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31.
Iraj Salehi Shabnam Khazaeli Parta Hatami Mahdi Malekpour 《Rheumatology international》2010,30(8):1137-1138
Chondromalacia of the patella is the most common cause of anterior knee pain in young women. The etiology of the disease is
not well-understood but the initial lesion is a disorganization of collagenous structures. Since the disease is proposed to
be due to generalized constitutional disturbance, we postulated that bony structures could also be involved. To investigate
this hypothesis we measured the bone density of 286 patients with the diagnosis of chondromalacia of the patella during a
4-year period using dual energy X-ray absorptiometry (DXA) method. We found a significant number of patients having low bone
densities. This problem was more pronounced in men and in younger age groups. We suggest base-line bone density evaluation
in all patients, treatment of osteopenia or osteoporosis in select patients and regular follow-ups using DXA. 相似文献
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Ultrasound‐guided wire localization of focal ductal dilatation in the evaluation and treatment of pathologic nipple discharge 下载免费PDF全文
Anya Romanoff MD Benjamin Nulsen MD Jolinda Mester MD Shabnam Jaffer MD Christina Weltz MD 《The breast journal》2018,24(3):356-359
Patients presenting with pathologic nipple discharge (PND) often pose a diagnostic and therapeutic challenge. We used ultrasound to identify focal ductal dilatation—hypothesized to be a radiographic manifestation of the causative lesion—in patients with PND and no relevant clinical or radiographic findings. Twenty‐two excisions guided by ultrasound wire localization of focal duct dilation were performed. Surgical pathology revealed papilloma in 20 cases (91%); atypia or carcinoma was detected in 7 cases (32%). The ultrasound finding of focal duct dilatation enables excision of otherwise occult though clinically significant lesions and is worthy of further study. 相似文献
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Noori ZT Fekrazad R Eslami B Etemadi A Khosravi S Mir M 《Lasers in medical science》2008,23(3):283-287
There are several studies done to show the comparability of laser scaling and root planing with routine methods. The most suitable wavelengths for such an application are reported as 2,940 and 2,780 nm. The superficial interactions of the current wavelength with root surface is investigated in this study to compare the crater and crack formation during the procedures between ultrasound and Er,Cr:yttrium-scandium-gallium garnet (YSGG; 2,780 nm) laser-treated teeth. Thirty human teeth with calculus on their root surface, which were extracted because of the severe periodontitis, were selected for this interventional in vitro study. Calculus area were divided into two equal parts: One of them was prepared for Er,Cr:YSGG (Biolase, Waterlase, USA) laser irradiation and the other one for ultrasound treatment (Dentsply cavitron, DENTSPLY International, USA). The Er,Cr:YSGG laser was specified as follows: pulse energy = 50 mJ, power = 1 W, wavelength = 2,780 nm, pulse repetition rate = 20 pulse per seconds, tip length = 6 mm, and tip diameter = 600 microm. Nineteen of the laser samples (95%) and eight of ultrasound ones (40%) out of 20 samples in each group had craters showing a statistical significant difference (p < 0.001). The number and depth of these craters are also evaluated. Thirteen samples of the laser cases (65%) and all samples of the ultrasound group showed cracks with significant differences (p = 0.008). In addition, the number and width of cracks in both groups are reported. As a general conclusion, the laser-treated samples show more craters but less cracks. 相似文献
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Shabnam Babataheri Hassan Malekinejad Arash Mosarrezaii Hamid Soraya 《Fundamental & clinical pharmacology》2023,37(3):589-598
Stroke is a serious life-threatening medical condition and is one of the principal reasons for death and disabilities worldwide. The aim of the present study was to determine the neuroprotective effects of hydroxychloroquine (HCQ) and the timing of its administration in cerebral ischemia/reperfusion (I/R) in rats. A global I/R model was used, and HCQ was administered in either pre- or post-treatment doses of 25 and 50 mg/kg. Effects of HCQ on infarct size, histological changes, oxidative stress, and learning and memory were evaluated. Phospho-AMPK and SQSTM1/p62 protein levels were also measured to elucidate the possible mechanisms involved. HCQ in both pre- (at doses of 25 and 50 mg/kg) or post-treatment (at a dose of 50 mg/kg) protocols reduces brain infarct size and histopathological changes and improves learning and memory after cerebral I/R. Pre-treatment with HCQ reduced AMPK activity with no significant effect on SQSTM1/p62 increment. Post-treatment with HCQ increased AMPK activity and SQSTM1/p62 protein levels. Our results show the neuroprotective effects of HCQ on cerebral I/R through the reduction in infarct size, histopathological changes, and improvement in memory and learning functions. Moreover, AMPK and autophagy may play a role in this protective effect. 相似文献
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