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排序方式: 共有1075条查询结果,搜索用时 46 毫秒
101.
Blom Maartje Pico-Knijnenburg Ingrid van Montfrans Joris M. Bredius Robbert G. M. van der Burg Mirjam Swen Jesse J. Berghuis Dagmar 《Journal of clinical immunology》2022,42(1):199-202
Journal of Clinical Immunology - 相似文献
102.
Older coronary thrombus is an independent predictor of 1‐year mortality in acute myocardial infarction 下载免费PDF全文
103.
Mohammad Abdelghani Ben Ren Ernest Spitzer Hiroki Tateishi Hans Jonker Marcel L. Geleijnse Jan G. Tijssen Robbert J. de Winter Patrick W. J. C. Serruys Osama I. I. Soliman 《The international journal of cardiovascular imaging》2016,32(10):1519-1527
Paravalvular leak (PVL) after transcatheter aortic valve implantation (TAVI) is challenging to quantitate. Transthoracic echocardiography (TTE) is the main tool used for the assessment of PVL but is modestly reproducible. We sought to develop a reproducible echocardiographic approach to assess PVL in the post-TAVI setting. Four observers independently analyzed eleven parameters of PVL severity in 50 pre-discharge TTE studies performed after TAVI. The parameters included color-Doppler parameters [jet circumferential extent (CE) and planimetered vena contracta area in the short-axis view and jet breadth and qualitative features in the long-axis views], continuous-wave Doppler parameters [jet velocity time integral (VTI) and pressure half time (PHT)], quantitative Doppler parameters (regurgitation volume and fraction and effective regurgitant orifice area), aortic diastolic flow reversal and valve stent eccentricity. Intraclass correlation coefficient (ICC) and coefficient of variation (CV) for numerical parameters and kappa coefficient (κ) for categorical parameters were calculated for inter- and intra-observer comparisons. Inter-observer ICC was highest and CV lowest for CE (0.88 and 0.36), jet origin breadth (0.82 and 0.39), jet qualitative features in long-axis views (0.87 and 0.26), jet VTI (0.87 and 0.04) and PHT (0.73 and 0.10). Similar results were found in intra-observer comparisons. A 2-step granular approach combining the most reproducible parameters was used to grade PVL by the four observers. Inter-observer agreement was achieved in 86?% of cases (κ?=?0.79). Combining color Doppler and continuous wave Doppler parameters in a granular algorithm yields excellent reproducibility of PVL assessment by TTE. 相似文献
104.
Yohei Sotomi Hiroki Tateishi Pannipa Suwannasom Jouke Dijkstra Jeroen Eggermont Shengnan Liu Erhan Tenekecioglu Yaping Zheng Mohammad Abdelghani Rafael Cavalcante Robbert J. de Winter Joanna J. Wykrzykowska Yoshinobu Onuma Patrick W. Serruys Takeshi Kimura 《The international journal of cardiovascular imaging》2016,32(6):871-883
The degree of stent/scaffold embedment could be a surrogate parameter of the vessel wall-stent/scaffold interaction and could have biological implications in the vascular response. We have developed a new specific software for the quantitative evaluation of embedment of struts by optical coherence tomography (OCT). In the present study, we described the algorithm of the embedment analysis and its reproducibility. The degree of embedment was evaluated as the ratio of the embedded part versus the whole strut height and subdivided into quartiles. The agreement and the inter- and intra-observer reproducibility were evaluated using the kappa and the interclass correlation coefficient (ICC). A total of 4 pullbacks of OCT images in 4 randomly selected coronary lesions with 3.0 × 18 mm devices [2 lesions with Absorb BVS and 2 lesions with XIENCE (both from Abbott Vascular, Santa Clara, CA, USA)] from Absorb Japan trial were evaluated by two investigators with QCU-CMS software version 4.69 (Leiden University Medical Center, Leiden, The Netherlands). Finally, 1481 polymeric struts in 174 cross-sections and 1415 metallic struts in 161 cross-sections were analyzed. Inter- and intra-observer reproducibility of quantitative measurements of embedment ratio and categorical assessment of embedment in Absorb BVS and XIENCE had excellent agreement with ICC ranging from 0.958 to 0.999 and kappa ranging from 0.850 to 0.980. The newly developed embedment software showed excellent reproducibility. Computer-assisted embedment analysis could be a feasible tool to assess the strut penetration into the vessel wall that could be a surrogate of acute injury caused by implantation of devices. 相似文献
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108.
Indira Tendolkar Guido van Wingen Maren Urner Robbert Jan Verkes Guill��n Fern��ndez 《Neuropsychopharmacology》2011,36(11):2266-2275
It is unknown how antidepressants reverse mood-congruent memory bias, a cognitive core factor causing and maintaining depression. Using a double-blind, placebo-controlled, cross-over design, we investigated the effect of a short-term treatment (14 days) with the dual reuptake inhibitor duloxetine on neural correlates of mood-congruent and mood-incongruent memory formation and retrieval in healthy volunteers who underwent a sad mood induction procedure. Duloxetine did not affect acute mood state or memory performance, but interacted with brain processes mediating mood-congruent memory. It decreased activity related to successful memory formation for mood-congruent and -incongruent items in a set of brain regions comprising the putamen and the middle frontal gyrus, as well as the middle and the anterior cingulate cortex. Duloxetine specifically increased amygdala activity related to successful memory retrieval for mood-incongruent items. Here we show that short-term administration of duloxetine affects the neural correlates of emotional memory formation and retrieval in a set of brain regions whose processing is related to affective state and its regulation. While duloxetine suppressed the neural correlates of emotional memory formation in general, it specifically enhanced amygdala processes associated with mood-incongruent memory retrieval. This pattern of results shows how an antidepressant may reduce emotional memory formation and reverse mood-congruent processing biases at retrieval. 相似文献
109.
Ghassemi AH van Steenbergen MJ Barendregt A Talsma H Kok RJ van Nostrum CF Crommelin DJ Hennink WE 《Pharmaceutical research》2012,29(1):110-120
Purpose
To investigate the in vitro release of octreotide acetate, a somatostatin agonist, from microspheres based on a hydrophilic polyester, poly(D,L-lactide-co-hydroxymethyl glycolide) (PLHMGA). 相似文献110.
Hagedoorn M Dagan M Puterman E Hoff C Meijerink WJ Delongis A Sanderman R 《Journal of behavioral medicine》2011,34(4):288-297
Based on attribution theory, this study hypthesized that past spousal supportiveness may act as a moderator of the link between
one partner’s current support behavior and the other partner’s relationship satisfaction. A sample of 88 patients with colorectal
cancer and their partners completed questionnaires approximately 3 and 9 months after diagnosis. The data were analyzed employing
dyadic data analytic approaches. In the short-term, spousal active engagement—which involved discussing feelings and engaging
in joint problem solving—was positively associated with relationship satisfaction in patients as well as in partners, but
only when past spousal support was relatively low. Spousal protective buffering—which involved hiding worries and fears and
avoiding talking about the disease—was negatively associated with relationship satisfaction in patients, again only when past
spousal support was relatively low. If past spousal support was high, participants rated the quality of their relationship
relatively high, regardless of their partner’s current support behavior. Over time, past spousal supportiveness was not found
to mitigate the negative association between spousal protective buffering and relationship satisfaction. Overall, our results
indicate that relationship satisfaction can be maintained if past spousal supportiveness is high even if the partner is currently
not very responsive to the individual’s needs, at least in the short-term. 相似文献