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11.
背景:挽救缺血半暗带对减少梗死范围有重要意义,一般以PWI与DWI的不匹配区域来评估半暗带.但PWI评估的低灌注范围可能会包括良性缺血区,从而使评估所得的半暗带体积大于实际值.为减少这种弊端,近来引入一新的参数:PWI的达峰时间(Tmax)阈值.Tmax为PWI成像信号强度-时间曲线中从对比剂开始出现到对比剂浓度达到峰值的时间.以对侧相应部位正常脑组织的Tmax为参考,脑组织中Tmax延迟超过阈值的区域即为PWI病灶区. 相似文献
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Leonard C Pastrav Siegfried VN Jaecques Ilse Jonkers Van der Georges Perre Michiel Mulier 《Journal of orthopaedic surgery and research》2009,4(1):10
Background
The per-operative assessment of primary stem stability may help to improve the performance of total hip replacement. Vibration analysis methods have been successfully used to assess dental implant stability, to monitor fracture healing and to measure bone mechanical properties. The objective of the present study was to evaluate in vivo a vibration analysis-based endpoint criterion for the insertion of the stem by successive surgeon-controlled hammer blows. 相似文献13.
A survey on clinical presentation and nutritional status of infants with suspected cow' milk allergy
Mário C Vieira Mauro B Morais José VN Spolidoro Mauro S Toporovski Ary L Cardoso Gabriela TB Araujo Victor Nudelman Marcelo CM Fonseca 《BMC pediatrics》2010,10(1):25
Background
Cow's milk is the most common food allergen in infants and the diagnosis of cow's milk allergy is difficult, even with the use of several diagnostic tests. Therefore, elimination diets and challenge tests are essential for the diagnosis and treatment of this disorder. The aim of this study is to report the clinical presentation and nutritional status of children evaluated by pediatric gastroenterologists for the assessment of symptoms suggestive of cow's milk allergy. 相似文献14.
K Sardana VK Garg VN Sehgal S Mahajan P Bhushan 《Journal of the European Academy of Dermatology and Venereology》2009,23(5):556-560
Background In view of the potentially serious side-effects of standard isotretinoin (0.5–1.0 mg/kg per day) therapy for acne, we studied the safety and efficacy of low-fixed dose isotretinoin plus topical 1%clindamycin gel in the treatment of moderate grade of acne.
Methods In this prospective, non-comparative study, 320 adult patients, with moderately severe acne were enrolled and treated with fixed-dose isotretinoin at 20 mg every alternate day (approximately 0.15 mg/kg/day to 0.28 mg/kg/day) for 6 months along with topical clindamycin gel. All female patients were assessed for polycystic ovarian disease. Patients were followed up for 6 months.
Results A total of 305 patients completed the study. Overall, patients received a mean of 38.4 mg/kg cumulative dose of isotretinoin, and very good results were observed in 208 (68.20%), while good response was seen in 59 (19.34%) of patients. Failure of the treatment occurred in 38 (12.46%), while relapses occurred in 50 (16.39%) of patients. Relapses were commoner in females, and 37 of 43 (86.04%) patients had polycystic ovarian disease. Though mild chelitis (91%) and xerosis (43%) were common, laboratory abnormalities in the form of elevated hepatic enzymes (5%) and elevated serum lipids (6%) were rare.
Conclusion Six months of treatment with fixed-dose, alternate-day isotretinoin (20 mg) plus topical 1%clindamycin gel was found to be effective in the treatment of moderate acne in adult patients, with a low incidence of side-effects.
None declared 相似文献
Methods In this prospective, non-comparative study, 320 adult patients, with moderately severe acne were enrolled and treated with fixed-dose isotretinoin at 20 mg every alternate day (approximately 0.15 mg/kg/day to 0.28 mg/kg/day) for 6 months along with topical clindamycin gel. All female patients were assessed for polycystic ovarian disease. Patients were followed up for 6 months.
Results A total of 305 patients completed the study. Overall, patients received a mean of 38.4 mg/kg cumulative dose of isotretinoin, and very good results were observed in 208 (68.20%), while good response was seen in 59 (19.34%) of patients. Failure of the treatment occurred in 38 (12.46%), while relapses occurred in 50 (16.39%) of patients. Relapses were commoner in females, and 37 of 43 (86.04%) patients had polycystic ovarian disease. Though mild chelitis (91%) and xerosis (43%) were common, laboratory abnormalities in the form of elevated hepatic enzymes (5%) and elevated serum lipids (6%) were rare.
Conclusion Six months of treatment with fixed-dose, alternate-day isotretinoin (20 mg) plus topical 1%clindamycin gel was found to be effective in the treatment of moderate acne in adult patients, with a low incidence of side-effects.
Conflicts of interest
None declared 相似文献
15.
TS Papavramidis S Potsi D Paramythiotis A Michalopoulos VN Papadopoulos V Douros A Pantoleon A Foutzila-Kalogera I Ekonomou N Harlaftis 《Journal of Korean medical science》2009,24(6):1216-1219
The present case is one of gallstone obstructive ileus due to gallstones 3 yr after laparoscopic cholecystectomy. It is interesting because of the sex of the patient, the fact that ileus occurred 3 yr after cholecystectomy and that the localization of the obstruction was an old side-to-side ileoileal anastomosis due to a diverticulectomy following intussusception of Meckels'' diverticulum at the age of 3. 相似文献
16.
VN Sehgal R Kak A Aggarwal G Srivastava P Rajput 《Journal of the European Academy of Dermatology and Venereology》2007,21(4):473-479
BACKGROUND: Androgenetic alopecia (AGA) has received scant attention, despite it being a common entity that may result in significant psychosocial morbidity. There are some patients who do not fit into any of the proposed types. Moreover, there have been no published studies of pattern and prevalence of AGA in males in an Indian context. Hence, the present study was an attempt to classify AGA in males with the aim of producing a simple, effective and easily reproducible classification. METHODS: In total, 150 male patients were clinically diagnosed as AGA. After obtaining informed consent from all patients, a detailed history/examination was carried out, including a hair pull test, a trichogram investigation and a biopsy. Classification of AGA was subsequently attempted across Norwood guidelines. RESULTS: A gradual shift in the type of AGA from the earlier types (II and III) to more severe types (VI) with increasing age was significant. Twenty-seven patients did not fit into specific patterns according to Hamilton and Norwood classifications. In addition, type 'a' variant was recorded in 20% of patients, clearly indicating limitations of the existing classifications. CONCLUSIONS: It was possible to classify 80% of the AGA, with II (28%) and III (15%) being the most common types of AGA. Twenty-seven patients (18%) could not be classified as a significant finding. There was considerable overlap in types IV, V and VI in the Norwood classification with the 'a' variants further confusing the picture. 相似文献
17.
The distribution of three integrin subunits, alpha3, alpha5 and alpha(v),
in immature and mature human oocytes has been examined using
immunofluorescence and confocal microscopy. The results demonstrate that
both alpha5 and alpha(v) are present at the germinal vesicle stage, while
alpha3 was only detected in oocytes after germinal vesicle breakdown, in
metaphase I and II stage oocytes. The cortical concentration of integrin
subunits alpha3 and alpha5 is consistent with their localization in the
oolemma. In contrast, the homogeneous distribution of alpha(v) throughout
the oocyte suggests the existence of cytoplasmic reservoirs of this protein
in the oocyte.
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