胫后神经体感诱发电位对脊髓病变的定位诊断

目的：研究胫后神经体感诱发电位（ＳＥＰ）对脊髓病变的定位诊断价值。方法：电刺激胫后神经，于腰椎、胸椎、颈椎和头皮置记录电极，依次记录ＣＥ，Ｎ２４，Ｎ２８和Ｐ４０电位峰潜伏期。共检测１５例对照组和２９例经磁共振（ＭＲＩ）证实的腰骶神经根或脊髓病变患者。结果：（１）ＣＥ，Ｎ２４，Ｎ２８和Ｐ４０电位均异常，见于腰骶神经根病变。（２）ＣＥ正常，Ｎ２４，Ｎ２８和Ｐ４０异常，或Ｎ２４异常，余电位均正常，见于腰骶髓病变。（３）ＣＥ，Ｎ２４正常，Ｎ２８和Ｐ４０异常，见于胸髓病变。（４）ＣＥ，Ｎ２４，Ｎ２８正常，Ｐ４０异常，见于第６颈椎以上病变。结论：胫后神经ＳＥＰ临床上具有定位诊断价值     

Association of hepatitis B and human immunodeficiency virus infections in Tanzanian population groups

A study was performed to determine whether there is a correlation between hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection in population groups in the Dar es Salaam area in Tanzania where HBV infection is endemic. A panel of 460 sera from army recruits, health personnel and pregnant women was tested. In the whole group seromarkers of HBV infection were found in 61.9 % of 134 HIV positive subjects versus 51.5 % of 326 seronegative subjects, a difference which was not statistically significant (p>0.05). In the group of pregnant women, however, 66.7 % of 120 HIV positive subjects had markers of HBV infection versus 49.0 % of the 157 HIV seronegative subjects (p<0.01). This shows that a considerable proportion of young females are also exposed to HBV at the time they acquire HIV infection.     

蚯蚓提取物治疗慢性肾小球肾炎的研究

对２６例慢性肾小球肾炎患者观察了口服蚯蚓提取物治疗前后血压、血尿素氮及血浆内皮素的变化。结果显示，蚯蚓提取物治疗２周后血压、血尿素氮及血浆内皮素均明显下降，提示蚯蚓提取物治疗能改善肾功能。其疗效的机理可能与蛆蚓提取物治疗能使血浆内皮素的含量下降有关。     

瓜蒌皮抗缺氧作用的研究

实验结果显示，瓜蒌皮提取液（ＥＰＴ）腹腔注射４０ ｇ·ｋｇ－１能明显延长常压缺氧、组织缺氧、特异性心肌缺氧小鼠的存活时间，延长率分别为 １４５％， ２．７９％， １１０．７％，使减压缺氧小鼠的存活率达８５％．表明瓜蒌皮确能增强整体动物的抗缺氧能力．     

93例儿童血脂谱水平与ApoB基因多态性关系的研究

目的观察儿童血脂谱水平与载脂蛋白Ｂ（ＡｐｏＢ）基因变异的关系。方法对９３名８～１１岁汉族儿童进行了ＡｐｏＢ基因ＸｂａⅠ位点多态性基因型频率及基因型与血脂谱水平关系的研究。结果此人群中ＸｂａⅠ位点优势等位基因Ｘ－频率为０．９６７，少见等位基因Ｘ＋频率为０．０３３；Ｘ－Ｘ＋基因型者（此人群中无Ｘ＋Ｘ＋者）血浆总胆固醇、低密度脂蛋白－胆固醇（ＬＤＬ－ｃｈ）水平均值（４．５９和２．９８ｍｍｏｌ／Ｌ）显著高于Ｘ－Ｘ－基因型者（３．８４和２．３２ｍｍｏｌ／Ｌ），全部６例Ｘ－Ｘ＋者中的４例，其总胆固醇和／或ＬＤＬ－ｃｈ测定值分别超过了Ｐ９０，显示了Ｘ＋等位基因与高血浆胆固醇水平的联系。结论ＡｐｏＢ基因ＸｂａⅠ位点多态性与儿童血脂谱水平有一定程度的关联，有可能是儿童血脂谱水平异常的遗传标志之一。     

1995—1997年青岛口岸急性腹泻病监测报告

应用流行病学方法，自1995年1月至1997年12月，连续三年对青岛口岸487例急性腹泻病患者的资料进行了病原学分析。病原菌检出率为56．06％，其中以痢疾杆菌、志贺氏菌和致病性大肠杆菌为主，占81．32％；发病年龄以40岁以下患者为主，为88．09％，而且病原菌检出率也较高，占61．77％；发病季节以6～9月为最多，共358例，占73．51％，病原菌检出率为60．61％；患者的性别无差异。病因以食源性为多见，占62．22％。     

两种不同心脏移植手术的对比研究

采用单纯主动脉吻合于腹主动脉的心肺联合移植手术和双血管即主动脉和肺动脉分别吻合于腹主动脉和下腔静脉的心脏移植手术，从手术后12h成活率，术后12~72h成活率以及术后清理改变等方面进行比较分析，我们认为在作心脏移植排斥反应模型时应用双血管吻合的心脏移植方法较好。     

磷脂复合物对大鼠延缓衰老的作用

本文报告了磷脂复合物对９月龄ＳＤ大鼠血红细胞ＳＯＤ活力，心肌丙二醛（ＭＤＡ）含量及尾动脉容积脉搏图的影响，试验表明，基础饲料添加１０％磷脂复合物原粉或稀释粉均能使血红细胞ＳＯＤ活力显著增加，（Ｐ＜０．０１，Ｐ＜０．０５）。其中高剂量组心肌丙二醛含量显著降低（Ｐ＜０．０５），且容积脉搏图中降中峡相对深度显著增加（Ｐ＜０．０５）。结果提示，磷脂复合物有增加血红细胞ＳＯＤ活力，降低脂质过氧化和减少尾动脉外周阻力的作用。     

盐酸戊乙奎宁在水溶液中的降解机理

Penequine hydrochloride (Ⅰ) is a new potent anticholinergic drug, the degradation mechanism of Ⅰ in aqueous solutions is reported in this paper. Ⅰ is an ethereal compound, stable in neutral and alkaline solutions, but it decomposes in strong acidic solutions. Its main degradation products have been separated and identified by means of TLC, MS, GC/MS and GC/FTIR. With reference to the general degradation rule of ethereal compound and the structure of the degradation products, we deduced that the ether linkage of Ⅰ splits in acidic solutions by the catalysis of hydrogen ion, producing 3- quinuclidinol (DP1) and 1-phenyl- 1-cyclopentyl glycol. The latter turns into 1-phenyl-l-cyclopentyl acetaldehyde through dehydration and rearrangement. In addition, small amounts of other degradation compounds, e. g. benzaldehyde, acetophenone, phenylcyclopentyl ketone, etc. have also been found, but the mechanism remains to be further studied.