全文获取类型
收费全文 | 12766篇 |
免费 | 640篇 |
国内免费 | 112篇 |
专业分类
耳鼻咽喉 | 313篇 |
儿科学 | 652篇 |
妇产科学 | 530篇 |
基础医学 | 923篇 |
口腔科学 | 420篇 |
临床医学 | 1021篇 |
内科学 | 3261篇 |
皮肤病学 | 192篇 |
神经病学 | 752篇 |
特种医学 | 544篇 |
外科学 | 3037篇 |
综合类 | 172篇 |
一般理论 | 1篇 |
预防医学 | 293篇 |
眼科学 | 456篇 |
药学 | 460篇 |
中国医学 | 23篇 |
肿瘤学 | 468篇 |
出版年
2024年 | 11篇 |
2023年 | 111篇 |
2022年 | 208篇 |
2021年 | 392篇 |
2020年 | 247篇 |
2019年 | 305篇 |
2018年 | 385篇 |
2017年 | 307篇 |
2016年 | 524篇 |
2015年 | 600篇 |
2014年 | 654篇 |
2013年 | 788篇 |
2012年 | 1036篇 |
2011年 | 935篇 |
2010年 | 575篇 |
2009年 | 491篇 |
2008年 | 848篇 |
2007年 | 994篇 |
2006年 | 912篇 |
2005年 | 895篇 |
2004年 | 797篇 |
2003年 | 596篇 |
2002年 | 538篇 |
2001年 | 67篇 |
2000年 | 36篇 |
1999年 | 48篇 |
1998年 | 57篇 |
1997年 | 41篇 |
1996年 | 29篇 |
1995年 | 24篇 |
1994年 | 15篇 |
1993年 | 7篇 |
1992年 | 8篇 |
1991年 | 10篇 |
1990年 | 9篇 |
1989年 | 4篇 |
1988年 | 2篇 |
1986年 | 2篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1975年 | 1篇 |
1973年 | 2篇 |
排序方式: 共有10000条查询结果,搜索用时 19 毫秒
991.
Demir E Irobi J Erdem S Demirci M Tan E Timmerman V De Jonghe P Topaloglu H 《Journal of child neurology》2003,18(1):76-79
Agenesis of the corpus callosum with peripheral neuropathy or Andermann syndrome is an autosomal recessive disorder rarely found outside certain regions of the province of Quebec, Canada. We report a 5-year-old Turkish patient with Andermann syndrome born to consanguineous parents. She presented with diffuse hypotonic weakness, predominantly in the distal extremities, and mild mental retardation. Electromyography showed axonal-demyelinating sensorimotor neuropathy. Sural nerve biopsy was compatible with demyelinating neuropathy. Cranial magnetic resonance imaging revealed total agenesis of the corpus callosum, dilatation of the interhemispheric fissure, and enlargement of the cisterna magna. The molecular genetic analysis using microsatellite DNA markers covering the agenesis of the corpus callosum with peripheral neuropathy locus on chromosome 15q13-q15 showed that the patient is homozygous for the whole region. Our findings confirm that Andermann syndrome is a genetically homogeneous disorder. 相似文献
992.
Interest in complementary-alternative medicine therapies is growing rapidly in Turkey. Therefore, the purpose of this research was to determine the types and prevalence of alternative therapies used by the patients with a diagnosis of cancer, and to determine factors influencing the choices of their therapies in Erzurum, Turkey. Approximately 10-minute face-to-face interviews were conducted with each subject in the radiation oncology department. The factors associated with the use of alternative therapies after a diagnosis of cancer were assessed by chi-square analysis. The findings indicated that complementary-alternative medicine therapies were used by 41.1% of the subjects after their diagnosis, and that all of the alternatives they used were herbs. The most commonly used herb was stinging nettle leaf (urtica dioica) or seed of nettle. Almost all (93.2%) of the herbs used were nettle. In general, especially the women and the younger patients of both genders were more likely to be using alternative therapies. There was no difference in demographic and cancer characteristics between users of alternative therapy and nonusers. More than the half of the patients using alternative therapies (54.5%) reportedly did not discuss the use of herbs with their healthcare professionals. Most of the patients using stinging nettle and other herbs therapies reported that they had heard about the use of herbs from friends or relatives (52.3%), or from the other patients in this clinic (43.2%). This study found that there is a high prevalence of alternative therapies used by patients with cancer in eastern Turkey. The use of these alternative therapies requires that nursing professionals rethink staff competency, patient assessment, and patient-focused care. Communication between patients and healthcare professionals should initiate dialogues on this topic for a better understanding of patient choices with regard to treatment options. 相似文献
993.
Bakan N Taysi S Yilmaz O Bakan E Kuşkay S Uzun N Gündoğdu M 《Clinica chimica acta; international journal of clinical chemistry》2003,338(1-2):143-149
BACKGROUND: Chronic lymphocytic leukemia (CLL) is a rare neoplasm that comprises a substantial proportion of all leukemias in middle-aged persons and is the most common type among elderly persons. The major causes are not known nor is there a detailed understanding about how the elusive origin(s) may relate to clinical expression, basic biological mechanisms, or pathogenesis. METHODS: Glutathione peroxidase (GSH-Px), glutathione reductase (GRD), Cu-Zn superoxide dismutase (Cu-Zn SOD) activities, glutathione (GSH), nitric oxide (NO(*), and malondialdehyde (MDA) concentrations were measured in serum of patients with CLL and a healthy control group. RESULTS: Serum GSH-Px, Cu-Zn SOD activities, GSH concentration were lower in patients with CLL while serum NO(*) and MDA concentrations were higher in these patients compared with the control group. Serum GRD activity was not statistically significant in patients with CLL compared with the control. However, there was no statistically significant difference in the parameters on the basis of stages in these patients. Serum GSH concentration negatively correlated with serum MDA (r=30.63, p<0.05) and NO(*) concentrations (r=0.72, p<0.05) in patients with advanced stage (III+IV). However, no other correlation could be found among the parameters in healthy controls and patients with CLL CONCLUSIONS: There is significant changes in antioxidant defense system in CLL cases, which may lead to enhanced action of oxygen radical, resulting in lipid peroxidation. 相似文献
994.
Paranasal sinus osteoma is a slow-growing, benign, encapsulated bony tumour that may be commonly asymptomatic, being detected incidentally in 1% of plain sinus radiographs or in 3% sinus computerized tomographic scans. In a patient presenting with epiphora and nasal obstruction, computed tomography disclosed a giant osteoma of the ethmoid. In this article, one patient having giant ethmoidal osteoma with orbital extension is described, and epidemiology, diagnosis, treatment, and pathological findings in paranasal sinus osteoma are reviewed. 相似文献
995.
Treatment of humeral shaft non-unions by the Ilizarov method 总被引:4,自引:1,他引:3
Thirty-five humeral shaft non-unions treated by the Ilizarov external fixator were studied after an average of 39 months. Bone union was achieved in all but one. The mean time to union was 5.5 months (range: 3-10 months). Major pin tract problems leading to removal of the Schanz screws occurred in three patients. A radial nerve palsy developed in three patients, two recovered spontaneously and one was treated with a triple tendon transfer. 相似文献
996.
Erdoğan O Bülbül M Demircin G Oner A Memiş L 《Pediatric nephrology (Berlin, Germany)》2001,16(3):265-268
To date, all the reported cases of acute necrotizing tubulointerstitial nephritis (TIN) secondary to systemic adenovirus infection
have occurred in individuals with primary or secondary immunodeficiency, and have resulted in renal failure and death. We
present the case of a 12-year-old, immunologically competent girl who developed acute necrotizing TIN with acute renal failure
(ARF), hepatitis and meningoencephalitis secondary to a systemic adenoviral infection who completely recovered with supportive
care.
Received: 11 February 2000 / Revised: 6 July 2000 / Accepted: 18 August 2000 相似文献
997.
Aysegul Yildirim Fevzi Akinci Hulya Gozu Haluk Sargin Ekrem Orbay Mehmet Sargin 《Quality of life research》2007,16(5):873-879
Objective The aim of this study was to test the validity and reliability of the Turkish version of the diabetes quality of life (DQOL)
questionnaire for use with patients with diabetes. Methods Turkish version of the generic quality of life (QoL) scale 15D and DQOL, socio-demographics and clinical parameter characteristics
were administered to 150 patients with type 2 diabetes. Study participants were randomly sampled from the Endocrinology and
Diabetes Outpatient Department of Dr. Lutfi Kirdar Kartal Education and Research Hospital in Istanbul, Turkey. Results The Cronbach alpha coefficient of the overall DQOL scale was 0.89; the Cronbach alpha coefficient ranged from 0.80 to 0.94
for subscales. Distress, discomfort and its symptoms, depression, mobility, usual activities, and vitality on the 15 D scale
had statistically significant correlations with social/vocational worry and diabetes-related worry on the DQOL scale indicating
good convergent validity. Factor analysis identified four subscales: satisfaction”, impact”, “diabetes-related worry”, and
“social/vocational worry”. Conclusion Statistical analyses showed that the Turkish version of the DQOL is a valid and reliable instrument to measure disease related
QoL in patients with diabetes. It is a simple and quick screening tool with about 15 ± 5.8 min administration time for measuring
QoL in this population. 相似文献
998.
Arif Kokcu Mehmet B Cetinkaya Oguz Aydin Migraci Tosun 《The journal of maternal-fetal & neonatal medicine》2007,20(4):349-356
In this article we review the historically important cases of conjoined twins (Biddenden Maids, Siamese twins, Blazek sisters) and contemporary knowledge regarding incidence, etiopathogenesis, antenatal diagnosis, antenatal management, and outcome of conjoined twins. We also present a case of male cephalothoracoomphalopagus, which is extremely rare. 相似文献
999.
Ibrahim Tuncer Sinan Bilgin Mehmet
zgür Zengin Mehmet Serhat Mangan Abdullah Karaca Cezmi Doan Esat nar 《Eye (London, England)》2021,35(2):672
BackgroundTo evaluate the effect of brimonidine tartrate 0.15% ophthalmic solution on pupil size under scotopic condition and upper eyelid position.MethodsThis study comprised 72 eyes of 36 healthy subjects. A single drop of brimonidine tartrate 0.15% ophthalmic solution was instilled in the right eye and artificial tear was instilled in the left eye. Pupil size was measured using an infra-red pupillometer under scotopic condition before and at 30 min, 2, 4, 6, 8 and 10 h after instillation. Measurement of margin reflex distance 1 (MRD1) was performed using a millimetre ruler before and after at 10 min after instillation.ResultsThe mean age of the subjects was 32.19 ± 11.43 years (range 10–52 years), 17 were female and 19 were male. Before brimonidine instillation, the mean pupil size was 6.09 ± 1.03 mm in the brimonidine eyes and 6.06 ± 1.04 mm in the control eyes. There was a significant decrease in mean pupil size at 30 min (4.45 ± 1.04), 2 h (4.49 ± 1.06), 4 h (4.59 ± 1.06), 6 h (4.89 ± 1.06) and 8 h (5.38 ± 1.02) after instillation compared to before in brimonidine eyes (p < 0.001 for all). There was a significant miosis continued for at least 6 h (5.95 ± 1.03) in control eyes (p < 0.001). There was no significant change in MRD1, before and after instillation both in brimonidine and control eyes.ConclusionsBrimonidine tartrate 0.15% had a significant miosis under scotopic condition for at least 8 h after instillation and had a significant miosis on the untreated eye for at least 6 h.Subject terms: Outcomes research, Eye manifestations 相似文献
1000.
This study investigated the relationship between psychopathy and tests presumed sensitive to orbitofrontal cortex (OFC) function in a non-criminal student sample. While converging lines of evidence indicate OFC-associated dysfunction in criminal psychopaths, few studies have investigated whether non-criminal psychopaths manifest similar deficits. Psychopathic traits were indexed using the Self-Report Psychopathy scale and the “Sniffin' Sticks” and Iowa Gambling Task (IGT) were employed as neuropsychological measures of OFC function. The results showed higher degrees of psychopathy were significantly associated with poorer olfactory discriminative ability and poorer IGT performance. The discussion focuses on what these findings contribute to the understanding of the psychopathy and OFC relationship, suggesting the degree of OFC-associated dysfunction may be one differentiating factor between criminal and non-criminal psychopaths. 相似文献