Ring chromosome 12 resulting from nonrandom telomeric associations with the short arm of chromosome 15 in a cerebellar astrocytoma

Ring chromosome 12 was found in an untreated cerebellar astrocytoma apparently resulting from nonrandom telomeric associations involving the short arm of chromosome 15, and both the long and short arms of chromosome 12. The clonal nonrandom telomeric associations of 15p to both ends of the chromosome 12 were transitory, but appear to be the precursor lesion in the evolution to ring chromosome 12 in this tumor. A multistep process in the formation of a ring chromosome resulting from nonrandom telomeric associations to both telomeres is illustrated. © 1993 Wiley-Liss, Inc.     

A posterior dislocation of the lens in herpes zoster (author's transl)]

The authors report a case of posterior dislocation of the lens during the natural history of a clinical case of herpes zoster. An echographic B-scan study was carried out to reveal the position and the size and the shape of dislocated lens, together with its structure and that of ocular media. After a discussion on the possible aetiology of the lens dislocation it was considered due to herpes zoster disease, and are reported the possible mechanism of zonula alteration.     

Implant therapy in irradiated patients

In this multicenter study, submerged implants were prospectively followed to evaluate their long-term prognosis in irradiated patients. In a total of 77 patients treated for oral or neck cancer, 188 implants were consecutively placed. After a healing period, the successfully integrated implants were restored with 69 removable and 38 fixed restorations. The implants cumulative survival and success rates were evaluated over a period of at least 36 months. In addition, cumulative success rates were calculated for implant subgroups divided per implant site (mandible or maxilla), radiation dosage, and the time interval between the last irradiation and implant placement. During the healing period, 20 implants did not successfully integrate, whereas 168 implants were classified as success (including both survival and success rates). The analysis of implant subgroups showed slightly more favorable cumulative success rate for mandibular implants (98.4%) compared with maxillary implants (57.1%) and clearly better success rate for a radiation dosage minor of 50-Gy doses. A time greater than 12 months as interval between last irradiation and implant placement seems not to promote better clinical results.     

Benign paroxysmal positional vertigo following closed sinus floor elevation procedure: mallet osteotomes vs. screwable osteotomes. A triple blind randomized controlled trial

Objective: To compare mallet osteotomes with screwable osteotomes determining benign paroxysmal positional vertigo (BPPV) following the osteotome closed sinus floor elevation procedure. Materials and Methods: This triple‐blind randomized controlled trial involved 196 patients affected by edentulous atrophic ridges (107 males and 89 females; mean age 62.05±7.10; age range 49–79 years), requiring an osteotome closed sinus floor elevation procedure. Patients were randomly allocated to either a mallet‐osteotomes group (Group 1, n=98) or a screwable osteotomes group (Group 2, n=98). Two different surgeons, blind to the study, performed the closed sinus lift procedure according to the blocks allocation. A complete post‐surgical examination, including the Dix–Hallpike maneuver, was performed on 196 patients before and after surgery. The diagnosis of BPPV was supported by the existence of ageotropic nystagmus concurrent with vertigo. Results: Three patients of Group 1 (3/98–3.06%) showed a BPPV of the posterior semicircular canal omo‐lateral to the implanted side 1 or 2 days after the surgical procedure, which was promptly solved using the Epley re‐positioning maneuver. Conclusions: Preparation of implant beds with osteotome and mallet transmits percussive and vibratory forces capable of detaching the otoliths from their normal location; moreover, the patient's surgical head position favors the displacement of otoliths into the posterior semicircular canal. Implant surgeons should be aware of this possible complication following closed sinus lift procedure and patients should always be informed before undergoing surgery. To cite this article:
Sammartino G, Mariniello M, Scaravilli MS. Benign paroxysmal positional vertigo following closed sinus floor elevation procedure: mallet osteotomes vs. screwable osteotomes. A triple blind randomized controlled trial.
Clin. Oral Impl. Res. 22 , 2011; 669–672
doi: 10.1111/j.1600‐0501.2010.01998.x     

Predominant Brenner Tumor Combined with Struma Ovarii Containing a Papillary Microcarcinoma Associated with Benign Peritoneal Strumosis: Report of a Case and Histologic Features

Brenner tumor and struma ovarii, two uncommon ovarian tumors arising alone or together with dermoid cysts or adenomas, are both rare entities. Both tumors rarely become malignant and rarely metastasize. Few published reports describe coexisting Brenner tumor and malignant struma ovarii. Patients in whom these malignancies coexist only occasionally have peritoneal spreading, strumosis, or a history of thyrotoxicosis. The patient we describe, a 74-year-old woman, presented with a 2 months’ history of lower abdominal pain and episodic intestinal subocclusion due to a complex pelvic mass. The mass consisted predominantly of a Brenner tumor associated with struma ovarii containing a single small island of thyroid tissue that had undergone malignant transformation into a well-differentiated papillary carcinoma and also normal thyroid tissue that had spread to the peritoneum. The patient underwent radical surgical treatment and after 7 years follow-up is disease free.     

Consensus conference on immediate loading: the single tooth and partial edentulous areas

PURPOSE: A consensus conference was held to determine what the parameters should be for the immediate functional loading of the single-tooth implant restoration and short-span fixed implant-supported bridgework. MATERIALS: Forty-one clinicians and researchers presented cases and situations relating to the topic. A panel then distilled questions that were presented to the audience (430) at large. Answers were gleaned to formulate a consensus. RESULTS: Ten distinct answers evolved that constituted the essence of guidelines for clinicians to be aware of when undertaking immediate loading. These guidelines are contained within the body of the text. CONCLUSIONS: Extreme caution and adherence to a universal generic protocol are suggested for clinicians who are involved with single-tooth and short-span multiple-teeth implant replacements as related to immediate loading as defined within this text.