Churg-Strauss syndrome in patients with cardiac problems

Clinical observations of patients with Churg-Strauss syndrome and cardiac disorders are reported. In one case, both myocardium and endocardium were affected. Severe cardiac insufficiency was the immediate cause of death in one patient. Another observation revealed a benign variant of the disease associated with exudative pericarditis. A review of domestic and foreign literature concerning cardiac pathology in patients with Churg-Strauss syndrome is presented.     

Abdominal emergencies in systemic vasculitis

Abdominal lesions are characterized in a patient with acute vascular purpura and a patient with polyarteritis. The former patient developed obturation ileus of the small intestine, the latter--necrosis and multiple intestinal and gall bladder perforation with subsequent peritonitis. In both cases the abdominal syndrome was manifestation of the basic disease. Surgical treatment saved life of the patients. Stable remission was achieved after long-term medication.     

Clinical aspects of hypereosinophilia syndrome

To assess clinical peculiarities of hypereosinophilia (HEP), determine approaches to treatment and differential diagnosis of the disease, we examined 115 patients in 1969-2002. We made clinical, laboratory and virusological tests with detection of markers of hepatitis B and C viruses, biopsy of the liver (n = 3), on demand echocardiography, indirect immunofluoresence and enzyme immunoassay of the serum for antibodies to neutrophil cytoplasm in some patients. We grouped patients by the presence of Churg-Strauss syndrome (n = 70), an asthmatic variant of nodular polyarteritis (n = 22), hypereosinophilic syndrome (Loffler 11, n = 15) and eosinophilic pulmonary infiltrates (n = 8). Asthmatic nodular polyarteritis was characterized by high arterial hypertension, frequent finding of HBV, aneurysms and infarctions of the viscera. Bronchial asthma and medicines intolerance were absent, though cardiac failure and other cardiac pathology is frequent. Thus, definition of 4 clinical groups of patients with HEP allows a differential approach to the disease treatment and prognosis.     

异丙酚靶控输注技术在妇科腹腔镜手术中的应用

0引言 异丙酚靶控输注(target controlled infusion, TCI)是以血浆药物浓度为目标的靶控输注技术,具有给药迅速、精确和方便的特点,能使药物浓度和临床效应个体化,血药浓度可随时调整,提高了静脉麻醉的可控性和安全性,目前已在临床逐步推广应用. 妇科腹腔镜手术因操作简便、创伤小、需时短、周转快,要求麻醉能够诱导快、维持期平稳、术毕苏醒迅速. 因此,我们将异丙酚靶控输注用于妇科腹腔镜手术,其体会如下.     

Urologic complications following renal transplantation: role of interventional radiologic procedures

Seventy renal transplant recipients with suspected urologic problems underwent interventional radiologic procedures for further diagnosis and treatment. We found that 28 patients did not have urologic complications. The other 42 patients demonstrated a total of 62 complications, including 40 cases of obstruction, 12 cases of extravasation, and ten collections of pararenal fluid. Ultrasound and nuclear renal scans with both technetium-99m DTPA and iodine-131 hippuran were found to be sensitive screening techniques for the detection of these complications. Fifty of the 51 abnormalities were detected using a combination of these techniques. Percutaneous methods alone were successful in treating 15 urinary obstructions, eight pararenal fluid collections, and five urinary extravasations. We encountered six procedure-related complications, and there were three delayed infectious complications that were related to indwelling nephrostomy tubes. One of these three complications resulted in death. The results of our study suggest that invasive radiologic procedures can be safely used to diagnose and treat urologic complications in renal transplant recipients.     

Crossover use of donated blood for autologous transfusion: report of the Council on Scientific Affairs, American Medical Association

BACKGROUND: Controversy exists concerning whether the costs and potential risks outweigh the potential benefits of "crossover" use in the general blood supply of unutilized blood that was donated for autologous transfusion. STUDY DESIGN AND METHODS: Published articles and reports were identified through systematic search of MEDLINE and review of references cited in previously identified articles, textbooks, and reports. Consultation was made with experts in blood donation and transfusion. Additional peer review was received from the American Medical Association (AMA) Council on Scientific Affairs RESULTS: Concern over infectious disease transmission has led to increased interest in and support for autologous transfusion for individuals having planned surgeries. Different requirements exist for collection, labeling, and screening of blood to be used for autologous versus allogeneic transfusions; therefore, procedures for diverting autologous blood donations to the general blood supply involve considerable expense. Several cost-effectiveness studies of autologous blood donation and transfusion conclude that currently this "crossover" appears to be an expensive procedure yielding little increased benefit from a societal perspective. CONCLUSIONS: The recommendations in this report were adopted as AMA Policy at the AMA Annual Meeting in June 1997. The AMA does not encourage blood collection programs to "cross over" units donated for autologous use to the allogeneic blood supply. Practice guidelines are needed, and should be utilized to ensure parsimony in the use of autologous blood donations and transfusions.