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131.
Soumitra Marathe Bhavuk Dhamija Sushant Kumar Nikita Jain Sarbari Ghosh Jai Prakash Dharikar Sumana Srinivasan Sreya Das Abhijeet Sawant Saloni Desai Farhat Khan Abigail Syiemlieh Manohar Munde Chitra Nayak Mayuri Gandhi Ashutosh Kumar Sanjeeva Srivastava K.V. Venkatesh Rahul Purwar 《The Journal of investigative dermatology》2021,141(8):1932-1942
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Colaco Stacy Achrekar Swati Patil Akshata Sawant Unnati Desai Sadhna Mangoli Vijay Jirge Padma Rekha Modi Deepak Mahale Smita D. 《Journal of assisted reproduction and genetics》2022,39(7):1633-1642
Journal of Assisted Reproduction and Genetics - To evaluate the association of single-nucleotide polymorphisms (SNPs) in the anti-Müllerian hormone (AMH) and AMH type II receptor (AMHR2) genes... 相似文献
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Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy and is a major cause of cancer morbidity and mortality worldwide. Oral cancer is the most predominant malignancy in the Indian subcontinent due to the widespread habits of chewing tobacco and related products. Patients with oral tumours have a high risk of early locoregional relapse. Early detection of disease progression remains a challenging task mainly due to the lack of adequate early prognostic markers. CEA, SCC Ag, CA-125, serum cytokeratin (CK) fragments, Cyfra 21-1 (CK 19), TPS (CK 18), TPA (CK 8, 18, and 19) etc. are being used as serum markers for the prediction of prognosis of various malignancies. This review presents the available literature on serum CK markers in different malignancies evaluates their utility in the management of oral cancer, and identifies the lacunae which need to be addressed to develop sensitive and specific assays for early detection of recurrence, prognosis, and treatment monitoring. 相似文献
136.
Dhir AA Sawant S Dikshit RP Parikh P Srivastava S Badwe R Rajadhyaksha S Dinshaw KA 《Cancer causes & control : CCC》2008,19(2):147-153
Objective To study the cancer pattern among HIV positive cancer cases.
Method The study group included patients registered in the HIV Cancer clinic at the Tata Memorial Hospital (TMH), Mumbai, which is
the largest tertiary referral cancer center in India. We used the gender and age-specific proportions of each cancer site
of the year 2002 that was recorded in the Hospital Cancer Registry to estimate an expected number of various cancer sites
among HIV positive cancer patients during the period 2001–2005. The observed number of site-specific cancer cases was divided
by the expected number to obtain proportional incidence ratio (PIR).
Results No case of Kaposi’s sarcoma was observed. Increased proportion of non- Hodgkin’s lymphoma (NHL) was observed (PIR in males = 17.1,
95%CI 13.33-21.84, females = 10.3, 95%CI 6.10-17.41).In males, PIR was increased for anal cancer (PIR = 10.3, 95%CI 4.30–24.83),
Hodgkin’s disease, testicular cancer, colon cancer, and few head and neck cancer sites. Among females, the PIRs for cervical
cancer (PIR = 4.1, 95%CI 2.90–5.75), vaginal cancer (PIR = 7.7, 95%CI 2.48–23.85), and anal cancer (PIR = 6.5, 95%CI 0.91–45.88)
were increased.
Conclusions The absence of Kaposi’s sarcoma and increased PIRs for certain non –AIDS defining cancers among HIV infected cancer cases
indicates a different spectrum of HIV associated malignancies in this region. The raised PIR for cervical cancer emphasizes
the urgent need for screening programs for cervical cancer among HIV infected individuals in India. 相似文献
137.
Sawant S Amladi ST Wadhawa SL Nayak CS Nikam BP 《Indian journal of dermatology, venereology and leprology》2007,73(4):250-252
A three month-old boy was brought by his mother with complaints of multiple reddish lesions on his trunk and face since birth. The patient had erythematous annular plaques with scaling on his extremities, palms and soles with periorbital erythema and edema giving the characteristic "eye mask" or "owl's eye" appearance. His mother did not have history of any illness. Hemogram, liver and renal function tests were within normal limits. A skin biopsy was suggestive of subacute cutaneous lupus erythematosus. Immunological work-up was positive for antinuclear antibodies (ANA) (1:40) with anti-Ro titers of 3.4 and 3.47 (>1.1 = clinically significant titre) in the mother and child respectively, although negative for anti-La antibodies. The child's electrocardiogram and 2D echocardiography were normal. We are presenting a case of anti-Ro-positive cutaneous lupus erythematosus with an uncommon skin manifestation. 相似文献
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