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Alessandra Mazzo José Carlos Amado Martins Beatriz Maria Jorge Rui Carlos Negr?o Batista Rodrigo Guimar?es dos Santos Almeida Fernando Manuel Dias Henriques Verónica Rita Dias Coutinho Isabel Amélia Costa Mendes 《Revista latino-americana de enfermagem》2015,23(5):814-820
Objective:
to validate an instrument to measure self-confidence of nursing care in urinary retention.Methods:
methodological research study, carried out after ethical approval. A Likert-like scale of 32 items related to nursing care in urinary retention was applied to students of the graduate nursing course. For instrument validation, analysis of the sample adequacy and main components, Varimax orthogonal rotation and internal consistency analyses were developed.Results:
in a sample of 305 students, there was high correlation of all items with the total scale and Cronbach''s alpha of 0.949. The scale items were divided into five factors with internal consistency: Factor 1 (0.890), Factor 2 (0.874), Factor 3 (0.868), Factor 4 (0.814) and Factor 5 (0.773), respectively.Conclusion:
the scale meets the validity requirements, demonstrating potential for use in evaluation and research. 相似文献93.
Rodrigo Guimar?es dos Santos Almeida Alessandra Mazzo José Carlos Amado Martins Rui Carlos Negr?o Baptista Fernanda Berchelli Gir?o Isabel Amélia Costa Mendes 《Revista latino-americana de enfermagem》2015,23(6):1007-1013
Objective:
translate and validate to Portuguese the Scale of Student Satisfaction and Self-Confidence in Learning.Material and Methods:
methodological translation and validation study of a research tool. After following all steps of the translation process, for the validation process, the event III Workshop Brazil - Portugal: Care Delivery to Critical Patients was created, promoted by one Brazilian and another Portuguese teaching institution.Results:
103 nurses participated. As to the validity and reliability of the scale, the correlation pattern between the variables, the sampling adequacy test (Kaiser-Meyer-Olkin) and the sphericity test (Bartlett) showed good results. In the exploratory factorial analysis (Varimax), item 9 behaved better in factor 1 (Satisfaction) than in factor 2 (Self-confidence in learning). The internal consistency (Cronbach''s alpha) showed coefficients of 0.86 in factor 1 with six items and 0.77 for factor 2 with 07 items.Conclusion:
in Portuguese this tool was called: Escala de Satisfação de Estudantes e Autoconfiança na Aprendizagem. The results found good psychometric properties and a good potential use. The sampling size and specificity are limitations of this study, but future studies will contribute to consolidate the validity of the scale and strengthen its potential use. 相似文献94.
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Matthieu Jabaudon Raiko Blondonnet Bruno Pereira Rodrigo Cartin-Ceba Christoph Lichtenstern Tommaso Mauri Rogier M. Determann Tomas Drabek Rolf D. Hubmayr Ognjen Gajic Florian Uhle Andrea Coppadoro Antonio Pesenti Marcus J. Schultz Marco V. Ranieri Helena Brodska Ségolène Mrozek Vincent Sapin Michael A. Matthay Jean-Michel Constantin Carolyn S. Calfee 《Intensive care medicine》2018,44(9):1388-1399
Purpose
The soluble receptor for advanced glycation end-products (sRAGE) is a marker of lung epithelial injury and alveolar fluid clearance (AFC), with promising values for assessing prognosis and lung injury severity in acute respiratory distress syndrome (ARDS). Because AFC is impaired in most patients with ARDS and is associated with higher mortality, we hypothesized that baseline plasma sRAGE would predict mortality, independently of two key mediators of ventilator-induced lung injury.Methods
We conducted a meta-analysis of individual data from 746 patients enrolled in eight prospective randomized and observational studies in which plasma sRAGE was measured in ARDS articles published through March 2016. The primary outcome was 90-day mortality. Using multivariate and mediation analyses, we tested the association between baseline plasma sRAGE and mortality, independently of driving pressure and tidal volume.Results
Higher baseline plasma sRAGE [odds ratio (OR) for each one-log increment, 1.18; 95% confidence interval (CI) 1.01–1.38; P?=?0.04], driving pressure (OR for each one-point increment, 1.04; 95% CI 1.02–1.07; P?=?0.002), and tidal volume (OR for each one-log increment, 1.98; 95% CI 1.07–3.64; P?=?0.03) were independently associated with higher 90-day mortality in multivariate analysis. Baseline plasma sRAGE mediated a small fraction of the effect of higher ΔP on mortality but not that of higher VT.Conclusions
Higher baseline plasma sRAGE was associated with higher 90-day mortality in patients with ARDS, independently of driving pressure and tidal volume, thus reinforcing the likely contribution of alveolar epithelial injury as an important prognostic factor in ARDS. Registration: PROSPERO (ID: CRD42018100241).97.
Rubens A. da Silva Edgar R. Vieira Karen B. P. Fernandes Rodrigo A. Andraus Marcio R. Oliveira Leandro A. Sturion 《Disability and rehabilitation》2018,40(11):1294-1300
Purpose: To compare the balance of individuals with and without chronic low back pain during five tasks.Method: The participants were 20 volunteers, 10 with and 10 without nonspecific chronic low back pain, mean age 34?years, 50% females. The participants completed the following balance tasks on a force platform in random order: (1) two-legged stance with eyes open, (2) two-legged stance with eyes closed, (3) semi-tandem with eyes open, (4) semi-tandem with eyes closed and (5) one-legged stance with eyes open. The participants completed three 60-s trials of tasks 1–4, and three 30-s trials of task 5 with 30-s rests between trials. The center of pressure area, velocity and frequency in the antero-posterior and medio-lateral directions were computed during each task, and compared between groups and tasks.Results: Participants with chronic low back pain presented significantly larger center of pressure area and higher velocity than the healthy controls (p?0.001). There were significant differences among tasks for all center of pressure variables (p?0.001). Semi-tandem (tasks 3 and 4) and one-leg stance (task 5) were more sensitive to identify balance impairments in the chronic low back pain group than two-legged stance tasks 1 and 2 (effect size >1.37 vs. effect size <0.64). There were no significant interactions between groups and tasks.Conclusions: Individuals with chronic low back pain presented poorer postural control using center of pressure measurements than the healthy controls, mainly during more challenging balance tasks such as semi-tandem and one-legged stance conditions.
- Implications for Rehabilitation
People with chronic low back had poorer balance than those without it.
Balance tasks need to be sensitive to capture impairments.
Balance assessments during semi-tandem and one-legged stance were the most sensitive tasks to determine postural control deficit in people with chronic low back.
Balance assessment should be included during rehabilitation programs for individuals with chronic low back pain for better clinical decision making related to balance re-training as necessary.
98.
99.
Sialic acids are monosaccharides typically found on cell surfaces and attached to soluble proteins, or as essential components of ganglioside structures that play a critical role in brain development and neural transmission. Human milk also contains sialic acid conjugated to oligosaccharides, glycolipids, and glycoproteins. These nutrients can reach the large bowel where they may be metabolised by the microbiota. However, little is known about the members of the microbiota involved in this function. To identify intestinal bacteria that utilise sialic acid within a complex intestinal community, we cultured the caecal microbiota from piglets in the presence of 13C-labelled sialic acid. Using RNA-based stable isotope probing, we identified bacteria that consumed 13C-sialic acid by fractionating total RNA in isopycnic buoyant density gradients followed by 16S rRNA gene analysis. Addition of sialic acid caused significant microbial community changes. A relative rise in Prevotella and Lactobacillus species was accompanied by a corresponding reduction in the genera Escherichia/Shigella, Ruminococcus and Eubacterium. Inspection of isotopically labelled RNA sequences suggests that the labelled sialic acid was consumed by a wide range of bacteria. However, species affiliated with the genus Prevotella were clearly identified as the most prolific users, as solely their RNA showed significantly higher relative shares among the most labelled RNA species. Given the relevance of sialic acid in nutrition, this study contributes to a better understanding of their microbial transformation in the intestinal tract with potential implications for human health. 相似文献
100.
Rodolfo Gonzalez Camargo Daniela Mendes dos Reis Riccardi Henrique Quintas Teixeira Ribeiro Luiz Carlos Carnevali Jr. Emidio Marques de Matos-Neto Lucas Enjiu Rodrigo Xavier Neves Joanna Darck Carola Correia Lima Raquel Galv?o Figuerêdo Paulo Sérgio Martins de Alcantara Linda Maximiano José Otoch Miguel Luiz Batista Jr. Gerhard Püschel Marilia Seelaender 《Nutrients》2015,7(6):4465-4479