Chest XP revealed left pleural effusion. Ga-scintigram showed multiple accumulation in skull, left ribs and iliac bone. A diagnosis of childhood Ki-1 lymphoma was made from the pathological findings of tumor in the skull. Immunopathological study revealed that the neoplastic cells were CD8 positive (suppressor phenotype). 相似文献
1000.
Yukiko Hayashi Masashi Fukayama Yumiko Shiozawa Morio Koike 《Pathology international》1989,39(11):737-742
In order to demonstrate the ultrastructural localization of the α subunit of human chorionic gonadotropin (hCG) in the stomach mucosa, an immunoelectron microscopic study was performed using formalin-fixed specimens. In pyloric glands, α hCG-positive granules were irregular in outline, with a mean area and maximum diameter of 2.857 × 104 nm2 and 218.4 nm, respectively. In fundic glands, the granules had a smoother outline and were larger in both area and maximum diameter (3.943 × 104 nm2 , 246.8 nm) than those of pyloric glands (p <0.001). In the atrophic fundic glands of non antral gastritis, the αhCG granules showed a differece in shape; more elliptical granules appeared to be increased, as indicated by the higher value of the axial ratio (1.452) and lower value of D (1.862) (log10 area ∞ D log10 perimeter) compared with those in pyloric (1.231, 1.968) and fundic glands (1.148, 1.979) (p< 0.001). The a-subunit of hCG is thus Incorporated into different types of endocrine cell in pyloric and fundic glands, and the granule morphology appears to differ in hyperplastic αhCG cells of non-antral gastritis. Acta Pathol Jpn 39: 737-742, 1989. 相似文献