全文获取类型
收费全文 | 149篇 |
免费 | 7篇 |
国内免费 | 27篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 6篇 |
基础医学 | 16篇 |
口腔科学 | 2篇 |
临床医学 | 60篇 |
内科学 | 16篇 |
皮肤病学 | 1篇 |
神经病学 | 4篇 |
特种医学 | 21篇 |
外科学 | 7篇 |
综合类 | 8篇 |
预防医学 | 15篇 |
药学 | 23篇 |
肿瘤学 | 3篇 |
出版年
2021年 | 1篇 |
2020年 | 2篇 |
2018年 | 3篇 |
2017年 | 3篇 |
2016年 | 1篇 |
2015年 | 2篇 |
2014年 | 4篇 |
2013年 | 2篇 |
2012年 | 2篇 |
2011年 | 6篇 |
2010年 | 3篇 |
2009年 | 6篇 |
2008年 | 4篇 |
2007年 | 16篇 |
2006年 | 11篇 |
2005年 | 8篇 |
2004年 | 3篇 |
2003年 | 2篇 |
2002年 | 2篇 |
2001年 | 5篇 |
2000年 | 6篇 |
1999年 | 3篇 |
1998年 | 2篇 |
1997年 | 3篇 |
1996年 | 9篇 |
1995年 | 11篇 |
1994年 | 1篇 |
1993年 | 6篇 |
1992年 | 8篇 |
1991年 | 7篇 |
1990年 | 5篇 |
1989年 | 8篇 |
1988年 | 2篇 |
1987年 | 3篇 |
1986年 | 2篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 3篇 |
1981年 | 1篇 |
1980年 | 4篇 |
1979年 | 2篇 |
1975年 | 2篇 |
1973年 | 1篇 |
1969年 | 2篇 |
排序方式: 共有183条查询结果,搜索用时 15 毫秒
31.
The article contains analysis of Russian and foreign literature on cardiac lesions in patients with system vasculites (SV). The frequency of cardiovascular involvement in various SV forms was evaluated. These forms include non-specific aortoarteritis, giant-cell arteritis, nodular polyarteritis, Kawasaki disease, Wegener's granulomatosis, eosinophilic vasculitiis, and granulomatosis. The authors consider the variants of coronary arterial, endocardial, myocardial, and pericardial involvement, as well as the role of arterial hypertension and the clinical features of different SV with cardiac lesions. Modern diagnostic techniques (echoCG, perfusion myocardial scintigraphy, multispiral computed tomography, and coronaroangiography) are covered. 相似文献
32.
33.
LN Barlow-Mosha DS Bagenda PK Mudiope MC Mubiru LM Butler MG Fowler PM Musoke 《African health sciences》2012,12(3):249-258
Background
Access to pediatric antiretroviral formulations is increasing in resource-limited countries, however adult FDCs are still commonly used by antiretroviral therapy (ART) programs.Objective
To describe long-term effectiveness of using adult FDC of d4T+3TC+NVP (Triomune) in children for HIV treatment.Methods
Clinical, immunologic, and virologic outcomes of HIV-infected ART-naïve children aged six months to 12 years, were evaluated up to 96 weeks post-ART initiation.Results
From March 2004 to June 2006, 104 children were followed with a median age of 5.4 years, median CD4 cell percent and HIV-1 RNA were 11.0% (IQR 6.7–13.9) and 348,846copies/mL (IQR 160,941–681,313) respectively at baseline. Using Kaplan-Meir estimates, 75% of children had undetectable viral loads (<400copies/mL) at 96weeks of ART. Children with a baseline CD4 cell percent >15% were 3 times more likely to achieve viral load <400copies/mL than those with baseline CD4 cell percent <5% after adjusting for baseline age {aHR = 3.03 (1.10–8.32), p=0.03}; no difference was found among those with CD4 cell percent >5–14.9% and <5%.Conclusion
Treatment with generic adult FDC for HIV-infected Ugandan children led to sustained clinical, immunologic and virologic response during 96 weeks of ART. Early initiation of ART is key to achieving virological success. 相似文献34.
目的探讨退行性腰椎侧凸(degenerativelumbarscoliosis,DIS)与骨质疏松症(osteoporosis,OP)两者之间的关系。方法选取2006年6月-2010年6月来我院就诊的DIS患者58例及对照组(非腰椎侧凸的腰痛患者)58例,对DIS组Cobb’s角进行测量,并采用双能x线吸收法检测两组患者腰椎(k~L4)、股骨颈、股骨粗隆和Ward’s三角区骨密度T值,分析患者年龄、Cobb’s角与骨密度T值的相关性。结果DIS组平均骨密度T值为-2.7±1.8,合并OP45例,发病率为77.59%;对照组平均骨密度T值为-1.3±1.0,合并OP8例,发病率为13.79%,两组比较有显著性差异(P〈0.05)。相关分析显示,DIS患者T值与年龄呈正相关(r=-0.318,P〈0.01),与侧凸Cobb’s角无关。结论OP是DLS发病的危险因素,同时年龄越大OP程度越重,但与DLS进展程度无关。临床DLS治疗时要考虑到OP的影响。 相似文献
35.
A. F. Tsyb V. N. Petrov A. G. Konoplyannikov E. V. Saypina L. A. Lepechina S. Sh. Kalsina I. V. Semenkova E. V. Agaeva 《Bulletin of experimental biology and medicine》2008,146(1):158-164
In vitro chemiluminescent test showed that human bone marrow mesenchymal stem cells and conditioned media dose-dependently inhibit
production of reactive oxygen species by macrophages: 50% inhibition of chemiluminescence (compared to biocontrol) was observed
at 1:1 mesenchymal stem cell/macrophage ratio or after addition of 20–25% conditioned media to the incubation medium. The
observed mechanism of inhibition of production of reactive oxygen forms can play an essential role in the formation of local
immunosuppressive microenvironment in the organism after allogenic transplantation of mesenchymal stem cells.
Translated from Kletochnye Tehnologii v Biologii i Medicine, No. 3, pp. 171–178, August, 2008 相似文献
36.
Liane M. Vadheim RD LN CDE Kari A. Brewer RN Darcy R. Kassner BS Karl K. Vanderwood MPH Taryn O. Hall MPH Marcene K. Butcher RD CDE Steven D. Helgerson MD MPH Todd S. Harwell MPH 《The Journal of rural health》2010,26(3):266-272
Purpose: To evaluate the feasibility of translating the Diabetes Prevention Program (DPP) lifestyle intervention into practice in a rural community. Methods: In 2008, the Montana Diabetes Control Program worked collaboratively with Holy Rosary Healthcare to implement an adapted group-based DPP lifestyle intervention. Adults at high risk for diabetes and cardiovascular disease were recruited and enrolled (N = 101). Participants set targets to reduce fat intake and increase physical activity (≥150 mins/week) in order to achieve a 7% weight loss goal. Findings: Eighty-three percent (n = 84) of participants completed the 16-session core program and 65 (64%) participated in 1 or more after-core sessions. Of those completing the core program, the mean participation was 14.4 ± 1.6 and 3.9 ± 1.6 sessions during the core and after core, respectively. Sixty-five percent of participants met the 150-min-per-week physical activity goal during the core program. Sixty-two percent achieved the 7% weight loss goal and 78% achieved at least a 5% weight loss during the core program. The average weight loss per participant was 7.5 kg (range, 0 to 19.7 kg), which was 7.5% of initial body weight. At the last recorded weight in the after core, 52% of participants had met the 7% weight loss goal and 66% had achieved at least a 5% weight loss. Conclusion: Our findings suggest that it is feasible to implement a group-based DPP in a rural community and achieve weight loss and physical goals that are comparable to those achieved in the DPP. 相似文献
37.
38.
V M Provotorov P E Chesnokov Iu L Pritsepov V I Goptarev V N Sushkov E V Zizemskaia G G Semenkova S I Kuznetsova A E Uvarov 《Meditsinskaia tekhnika》1992,(5):28-31
The paper describes the basic circuit of a tussograph, a device that monitors cough in patients with bronchopulmonary diseases. An NKT-I makes it possible to calculate the number of tussive expulsions, total and peak expulsions, as well as to record their time distribution. The device may be useful in the study into the efficacy of new antitussive drugs and the assessment of cough clearance. It can provide an insight into mucociliary clearance. 相似文献
39.
As many as 60 patients with hypereosinophilia of different genesis were examined. 40 of them manifested the clinical (congestive heart failure in 6, tachycardia in 10, cardialgias in 3, murmur in the heart in 13, pericardial murmur in 3) and/or ECG signs (disorders of repolarization in 25, His bundle block in 4, rhythm disorders in 7, pathologic Q waves in 2) of heart injury. In 15 out of the 20 examined, the echocardiography data corresponded to the dilated pattern of heart injury despite the fact that the changes in contractile function of the left ventricle were less appreciable than in 28 patients with dilated cardiomyopathy. In 2 patients who died (one from congestive heart failure and one from anaphylactic shock) the presence of endomyocardial fibrosis with heart dilatation was confirmed on postmortem examination. One female patient with right ventricular failure manifested the characteristic signs of isolated injury to the right ventricle. In 3 patients, the endocardium appeared thickened. None of the cases showed the signs of restrictive heart injury. The data obtained indicate that hypereosinophilia may be one of the etiologic factors of dilated cardiomyopathy. 相似文献
40.
目的确定对诊断准确性进行研究的论著的规范(STARD)公布前、后该类论著的质量改善情况,并比较执行STARD和未执行STARD的杂志的该类论著质量有无差 相似文献