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排序方式: 共有3039条查询结果,搜索用时 15 毫秒
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Roxana Pollack Bertina Kreshpaj Johanna Jonsson Theo Bodin Virginia Gunn Cecilia Orellana Per-Olof
stergren Carles Muntaner Nuria Matilla-Santander 《Scandinavian journal of work, environment & health》2022,48(5):351
ObjectiveThis study aimed to examine the effects of low-quality employment trajectories on severe common mental disorders (CMD) according to Swedish and foreign background.MethodsIn this longitudinal study based on Swedish population registries (N=2 703 687), low- and high-quality employment trajectories were the main exposures observed across five years (2005–2009), with severe CMD as outcome variable (2010–2017). Adjusted hazard ratios (HR) were calculated by means of Cox regression models and stratified according to Swedish and foreign background [first-generation (i) EU migrants, (ii) non-EU migrants, (iii) second-generation migrants, (iv) Swedish-born of Swedish background] and sex. The reference group was Swedish-born of Swedish background in a constant high-quality employment trajectory.ResultsSecond-generation migrants had an increased risk of CMD compared to Swedish-born of Swedish background when following low-quality employment trajectories [eg, male in constant low-quality HR 1.54, 95% confidence interval (CI) 1.41–1.68]. Female migrant workers, especially first-generation from non-EU countries in low-quality employment trajectories (eg, constant low-quality HR 1.66, 95% CI 1.46–1.88), had a higher risk of CMD compared to female Swedish-born of Swedish background. The risk for CMD according to employment trajectories showed little differences between first- and second-generation migrants.ConclusionLow-quality employment trajectories appear to be determinants of risk for CMD in association with Swedish or foreign background of origin and sex. Our study shows a higher risk for severe CMD in second-generation and non-EU migrant compared to Swedish-born of Swedish background in constant low-quality employment. Further qualitative research is recommended to understand the mechanism behind the differential mental health impact of low-quality employment trajectories according to foreign background. 相似文献
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Scott R. Pollack David J. Schenk 《Journal of labelled compounds & radiopharmaceuticals》2015,58(11-12):433-441
Omeprazole (Prilosec®) is a selective and irreversible proton pump inhibitor used to treat various medical conditions related to the production of excess stomach acids. It functions by suppressing secretion of those acids. Radiolabeled compounds are commonly employed in the drug discovery and development process to support efforts including library screening, target identification, receptor binding, assay development and validation and safety assessment. Herein, we describe synthetic approaches to the controlled and selective labeling of omeprazole with tritium via hydrogen isotope exchange chemistry. The chemistry may also be used to prepare tritium labeled esomeprazole (Nexium®), the active pure (S)‐enantiomer of omeprazole. 相似文献
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Geoffrey Pollack MD Aron Pollack MS Joel Delfiner MD John Fernandez MD 《The Laryngoscope》2009,119(10):1941-1946
Methylene blue has been used to help facilitate parathyroid surgery for over 30 years. Its use has been widely considered both safe and cost effective. Twenty‐six cases of a toxic metabolic encephalopathy, however, have been reported with its use. As a result, some surgeons have stopped using this technique altogether. It is now known that methylene blue is a monoamine oxidase inhibitor. When combined with drugs that increase central serotonin neurotransmission, serotonin toxicity results. This is the cause of the encephalopathy described in the literature. A case report, review of the literature, and guidelines as to its proper use are presented so as to allow for safe parathyroid surgery. Laryngoscope, 2009 相似文献
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Shock following generalized hypoxic-ischemic injury in previously healthy infants and children 总被引:1,自引:0,他引:1
Eighteen previously healthy patients with hypoxic-ischemic shock were observed longitudinally by means of data measured or derived from systemic arterial and pulmonary artery catheters. Shock was characterized by low cardiac index, elevated right and left heart filling pressures, elevated systemic and pulmonary vascular resistances, decreased oxygen consumption, and elevated oxygen extraction indices. Oxygen consumption was significantly correlated with oxygen delivery (r = 0.74, P less than 0.0001). This pattern fits that of cardiogenic shock. Cardiopulmonary data were not significantly different in survivors (n = 10) and nonsurvivors (n = 8). Outcome was determined by neurologic injury. 相似文献
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J. Rechenberger und Ch. Pollack 《Clinical and experimental medicine》1945,114(1-2):200-208
Zusammenfassung Im Versuch am Menschen wird mit einer extrem niedrigen Eisenzufuhr von 0,27 bzw. 0,37 mg Eisen pro Tag in der Kotausscheidung
Gleichgewicht erreicht. Der Eisengehalt des Harnes erweist sich mit 0–24 γ pro Tag als so minimal, da? er vernachl?ssigt werden
kann. Aus diesen Versuchen wird geschlossen, da? ein exogener Eisenstoffwechsel des gesunden Erwachsenen in der Regel nicht
besteht, d. h. es findet weder eine Resorption, noch die so oft diskutierte Ausscheidung durch den Dickdarm statt. Das im
Kot erscheinende Eisen entspricht dem Nahrungseisen.
Einige orientierende Serumeisenuntersuchungen lie?en im Rahmen des Versuches keinen Einflu? der eisenarmen Ern?hrung auf den
Serumeisenspiegel erkennen. 相似文献
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