"Covert toxocariasis" in a child treated with low-dose diethylcarbamazine

A girl aged 2.5 years with "covert toxocariasis" was treated with low-dose diethylcarbamazine because of supposed noticeable disseminated Toxocara canis infection without ocular or visceral manifestations. There was marked blood and bone marrow eosinophilia, significant increased Toxocara canis antibody (ELISA) and immunoglobulins E, G and M, leucocytosis and an increased sedimentation rate. She had no geophagia, but often sucked small stones, probably contaminated with faeces from puppies. Symptoms were fever, inactivity, weakness, tiredness and loss of appetite. She was followed clinically and with blood samples throughout a period of three years and four months.     

单鼻孔直入经筛骨垂直板后段经蝶入路切除垂体腺瘤

目的 介绍、推广单鼻孔直入经筛骨垂直板后段经蝶入路切除垂体腺瘤的手术经验，探讨该术式的优越性。方法 2001年10月以来对43例垂体腺瘤采用单鼻孔直入经筛骨垂直板后段经蝶入路手术。结果 本组无手术死亡，平均住院时间1周。随访3～25个月。MR复查示肿瘤全切除32例，近全切除9例，大部分切除2例。有内分泌症状的37例中．10例恢复正常，15例改善，12例同术前。结论 单鼻孔直入经筛骨垂直板后段经蝶手术最大限度地利用了鼻腔的自然间隙，入路直接．手术时间短．创伤轻微．并发症较少．是目前最为理想的经蝶手术术式．     

Correction of protease-protease inhibitor imbalance by intrapulmonary administration of contrical in the treatment of patients with chronic nonspecific lung diseases

The ratio of proteinases and their inhibitors in bronchoalveolar washings was studied in 38 patients with chronic nonspecific diseases of the lungs. A decrease in the inhibitor potential was detected. Contrical, an inhibitor of proteolytic enzymes, was used in the treatment of the patients. A new procedure for trans-thoracic++ intrapulmonary administration of contrical with an ISI-1 needle jet injector was shown to be efficient. It provided delivery of the drug in optimal daily doses immediately into the inflammation focus.