全文获取类型
收费全文 | 1420篇 |
免费 | 78篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 95篇 |
妇产科学 | 12篇 |
基础医学 | 127篇 |
口腔科学 | 53篇 |
临床医学 | 182篇 |
内科学 | 273篇 |
皮肤病学 | 21篇 |
神经病学 | 40篇 |
特种医学 | 316篇 |
外科学 | 173篇 |
综合类 | 12篇 |
预防医学 | 67篇 |
眼科学 | 7篇 |
药学 | 60篇 |
肿瘤学 | 68篇 |
出版年
2023年 | 2篇 |
2022年 | 2篇 |
2021年 | 12篇 |
2020年 | 6篇 |
2019年 | 18篇 |
2018年 | 27篇 |
2017年 | 10篇 |
2016年 | 18篇 |
2015年 | 24篇 |
2014年 | 31篇 |
2013年 | 54篇 |
2012年 | 39篇 |
2011年 | 31篇 |
2010年 | 42篇 |
2009年 | 35篇 |
2008年 | 32篇 |
2007年 | 54篇 |
2006年 | 43篇 |
2005年 | 48篇 |
2004年 | 36篇 |
2003年 | 29篇 |
2002年 | 20篇 |
2001年 | 19篇 |
2000年 | 16篇 |
1999年 | 27篇 |
1998年 | 97篇 |
1997年 | 72篇 |
1996年 | 77篇 |
1995年 | 53篇 |
1994年 | 57篇 |
1993年 | 63篇 |
1992年 | 13篇 |
1991年 | 8篇 |
1990年 | 16篇 |
1989年 | 42篇 |
1988年 | 35篇 |
1987年 | 39篇 |
1986年 | 23篇 |
1985年 | 30篇 |
1984年 | 33篇 |
1983年 | 18篇 |
1982年 | 22篇 |
1981年 | 23篇 |
1980年 | 28篇 |
1979年 | 7篇 |
1978年 | 16篇 |
1977年 | 18篇 |
1976年 | 21篇 |
1975年 | 13篇 |
1930年 | 1篇 |
排序方式: 共有1510条查询结果,搜索用时 0 毫秒
81.
de Knijff DW Schepers PH Blanken-Meijs JT 《Nederlands tijdschrift voor geneeskunde》2001,145(35):1697-1699
A 45-year-old woman of Moroccan origin developed a dilated cardiomyopathy during clozapine treatment for a psychosis that did not respond to conventional antipsychotics. The onset of her illness was acute with chest pain. She subsequently developed shortness of breath and oedema of the face and legs. The cardiomyopathy appeared to be partially reversible after the clozapine was halted. Cardiomyopathy during the use of clozapine is rarely described in the literature, although myocarditis is a known complication. The cause of cardiomyopathy during the use of clozapine is not known. Myocarditis might evolve into cardiomyopathy. There are indications that myocarditis is caused by an allergic reaction to clozapine. It is advised that clozapine treatment should only be initiated under the close supervision of a psychiatrist, and that during the use of clozapine one should be alert to the risk of cardiac complications. 相似文献
82.
HO Garland † K Hamilton S Freeman C Burns M Cusack RJ Balment 《Clinical and experimental pharmacology & physiology》1999,26(10):803-808
1. Infusion experiments were performed on chronically catheterized conscious rats to assess kidney function before and after the induction of diabetes mellitus with streptozotocin. 2. Two infusion regimens were used, a conventional constant-infusion protocol and a novel computer-driven, servo-controlled fluid replacement technique. The latter enables body fluid status to be maintained throughout a study occasion by servo-controlled replacement of spontaneous urinary fluid losses. 3. The chronically catheterized conscious rat infused using a servo-controlled system appears to be the optimum model for a study of diabetic renal function. The conscious preparation circumvents problems associated with anaesthesia and acute surgery. The servo-controlled infusion protocol maintains the altered fluid status of the diabetic condition. Both hyperfiltration and polyuria, characteristics of human diabetes often absent in anaesthetized and/or constantly infused diabetic rats, were seen in all conscious servo-controlled diabetic animals. 4. The new regimen enables a more accurate assessment of renal function in experimental diabetes than with previous protocols. It should prove useful in future studies, particularly those assessing the role of anti-diabetic drugs on the kidney. 相似文献
83.
L Stankler D Lloyd RJ Pollitt ES Gray H Thom G Russell 《Archives of disease in childhood》1982,57(3):212-216
A family is described in which 2 siblings born to healthy parents presented with abnormal facies, persistent diarrhoea, and early death. Exhaustive pathological and biochemical investigations failed to find a cause. The scalp hair of both babies had an abnormal amino-acid composition, and presented an appearance that was unique on scanning electron microscopical examination; this fact and the clinical picture probably represents a new syndrome. 相似文献
84.
85.
Pineal germinoma: MR imaging 总被引:6,自引:0,他引:6
Magnetic resonance (MR) imaging characteristics of pineal germinomas are described in seven patients imaged with MR and computed tomography (CT). In patients with symptoms of an enlarging process in the quadrigeminal plate cistern, MR imaging was as sensitive as CT scanning in detecting the mass. MR imaging did not detect a normal-sized, calcified neoplastic gland. Germinoma, germinoma with embryonal cell carcinoma elements, and pineoblastoma demonstrated different MR signal characteristics. Although direct coronal and sagittal MR images were useful in defining the relationship of the tumor to the posterior third ventricle, Sylvian aqueduct, and vein of Galen, the ease, rapidity, and sensitivity of CT scanning suggest that CT should remain the modality of choice for initial evaluation and screening of the pineal region, especially in the younger pediatric population, in whom detection of calcification may provide the only clue of an abnormality. 相似文献
86.
87.
We characterized neutrophil autoantigens using an immunoblotting technique with antibodies obtained from patients with autoimmune neutropenia. These results were correlated with serologic characterization of the antibodies, using indirect immunofluorescence and leukoagglutination. Of the 17 sera immunoblotted, 16 showed discrete bands in the molecular weight range of 30 to 112. Three patients with Felty's syndrome reacted with an antigenic target of 80 to 84 Kd molecular mass, a finding not seen in any of the other patients studied. By serologic testing, none of the autoimmune sera showed serologic specificity for any known neutrophil-specific alloantigen. Using an anti-NA-1 serum, we identified antigenic targets at 40, 50, and 101 Kd in both NA-1-positive and NA-1-negative neutrophils. Ten of 17 autoimmune sera showed reactivity in this corresponding range. These studies demonstrate that immunoblotting may be used to identify antigenic targets in autoimmune neutropenia and may suggest a specificity of these antibodies not definable by serologic techniques. Correlation of immunoblot reactivity with disease states associated with immune neutropenia may be useful in the study of the pathogenesis of the different forms of autoimmune neutropenia. 相似文献
88.
89.
90.
M Padberg SFTM de Bruijn DLJ Tavy & RJ de Haan 《Cephalalgia : an international journal of headache》2005,25(11):1101-1102