Relationship between liver fibrosis criteria and syndrome-type of TCM in patients with non-alcoholic fatty liver

To explore the relationship between the liver fibrosis criteria and TCM Syndrome type in patients suffering from non-alcoholic fatty liver. Methods: Seventy-nine patients with non-alcoholic fatty liver diagnosed by B ultrasonography were classified by TCM Syndrome Differentiation and their liver fibrosis criteria was determined and compared with those of the healthy subjects as control. Results: Levels of procollagen Ⅲ (PCⅢ), hyaluronic acid (HA), collagen Ⅳ(CⅣ) and laminin (LN) in the fatty liver group were significantly higher than those in the control group (P＜0.05, P＜0.01). In respect to the TCM Syndrome-types, PCⅢ, CⅣ and LN in patients of Phlegm-stasis combined type were significantly higher than those in patients of Spleen deficiency-Phlegm dampness Syndrome-type and Damp-Heat Syndrome-type (P＜0.05, P＜0.01), while HA in different groups was insignificantly different (P＞0.05). Conclusion: There was trend of liver fibrosis in fatty liver patients. It was indicated that the Phlegm-stasis combined Syndrome-type possibly was the main TCM pathologic factor of the increasing of fibrosis criteria for non-alcoholic fatty liver.     

Present status of study on reversion of anti-leukemic multidrug resistance

Ｏｎｅｏｆｔｈｅｒｅａｓｏｎｓｆｏｒｆａｉｌｕｒｅｏｆｃｈｅｍｏｔｈｅｒａｐｙｉｎｔｒｅａｔｉｎｇｌｅｕｋｅｍｉａｉｓｔｈａｔｔｈｅｌｅｕｋｅｍｉｃｃｅｌｌｓｐｒｅｓｅｎｔｄｒｕｇｔｏｌｅｒａｎｃｅｔｏｃｈｅｍｏｔｈｅｒａｐｅｕｔｉｃａｇｅｎｔｓ．Ｔｈｅｃｕｒ ｒｅｎｔｈｏｔｐｏｉｎｔｏｆａｎｔｉ ｌｅｕｋｅｍｉｃｄｒｕｇｔｏｌｅｒａｎｃｅｒｅｓｅａｒｃｈｉｓｍｕｌｔｉｄｒｕｇｒｅｓｉｓｔａｎｃｅ（ＭＤＲ）．ＭＤＲｃｏｕｌｄｂｅｇｅｎ ｅｒａｌｌｙｄｉｖｉｄｅｄａｃｃｏｒｄｉｎｇｔｏｉｔｓｍｅｃｈ…     

Clinical observation on effect of shuanghuang shengbai granule on chemotherapy induced myelpsuppression in tumor patients and on ultrastructure of bone marrow in mice

To observe the leucocyte increasing effect of Shuanghuang Shengbai Granule (SHSBG) in tumor patients treated by chemotherapy and the bone marrow microenvironment protecting effect in mice.

Methods  

Patients of non-small-cell pulmonary, mammary, gastric or intestinal cancer, who were ready for receiving re-treatment of chemotherapy, were enrolled and divided into 4 groups randomly. The 28 cases in SHSBG group A received chemotherapy combined with SHSBG; the 27 in the SHSBG group B received chemotherapy alone at first, and SHSBG was added when their peripheral white blood cell (WBC) count lowered to <4×10⁹/L; the 33 in control group A and 24 in control group B were treated by the method similar to that applied to SHSBG group A and B respectively but with Rubidate instead of SHSBG. Experimental study of electron microscopic observation on bone marrow ultrastructure in mice was also conducted.     

原发性高血压患者心率变异及其昼夜节律变化

目的探讨原发性高血压患者心率变异及其昼夜节律变化规律。方法对126例原发性高血压患者进行24h及每小时心率变异时域分析,并与年龄匹配的对照组比较,同时比较高血压伴与不伴左心室肥厚者心率变异及其昼夜节律变化。结果原发性高血压患者时域分析各项指标均下降(P＜0.01),高血压伴左心室肥厚组rMSSD、pNN50进一步降低(P＜0.01),昼夜节律消失。结论原发性高血压患者心率变异减低,自主神经功能受损,平衡失调。高血压伴左心室肥厚者迷走神经功能进一步受损,昼夜节律消失。     

用SF—36量表评价慢性病患者的生命质量

目的 用SF－36量表分析慢性疾病对生命质量的影响。方法 在四川省某城乡用SP－36量表对438名慢性疾病患者进行调查,并按照ICD－8进行疾病分类,对不同系统疾病患者的生命质量进行分析。结果 不同系统疾病患者的生命质量在SF－36量表所测的不同领域均低于一般人群（≥40岁）,不同系统疾病患者在躯体活动性能、社会功能、活力和心理功能四个领域均有差别。影响生命质量的主要疾病有精神疾患、血液及造血器官疾病,传染病和寄生虫病。结论 慢性病降低了患者的生命质量。不同系统疾病对生命质量的影响程度不同,SF－36量表适用于评价慢性病患者的生命质量。在慢性疾病的预防控制中,生命质量应作为健康评价指标。     

^153Sm—EDTMP骨摄取率测定及其与疗效的关系

目的 采用全身显像法测定^153Sm-EDTMP（乙二胺四甲撑膦酸）骨摄取率,并探讨骨摄取率与疗效之间的关系。方法 使用Elscint双探头γ相机,于注射^153Sm-EDTMP后10分钟和6小时,对66例骨转移癌患者进行全身显像并测定骨摄取率。结果 66例患者全身显像法测定的骨摄取率范围在31．9％－86．6％之间,平均56．0％,^153Sm-EDTMP骨摄取率高的患者的总体疗效好干骨摄取率低的患者。根据显像法测定的骨摄取率,以红骨髓吸收剂量限制在1400mGy为标准进行个体化给药,66例患者所接受的治疗剂量在1．40－2．27GBq之间（平均1.90GBq）,骨髓吸收剂量在1370－1430mGy之间（平均1400mGy）。结论 通过测定^153Sm-EDTMP进行安全而有效的个体化给药,在达到治疗效果的同时,避免了骨髓毒性反应的发生,具有重要的临床应用价值。     

病案首页的准确填写与统计报表的关系

病案首页是医院医疗统计最基本的数据,《中华人民共和国统计法》第二条规定:“统计的基本任务是对国民经济和社会发展情况进行统计调查、统计分析,提供统计资料和统计咨询意见,实行统计监督。”数据不准确为上级卫生行政部门了解和掌握居民的医疗需求,医疗服务情况,编制区域医疗规划与卫生事业发展计划,评价医疗服务的社会效益和经济效益,对领导部门决策、与世界各国的资料交流等都会产生不良影响。所以病案首页的准确填写很重要,要认真、如实、规范才能真正反映实际情况。现就常见不规范或填写不准确的主要情况列出如下:     

急性冠状动脉综合征血沉和C-反应蛋白检测及临床意义

目的　观察急性冠状动脉综合征患者血沉 (ESR)和C -反应蛋白 (CRP)阳性率 ,推断炎症反应在急性冠脉事件中的作用 ,及抗炎治疗对其影响。方法　测定 5 8例急性冠脉综合征患者的ESR和CRP阳性率 ,并与对照组进行比较。再分为抗炎组 ,非抗炎组 ,于治疗 1周后复查ESR和CRP ,进行治疗前后比较。结果　急性冠脉综合征患者ESR和CRP阳性率明显增高 ,抗炎后下降较明显。结论　作为炎症标记物 ,ESR值、CRP阳性率可作为预测因子 ,抗炎治疗在急性冠脉事件中可能是有益的     

Effect of l-carnitine supplementation on renal anemia in patients on hemodialysis: a meta-analysis

International Urology and Nephrology - l-carnitine is an amino acid derivative that is thought to be helpful for treating renal anemia in hemodialysis patients. However, the mechanism remains to be...     

Efficacy of non-ablative fractional 1440-nm laser therapy for treatment of facial acne scars in patients with rosacea: a prospective,interventional study

Lasers in Medical Science - Acne scarring is one of the most common facial skin disorders. The appropriate treatments for acne scars in patients with rosacea have not been studied. This study was...