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61.
Kanaji Taisuke; Okamura Takashi; Osaki Koichi; Kuroiwa Mika; Shimoda Kazuya; Hamasaki Naotaka; Niho Yoshiyuki 《Blood》1998,91(6):2010-2014
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64.
Terufumi Kawamoto Tsunekazu Hishima Kiminori Kimura 《Clinical journal of gastroenterology》2014,7(5):460-464
Neuroendocrine tumors consist of a spectrum of malignancies that arise from neuroendocrine cells throughout the body. Pancreatic neuroendocrine tumors are rare tumors, with an incidence of 3.65 per 100,000 individuals per year, and they account for 1–2 % of all pancreatic neoplasms. A non-functioning pancreatic neuroendocrine tumor with multiple liver metastases with calcifications was diagnosed in a 43-year-old female with diabetes mellitus. Early phase-enhanced computed tomography (CT) showed a hypovascular mass in the pancreatic body and tail with calcifications and multiple liver metastatic masses with calcifications. Percutaneous liver biopsy showed homogenous nuclear chromatins and tumor cells with acidophilic cytoplasm against the hyaline interstitium, and a non-functioning pancreatic neuroendocrine tumor was diagnosed. An interesting clinical image of a metastasis from a pancreatic neuroendocrine tumor is presented in which multiple liver tumors were accompanied by dystrophic calcifications. CT and percutaneous liver biopsy play an important role in the diagnosis of a non-functioning pancreatic neuroendocrine tumor, and are valuable diagnostic methods in planning treatment. 相似文献
65.
Shivathirthan N Shimoda M Kosuge T Kato M Kijima H Sawada T Kubota K 《Hepato-gastroenterology》2012,59(115):872-874
For resection of advanced hepatocellular carcinoma (HCC) in which tumor thrombus (TT) extends into inferior vena cava (IVC) or right atrium (RA) surgery is challenging and requires skillful techniques. Here, we report a case of recurrent HCC with TT extending to the RA, who underwent successful resection with tumor thrombectomy without concomitant cardiopulmonary bypass. A 71-year-old man, who had been followed- up for hepatitis C by a local hospital, was diagnosed as having HCC in segment 6 for which he had undergone segmentectomy of segment 6 in May 2009. During follow-up, he developed severe leg edema and ascites with investigations revealing recurrent HCC in segment 7 with TT extending to the right atrium via IVC. After transarterial embolization the patient underwent extended resection of the segment 7 with tumor thrombectomy of the IVC and the right atrium and partial resection of the IVC wall using total hepatic vascular exclusion, without concomitant cardiopulmonary bypass. Total ischemic time was 23 minutes, operation time was 6 hours and blood loss was 2,474mL. The postoperative course was uneventful. Histopathology was recurrent hepatocellular carcinoma with hepatic venous invasion. We report the case of resected recurrent HCC with TT extending to right atrium without concomitant cardiopulmonary bypass. 相似文献
66.
During mental rotation tasks using hand pictures, right-handers make left–right judgements by mentally rotating their own hand to an orientation of the presented hand image. Although strategy difference for the tasks between left- and right-handers has been suggested, the strategy of left-handers has been incompletely understood. In the present study we compared differences in reaction times between 15 left-handed and 16 right-handed normal individuals during a mental rotation task using simple hand pictures. Participants were required to identify pictures of a hand presented in four orientations (upright, counterclockwise rotated, clockwise rotated, and inverted) as either a right or a left hand. Right-handers recognised a right hand faster than a left hand, whereas no significant difference was seen for left-handers. Both left- and right-handers recognised a right hand faster than a left hand in counterclockwise-rotated images, and recognised a left hand faster than a right hand in clockwise-rotated images. The findings suggest that the differences in the reaction times between left- and right-handers depend on a laterality balance of hand motor skills. During mental rotation task using simple hand pictures, left-handers may mentally simulate their own hand to match the stimulus image as similar to right-handers. 相似文献
67.
Yoshimi Iwasaki Mitsuru Ishizuka Masato Kato Junji Kita Mitsugi Shimoda Keiichi Kubota 《World journal of surgery》2013,37(9):2222-2228
Background
An inflammation-based prognostic score, the modified Glasgow Prognostic Score (mGPS), has been established as a useful tool for predicting postoperative outcome in patients with cancer. However, no studies have investigated the usefulness of the mGPS for prognostication in patients undergoing palliative surgery for unresectable malignant biliary obstruction (UMBO). The present study was conducted to investigate whether the mGPS is useful for predicting the postoperative survival of patients undergoing intraoperative placement of an expandable metal stent for UMBO, or not.Methods
The mGPS was calculated as follows: patients with both an elevated level of C-reactive protein (CRP) (>1.0 mg/dL) and hypoalbuminemia (<3.5 g/dL) were allocated a score of 2. Patients with only an elevated CRP level were allocated a score of 1, and patients without an elevated CRP level (≤1.0 mg/dL) were allocated a score of 0. Postoperative survival was evaluated by Kaplan–Meier analysis and log rank test. The significance of risk factors for postoperative survival was evaluated with the Cox proportional hazards model.Results
Kaplan–Meier analysis revealed that patients with mGPS 0 (n = 36) and 1 (n = 7) had better postoperative survival (p = 0.017) than patients with mGPS 2 (n = 17). The 6-month and 1-year survival rates of patients with mGPS 0 and 1 were 58.1 and 27.3 %, and those for patients with mGPS 2 were 25.0 and 6.2 %, respectively. Multivariate analysis revealed that mGPS (0, 1/2) was a significant risk factor for postoperative survival (hazard ratio 3.271; 95 % CI 1.109–9.649; p = 0.032).Conclusion
The mGPS is not only one of the most significant predictors of postoperative survival for UMBO patients receiving intraoperative biliary stenting but also a useful indicator capable of dividing such patients into two independent groups before surgery. 相似文献68.
69.
Toshio Kaneda Toshihiko Saga Masahiko Onoe Hitoshi Kitayama Susumu Nakamoto Terufumi Matsumoto 《Scandinavian cardiovascular journal : SCJ》2013,47(1-2):87-90
Objective Antegrade selective cerebral perfusion (ASCP) and retrograde cerebral perfusion (RCP) have proven to be reliable methods of brain protection during aortic surgery. These techniques are usually accompanied by systemic circulatory arrest with moderate hypothermia (24–28°C) or deep hypothermia (18–24°C). However, hypothermia can lead to various problems. The present study therefore reports results for thoracic aorta replacement using ASCP with mild hypothermic systemic arrest (28–32°C). Design Between 1995 and 2003, 68 consecutive patients underwent repair of the ascending aorta and/or aortic arch. Mild hypothermic ASCP was utilized in 31 cases, moderate hypothermic ASCP in 20, and deep hypothermic RCP in 17. Various parameters were compared between the mild hypothermic ASCP, moderate hypothermic ASCP, and RCP. Results Hospital mortality was 10.3%, with no significant differences observed between any groups. Permanent neurological dysfunction was 8.8%, and no significant differences were observed between any groups. Mild hypothermic ASCP displayed significantly decreased transfusion volume, intubation time, and ICU stay. Conclusions Use of ASCP with mild hypothermic systemic circulatory arrest during aortic surgery resulted in acceptable hospital mortality and neurological outcomes. ASCP with mild hypothermic arrest allows decreased transfusion volume and reduced duration of intubation and ICU stay. 相似文献
70.
Risk Factors for Early Recurrence of Single Lesion Hepatocellular Carcinoma After Curative Resection
Mitsugi Shimoda Kazuma Tago Takayuki Shiraki Shozo Mori Masato Kato Taku Aoki Keiichi Kubota 《World journal of surgery》2016,40(10):2466-2471